(–)-Epigallocatechin-3- O -gallate (EGCG), the most abundant component of catechins in tea ( Camellia sinensis (L.) O. Kuntze), plays a role against viruses through inhibiting virus invasiveness, restraining gene expression and replication. In this paper, the antiviral effects of EGCG on various viruses, including DNA virus, RNA virus, coronavirus, enterovirus and arbovirus, were reviewed. Meanwhile, the antiviral effects of the EGCG epi -isomer counterpart (+)-gallocatechin-3- O -gallate (GCG) were also discussed.
All Keywords
【저자키워드】 COVID-19, Antiviral, SARS-CoV, EGCG, tea polyphenol, 【초록키워드】 viruses, coronavirus, Gene Expression, antiviral effects, virus, Antiviral effect, Replication, RNA virus, EGCG, enterovirus, arbovirus, DNA virus, Camellia sinensis, gallate, epigallocatechin, inhibiting, GCG, 【제목키워드】 application, green, Effect, tea, Potential,
【저자키워드】 COVID-19, Antiviral, SARS-CoV, EGCG, tea polyphenol, 【초록키워드】 viruses, coronavirus, Gene Expression, antiviral effects, virus, Antiviral effect, Replication, RNA virus, EGCG, enterovirus, arbovirus, DNA virus, Camellia sinensis, gallate, epigallocatechin, inhibiting, GCG, 【제목키워드】 application, green, Effect, tea, Potential,
(–)-Epigallocatechin-3-O -gallate(EGCG)는 차(Camellia sinensis (L.) O. Kuntze)의 가장 풍부한 카테킨 성분으로, 바이러스 침입을 억제하고 유전자 발현 및 복제를 억제하여 바이러스에 대항하는 역할을 합니다. . 본 논문에서는 DNA 바이러스, RNA 바이러스, 코로나바이러스, 엔테로바이러스, 아르보바이러스 등 다양한 바이러스에 대한 EGCG의 항바이러스 효과를 검토하였다. 한편, EGCG 에피-이성체 대응물(+)-갈로카테킨-3-O-갈레이트(GCG)의 항바이러스 효과에 대해서도 논의했다.