Intense transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Africa might promote emergence of variants. We describe 10 SARS-CoV-2 lineages in Benin during early 2021 that harbored mutations associated with variants of concern. Benin-derived SARS-CoV-2 strains were more efficiently neutralized by antibodies derived from vaccinees than patients, warranting accelerated vaccination in Africa.
All Keywords
【저자키워드】 COVID-19, coronavirus disease, severe acute respiratory syndrome coronavirus 2, viruses, respiratory infections, zoonoses, SARS-CoV-2, mutations, variant of concern, West Africa, Benin, 【초록키워드】 coronavirus, vaccination, Mutation, antibody, variants of concern, Transmission, severe acute respiratory syndrome Coronavirus, variants, respiratory, patients, acute respiratory syndrome, acute respiratory syndrome coronavirus, acute respiratory syndrome coronavirus 2, vaccinees, SARS-CoV-2 strain, SARS-CoV-2 lineage, neutralized, vaccinee, promote, accelerated, 【제목키워드】 concern,
【저자키워드】 COVID-19, coronavirus disease, severe acute respiratory syndrome coronavirus 2, viruses, respiratory infections, zoonoses, SARS-CoV-2, mutations, variant of concern, West Africa, Benin, 【초록키워드】 coronavirus, vaccination, Mutation, antibody, variants of concern, Transmission, severe acute respiratory syndrome Coronavirus, variants, respiratory, patients, acute respiratory syndrome, acute respiratory syndrome coronavirus, acute respiratory syndrome coronavirus 2, vaccinees, SARS-CoV-2 strain, SARS-CoV-2 lineage, neutralized, vaccinee, promote, accelerated, 【제목키워드】 concern,
아프리카에서 중증 급성 호흡기 증후군 코로나바이러스 2(SARS-CoV-2)의 강렬한 전파는 변이체의 출현을 촉진할 수 있습니다. 우리는 2021년 초 베냉에서 우려되는 변이체와 관련된 돌연변이가 있는 10개의 SARS-CoV-2 계통을 설명합니다. 베닌 유래 SARS-CoV-2 균주는 환자보다 백신 유래 항체에 의해 더 효율적으로 중화되어 아프리카에서 백신 접종을 가속화했습니다.