Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has the potential for rapid transmission in congregate settings. We describe the multidisciplinary response to an outbreak of coronavirus disease (COVID-19) in a large homeless shelter in Chicago, Illinois, USA. The response to the outbreak included 4 rounds of mass PCR testing of all staff and residents and subsequent isolation of persons who tested positive for SARS-CoV-2. We further describe the dynamics of the shelter outbreak by fitting a modified susceptible-exposed-infectious-recovered compartmental model incorporating the widespread SARS-CoV-2 testing and isolation measures implemented in this shelter. Our model demonstrates that rapid transmission of COVID-19 in the shelter occurred before the outbreak was detected; rates of transmission declined after widespread testing and isolation measures were put in place. Overall, we demonstrate the feasibility of mass PCR testing and isolation in congregate settings and suggest the necessity of prompt response to suspected COVID-19 outbreaks in homeless shelters.
【저자키워드】 COVID-19, coronavirus disease, severe acute respiratory syndrome coronavirus 2, viruses, respiratory infections, zoonoses, SARS-CoV-2, Illinois, reproductive number, SEIR model, United States, transmission dynamic, homeless shelter, congregate setting, Chicago, 【초록키워드】 coronavirus disease, severe acute respiratory syndrome coronavirus 2, coronavirus, feasibility, Transmission, severe acute respiratory syndrome Coronavirus, PCR testing, COVID-19 outbreak, SARS-CoV-2 testing, outbreak, Isolation, compartmental model, respiratory, USA, homeless shelter, Chicago, acute respiratory syndrome, acute respiratory syndrome coronavirus, measure, positive, widespread, tested, occurred, subsequent, declined, 【제목키워드】 Dynamics, USA, homeless shelter,