We estimated SARS-CoV-2 vaccine effectiveness against onward transmission by comparing secondary attack rates among household members for vaccinated and unvaccinated index cases, based on source and contact tracing data collected when the Delta variant was dominant. Effectiveness of full vaccination of the index case against transmission to unvaccinated and fully vaccinated household contacts, respectively, was 63% (95% confidence interval (CI): 46–75) and 40% (95% CI: 20–54), in addition to the direct protection of vaccination of contacts against infection.
All Keywords
【저자키워드】 COVID-19, SARS-CoV-2, Transmission, household study, vaccine effectiveness, 【초록키워드】 vaccination, Infection, Contact tracing, delta variant, SARS-CoV-2 vaccine, secondary attack rate, Effectiveness, household contacts, Contact, index case, attack rates, 95% CI, 95% confidence interval, index cases, onward transmission, dominant, collected, addition, 【제목키워드】 B.1.617.2, SARS-CoV-2 transmission, Effectiveness, household contact, Netherlands,
【저자키워드】 COVID-19, SARS-CoV-2, Transmission, household study, vaccine effectiveness, 【초록키워드】 vaccination, Infection, Contact tracing, delta variant, SARS-CoV-2 vaccine, secondary attack rate, Effectiveness, household contacts, Contact, index case, attack rates, 95% CI, 95% confidence interval, index cases, onward transmission, dominant, collected, addition, 【제목키워드】 B.1.617.2, SARS-CoV-2 transmission, Effectiveness, household contact, Netherlands,
델타 변이가 우세할 때 수집된 출처 및 접촉자 추적 데이터를 기반으로 예방접종 지수 사례와 백신 접종하지 않은 지수 사례에 대한 가구 구성원 간의 2차 공격 비율을 비교하여 이후 전파에 대한 SARS-CoV-2 백신 효과를 추정했습니다. 백신 접종을 하지 않은 가족과 완전히 예방 접종을 받은 가족 접촉자에게 전파되는 지수 사례의 완전 예방 접종 효과는 각각 63%(95% 신뢰 구간(CI): 46-75)와 40%(95% CI: 20-54)였습니다. 감염에 대한 접촉자의 예방 접종을 직접 보호하는 것 외에도.