The globally inimitable and unremitting outbreak of COVID-19 infection confirmed the emergency need for critical detection of human coronavirus infections. Laboratory diagnostic tests and imaging modalities are two test groups used for the detection of COVID-19. Nowadays, real-time polymerase chain reaction (RT-PCR) and computed tomography (CT) have been frequently utilized in the clinic. Some limitations that confront with these tests are false-negative results, tests redone for follow-up procedure, high cost, and unable to do for all patients. To overcome these limitations, modified and alternative tests must be considered. Among these tests, RdRp/Hel RT-PCR assay had the lowest diagnostic limitation and highest sensitivity and specificity for the detection of SARS-CoV-2 RNA in both respiratory tract and nonrespiratory tract clinical specimens. On the other hand, lung ultrasound (LUS) and magnetic resonance imaging (MRI) are CT-alternative imaging modalities for the management, screening, and follow-up of COVID-19 patients.
【초록키워드】 COVID-19, magnetic resonance imaging, diagnostic test, diagnostic, lung, RT-PCR, MRI, Computed tomography, Coronavirus infections, polymerase chain reaction, Sensitivity and specificity, COVID-19 infection, outbreak, diagnostic tests, management, real-time polymerase chain reaction, RdRP, SARS-CoV-2 RNA, Follow-up, respiratory tract, respiratory, false-negative results, group, Critical, false-negative, specimens, RT-PCR assay, patients, COVID-19 patients, Chain Reaction, imaging modalities, clinic, limitation, limitations, polymerase chain, lowest, human coronavirus, highest, overcome, 【제목키워드】 review, Test, imaging, literature, routine, modality, suggestion, insight, New,