Nutraceutical Approach to Preventing Coronavirus Disease 2019 and Related ComplicationsImmunology Published on 2021-06-282022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, MERS, SARS, [키워드] 2019-nCoV addition approach Atypical caused China Chinese Complication COVID-19 COVID-19-related complication disease effective infected patients Infectious diseases Inflammation Novel coronavirus nutraceutical nutraceuticals pharmacological Pneumonia Preventing SARS-CoV-2 selected synthesis therapy Treatment WHO Wuhan [DOI] 10.3389/fimmu.2021.582556 PMC 바로가기 [Article Type] Immunology
COVID-19 laboratory diagnosis: comparative analysis of different RNA extraction methods for SARS-CoV-2 detection by two amplification protocolsCOVID-19 실험실 진단: 두 가지 증폭 프로토콜에 의한 SARS-CoV-2 검출을 위한 서로 다른 RNA 추출 방법의 비교 분석Article Published on 2021-06-252022-09-11 Journal: Revista do Instituto de Medicina Tropical de São [Category] SARS, 치료기술, 치료제, [키워드] 2019-nCoV affected amplification Analysis automated Brazil Chain Reaction COVID-19 COVID-19 diagnosis Diagnosis diagnosis of COVID-19 DNA Extract extracted RNA False-positive gold gold standard handling Laboratory laboratory diagnosis less Lucigen outbreak Pandemics polymerase chain polymerase chain reaction protocol protocols Quantitative Quantitative real-time polymerase chain reaction quantity Randomly reverse transcription RNA RNA extraction RNA-dependent RNA polymerase RT-qPCR RT-qPCR assays SARS-CoV-2 SARS-CoV-2 detection selected sensitivities sensitivity target gene tested were used [DOI] 10.1590/S1678-9946202163052 PMC 바로가기 [Article Type] Article
A high-throughput screen for TMPRSS2 expression identifies FDA-approved compounds that can limit SARS-CoV-2 entryTMPRSS2 발현을 위한 고처리량 스크린으로 SARS-CoV-2 진입을 제한할 수 있는 FDA 승인 화합물 식별Article Published on 2021-06-232022-09-10 Journal: Nature Communications [Category] MERS, SARS, 비임상, [키워드] 2019-nCoV ACE2 breath Cell cell entry cell surface receptor clinical trial Compound compounds Concentration concentrations coronavirus COVID-19 disease COVID-19 infection DCAF1 DDB1 Degradation dependent on drug E3 ubiquitin ligase Effect entry of SARS-CoV-2 epithelial cells expression global pandemic halofuginone help High-throughput screening homoharringtonine Host host protease host proteases human clinical trial human clinical trials Human plasma identify in vitro library limit lung epithelial cell modulate pathogenic coronavirus pharmacokinetic data proteasome Protein reduce reducing responsible SARS-CoV-2 SARS-CoV-2 entry SARS-CoV-2 glycoprotein SARS-COV-2 infection Screen Serine serine protease serine protease TMPRSS2 small molecule Small molecules spike stability surface expression surface receptor the cell TMPRSS2 TMPRSS2 expression TMPRSS2 level TMPRSS2 levels TMPRSS2 protein [DOI] 10.1038/s41467-021-24156-y PMC 바로가기 [Article Type] Article
Understanding COVID-19 Epidemiology and Implications for Control: The Experience from a Greek Semi-Closed CommunityArticle Published on 2021-06-232022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] 2019-nCoV Abbott age antibody antibody test result Antibody testing Antigen antigen detection Architect Asymptomatic Community coronavirus correlation COVID-19 evaluate experience functional antibody responses Greece Hospitalization IgG Immunity Infection lockdowns natural immune response pandemic participant Patient Population positive predicted ranged Rapid SARS-CoV-2 semi-closed community serology Seroprevalence Serosurvey Sociodemographic study population susceptible symptomatic and asymptomatic Test tested the SARS-CoV-2 thresholds Total understanding USA was used were used [DOI] 10.3390/jcm10132765 PMC 바로가기 [Article Type] Article
The Psychological Effect of Forming WeChat Groups Between Medical Staff and Patients With COVID-19Public Health Published on 2021-06-232022-10-31 Journal: Frontiers in Public Health [Category] COVID-19, MERS, SARS, [키워드] 2019-nCoV Admission both group communication Compliance concerning conducted control group coronavirus disease COVID-19 discharge disease response Effect Establishing experimental group Forming group groups HADS Health Education Hospital stay medical staff negative Patient patients patients with COVID-19 Pneumonia positive promoted psychological care Psychological intervention Satisfaction scale schedule statistically significant Treatment two group WeChat WeChat group [DOI] 10.3389/fpubh.2021.586465 PMC 바로가기 [Article Type] Public Health
Toujie Quwen granule used with conventional western therapy for coronavirus disease 2019 A protocol for systematic review and meta-analysisCoronavirus Disease 2019에 대한 기존의 서양 요법과 함께 사용되는 Toujie Quwen 과립은 체계적인 검토 및 메타 분석을위한 프로토콜3800 Published on 2021-06-182022-08-31 Journal: Medicine [Category] meta-analysis, SARS, 치료제, [키워드] 2019 novel coronavirus 2019-nCoV Analysis assessment CBM Chinese Clinical studies clinical study clinical trial CNKI Cochrane Library conducted Controlled trial controlled trials coronavirus disease Coronavirus disease 2019 COVID-19 database development Efficacy and safety English Epidemic Evidence exclusion criteria include Inclusion inclusion and exclusion criteria Infectious disease International Meta-analysis Novel coronavirus platform protocol Randomized controlled trial RCTs registration number researcher searched statistical analysis systematic review therapy therapy for COVID-19 Toujie Quwen granule used to evaluate VIP Web of Science [DOI] 10.1097/MD.0000000000026370 PMC 바로가기 [Article Type] 3800
nCoV-2019 infection induced neurological outcome and manifestation, linking its historical ancestor SARS-CoV and MERS-CoV: a systematic review and meta-analysisArticle Published on 2021-06-182022-10-29 Journal: Scientific Reports [Category] COVID-19, MERS, [키워드] 2019-nCoV addition Analysis analyzed article Case report clinical trials clinician collected correlated COVID-19 COVID-19 patient COVID-19 positive patient COVID-19 positive patients criteria cross cross-sectional cross-sectional study cumulative disease event headache help heterogeneity identify Infection lack management manifestation Manifestations mechanism MedCalc Meningitis MERS MERS-CoV Meta-analysis nCOV-2019 nervous system Neurologic impairment neurological Neurological involvement neurological manifestation neurological sign Neurological symptom NEUROLOGY observational study outcome pandemic Pandemics pathogenic Patient patients present presenting Prevalence proportion reported SARS-CoV screened searched Seizure severity Signs and symptoms Standard Symptom symptomatic systematic review was used [DOI] 10.1038/s41598-021-92188-x PMC 바로가기 [Article Type] Article
Association of Gender With Outcomes in Hospitalized Patients With 2019-nCoV Infection in WuhanPublic Health Published on 2021-06-152022-10-31 Journal: Frontiers in Public Health [Category] COVID-19, MERS, SARS, [키워드] 2019-nCoV 2019-nCoV infection Analysis Anxiety association C-reactive protein Care chronic disease Clinical characteristics Clinical outcome collected Depression disease outcome disease severity dry cough Female patients Gender general condition incidence information male medical records men pandemic participant Patient Prevent Psychological psychological situation reduce response risk self-report measure severe pneumonia significantly higher smoking Stress Union Hospital women Wuhan [DOI] 10.3389/fpubh.2021.619482 PMC 바로가기 [Article Type] Public Health
Sleep in Older Adults and Its Possible Relations With COVID-19Neuroscience Published on 2021-06-112022-10-31 Journal: Frontiers in Aging Neuroscience [Category] COVID-19, [키워드] 2019-nCoV Adults affecting change characterized Corona virus Course COVID-19 COVID-19 pandemic COVID-19 prognosis elderly explain Factor greater Insomnia intrinsic latency likelihood novel corona virus obstructive sleep apnea Older older population outcomes predisposition Prevalence quarantine reduced relation Research risk SARS-CoV-2 Severe case Sleep sleep apnea sleep deprivation sleep disorder Sleep disturbance social isolation suggested with COVID-19 [DOI] 10.3389/fnagi.2021.647875 PMC 바로가기 [Article Type] Neuroscience
Analytical and Clinical Evaluation of “AccuPower SARS-CoV-2 Multiplex RT-PCR kit (Bioneer, South Korea)” and “Allplex 2019-nCoV Assay (Seegene, South Korea)” for SARS-CoV-2 RT-PCR Diagnosis: Korean CDC EUA as a Quality Control Proxy for Developing CountriesSARS-CoV-2 RT-PCR 진단을 위한 “AccuPower SARS-CoV-2 Multiplex RT-PCR kit (Bioneer, Korea)” 및 “Allplex 2019-nCoV Assay (Seegene, South Korea)”의 분석 및 임상 평가: 한국어 개발도상국을 위한 품질 관리 대리인으로서 CDC EUACellular and Infection Microbiology Published on 2021-06-102022-09-11 Journal: Frontiers in Cellular and Infection Microbiology [Category] MERS, SARS, 치료기술, [키워드] 2019-nCoV agency analytical sensitivity authorization Bioneer CDC clinical clinical evaluation Control country Developing developing countries Diagnosis Emergency Emergency use authorization EUA evaluated FDA gold gold standard Korean lack limit of detection market Multiple objective protocol Quality Quality control Result RT-PCR RT-PCR kit RT-qPCR SARS-CoV-2 SARS-CoV-2 RT-PCR Seegene sensitivity South South America South Korea Support [DOI] 10.3389/fcimb.2021.630552 PMC 바로가기 [Article Type] Cellular and Infection Microbiology