Considering epitopes conservity in targeting SARS-CoV-2 mutations in variants: a novel immunoinformatics approach to vaccine design변이체에서 SARS-CoV-2 돌연변이 표적화에서 에피토프 보존성 고려: 백신 설계에 대한 새로운 면역정보학 접근Article Published on 2022-08-182022-09-11 Journal: Scientific Reports [Category] SARS, 변종, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus adaptive Adaptive immunity antibody antigenicity approach Avian flu calculated collected conserved Coronavirus-2 database Developing Efficacy epitope Epitopes event flu ideal identify IEDB immune Immune Epitope Database Immunity immunodominant immunogenicity immunoinformatics mutated Mutation mutations neutralization pathogenicity platform predicted preference provide reduce Region SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 genomes SARS-CoV-2 mutation selected Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus-2 Shannon entropy similarity solution technique Vaccine design Vaccines variant variants virulence virus viruses [DOI] 10.1038/s41598-022-18152-5 PMC 바로가기 [Article Type] Article
Evaluation of SARS-CoV-2 transmission in COVID-19 isolation wards: On-site sampling and numerical analysisCOVID-19 격리 병동에서 SARS-CoV-2 전파 평가: 현장 샘플링 및 수치 분석Article Published on 2022-08-152022-09-11 Journal: Journal of hazardous materials [Category] COVID19(2023년), SARS, 치료기술, [키워드] accumulated aerosol aerosol transmission Aerosols Analysis calculated CFD collected Computational fluid dynamics Computational Fluid Dynamics (CFD) correlated COVID-19 deposition dispersion effective evaluated Hong Kong indoor environment Intervention investigated Isolation measure Numerical Analysis Particle Particles positive positive rate Prince reducing RT-PCR RT-PCR test SARS-CoV-2 SARS-CoV-2 RNA SARS-CoV-2 transmission Spread Testing the SARS-CoV-2 Transmission transmission of SARS-CoV-2 Ventilation virus [DOI] 10.1016/j.jhazmat.2022.129152 PMC 바로가기 [Article Type] Article
Transmissibility, hospitalization, and intensive care admissions due to omicron compared to delta variants of SARS-CoV-2 in Catalonia: A cohort study and ecological analysisArticle Published on 2022-08-122022-11-15 Journal: Frontiers in Public Health [Category] SARS, 변종, 치료기술, [키워드] 95% CI 95% confidence interval addition Admission admitted to ICU age Analysis average calculate calculated cohort study cohorts COVID-19 decrease delta variant dominant dropped ecological Ecological study groups hospital Hospital admissions Hospitalization Hospitalized ICU ICU admission ICU admissions increase in independent intensive care intrinsic Local omicron Omicron variant performed population-based cohort positive primary care proportion rate ratio reduced reduction reduction in required risk SARS-CoV-2 severity severity and vaccination status Severity of infection stratified substitution model. System Transmissibility vaccination variant [DOI] 10.3389/fpubh.2022.961030 PMC 바로가기
Long-term cardiovascular outcomes in COVID-19 survivors among non-vaccinated population: A retrospective cohort study from the TriNetX US collaborative networksResearch article Published on 2022-08-112022-10-05 Journal: EClinicalMedicine [Category] 치료기술, [키워드] age Analysis arrhythmia Atrial fibrillation calculated cardiac disorders Cardiomyopathy cardiovascular disease Cardiovascular health Cardiovascular outcomes cerebrovascular diseases CIs Cohort conducted confidence controls COVID-19 COVID-19 test disease disorder disorders Elite endpoints female finding Follow-up Fund funding hazard heart failure Hospitalization HRs increased risk Infection Inflammatory initiated Inpatient interval male Mortality myocarditis network Non-COVID-19 outcome outcomes outpatients participant Patient performed Post-acute sequelae Probability Program public welfare recruited Research retrospective cohort study risk SARS-COV-2 infection SARS-CoV-2 testing scientist severity of COVID-19 Sex stratified stroke subgroup analysis survival survivor Survivors thromboembolic TriNetX two group [DOI] 10.1016/j.eclinm.2022.101619 [Article Type] Research article
Relative effectiveness of booster vs. 2-dose mRNA Covid-19 vaccination in the Veterans Health Administration: Self-controlled risk interval analysis재향 군인 보건국에서 부스터 대 2-용량 mRNA 코비드-19 백신 접종의 상대적 효과: 자가 통제 위험 간격 분석Article Published on 2022-08-052022-09-11 Journal: Vaccine [Category] COVID19(2023년), SARS, 변종, [키워드] (Maximum 6): Covid-19 age Analysis Antigen approach booster booster vaccination calculate calculated conducted confounders Delta effective Effectiveness exposure Gain groups health administration identify Immunity individual Logistic regression main analysis maximum mRNA odds of infection Odds ratio Odds ratios omicron Omicron variants positive positive PCR Positive test predominant relative risk SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 test Self-controlled case series Sensitivity analyses sensitivity analysis Stratification Study design vaccination Vaccine vaccine effectiveness variant veteran warehouse [DOI] 10.1016/j.vaccine.2022.06.047 PMC 바로가기 [Article Type] Article
SARS-CoV-2 RT-PCR positivity in relation to clinical and demographic characteristics in residents of border quarantine centres, Khyber Pakhtunkhwa, Pakistan: a prospective cohort study파키스탄 Khyber Pakhtunkhwa 국경 검역소 거주자의 임상 및 인구 통계학적 특성과 관련된 SARS-CoV-2 RT-PCR 양성: 전향적 코호트 연구Article Published on 2022-08-052022-09-11 Journal: Transactions of the Royal Society of Tropical Medi [Category] SARS, 변종, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 adjusted odds ratio adjusted odds ratios age Analysis association Asymptomatic asymptomatic infection calculate calculated Chain Reaction conducted coronavirus COVID-19 demographic characteristics driver effective groups hazard ratio hazard ratios healthy higher odd higher odds individual individuals Infection International Isolation Kaplan-Meier Kaplan-Meier curve Kaplan-Meier curves less Logistic regression Mantel-Haenszel Measures Older age Pakistan Period period prevalence polymerase chain polymerase chain reaction positive pre-symptomatic Prevalence primary source prospective cohort study quarantine remained reverse transcription SARS-CoV-2 SARS-CoV-2 RT-PCR Sex significantly tested Time-to-event Transmission TTE variants was used were assessed [DOI] 10.1093/trstmh/trac057 PMC 바로가기 [Article Type] Article
Preterm birth among pregnant persons with severe acute respiratory syndrome Coronavirus 2 infection Research Published on 2022-08-042022-10-05 Journal: Journal of perinatology : official journal of the [Category] COVID19(2023년), SARS, 치료기술, [키워드] acute respiratory syndrome adjusted age analyzed asymptomatic infection calculated can be used Clinical practice complications coronavirus 2 COVID-19 Critical examined Illness severity increased risk Infection Medical conditions Mild moderate-to-severe COVID-19 objective Pregnancy pregnant Preterm birth Result risk risk ratio SARS-COV-2 infection selected stratified The United States vaccination [DOI] 10.1038/s41372-022-01467-6 [Article Type] Research
Recurrent SARS-CoV-2 Serology Testing and Pandemic Anxiety: A Study of Pediatric Healthcare Workers재발성 SARS-CoV-2 혈청 검사 및 유행성 불안: 소아 의료 종사자에 대한 연구Article Published on 2022-08-032022-09-12 Journal: International Journal of Environmental Research an [Category] SARS, 진단, [키워드] analyses Analysis antibody Antibody testing Anxiety asked baseline calculated change changes in clinically conducted COVID-19 decrease demographics Department Emergency examined female HCW HCWs healthcare worker indicated less Limited Logistic regression longitudinal cohort study male Nurse participant pediatric pediatrics performed positive test result Recurrent repeated repeated measure repeated measures reported routine SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV-2 antibody testing SARS-CoV-2 testing serology testing significantly higher Testing the disease worker [DOI] 10.3390/ijerph19159562 PMC 바로가기 [Article Type] Article
Effects of cardiopulmonary bypass on immunoglobulin G antibody titres after SARS-CoV2 vaccinationObservational Study Published on 2022-08-032022-10-05 Journal: Interactive cardiovascular and thoracic surgery [Category] SARS, 임상, 진단, [키워드] acute respiratory syndrome antibody Antibody titre BNT162b2 calculated Cardiopulmonary cardiopulmonary bypass cardiovascular disease coronavirus Coronavirus disease 2019 decrease disease Effect effective group IgG IgG antibody Immunoglobulin Infection investigated Moderna mRNA vaccine mRNA-1273 Patient Pfizer/BioNTech preoperative preserved prospective observational study required SARS-CoV2 severe acute respiratory syndrome coronavirus 2 significantly significantly lower surgical the receptor-binding domain titre U/mL vaccination vaccination schedule Vaccine was measured while [DOI] 10.1093/icvts/ivac123 PMC 바로가기 [Article Type] Observational Study
CoVM 2: Molecular Biological Data Integration of SARS-CoV-2 Proteins in a Macro-to-Micro MethodCoVM 2: 거시적 방법에서 SARS-CoV-2 단백질의 분자 생물학적 데이터 통합Article Published on 2022-08-022022-09-11 Journal: Biomolecules [Category] SARS, 변종, 치료기술, [키워드] accumulated addition Affect analyzed association B.1.617.2 binding binding affinity binding state Biological calculated causative agent changes in collected COVID-19 COVID-19 pandemic crystal structure crystal structures Data integration Delta docking examined glycoprotein human proteins human receptor human receptors information integration Interaction lack macro molecular Molecular biology Multiple Mutation omicron physical PPI network Protein protein interaction protein structure protein structure docking protein-protein interaction public health receptor protein Research S protein S proteins SARS-CoV-2 SARS-CoV-2 protein SARS-CoV-2 proteins selected sequence strain Structure structures variant variants Viral protein Viral proteins virus–host interactions [DOI] 10.3390/biom12081067 PMC 바로가기 [Article Type] Article