Diversity of Coronaviruses in Wild Representatives of the Aves Class in PolandArticle Published on 2021-07-292022-10-28 Journal: Viruses [Category] Coronavirus, [키워드] Anseriforme antibody Charadriiforme class coronavirus Coronaviruses detection rate Diversity duck Galliforme Gruiforme host range Infectious Bronchitis Virus Lineage majority MOST performed Phylogenetic Poland Population Prevalence reservoir sera SEROLOGICAL STUDY Suliforme virus wild birds [DOI] 10.3390/v13081497 PMC 바로가기 [Article Type] Article
Impact of Disease-Modifying Treatments of Multiple Sclerosis on Anti-SARS-CoV-2 Antibodies: An Observational Study다발성 경화증의 질병 조절 치료가 항 SARS-CoV-2 항체에 미치는 영향: 관찰 연구Observational Study Published on 2021-07-282022-09-12 Journal: Neurology® neuroimmunology & neuroinflammation [Category] SARS, 임상, 진단, [키워드] acute respiratory syndrome adjusted Analysis anti-CD20 anti-SARS-CoV-2 anti-SARS-CoV-2 vaccination benefit class classification coronavirus coronavirus disease correlated COVID-19 COVID-19 severity evaluated Evidence humoral Humoral response IgG Immunoglobulin Impact Infection Interferon β-1a mAb monoclonal antibody Multiple multiple sclerosis Patient patients treated primary endpoint provide receiving recurrent infection risk SARS-CoV-2 SARS-CoV-2 PCR sclerosis serology Treatment vaccination [DOI] 10.1212/NXI.0000000000001055 PMC 바로가기 [Article Type] Observational Study
Variation in SARS-CoV-2 seroprevalence across districts, schools and classes: baseline measurements from a cohort of primary and secondary school children in Switzerland학군, 학교 및 학급 전반에 걸친 SARS-CoV-2 혈청 유병률의 변화: 스위스의 초등 및 중등 학생 집단의 기준선 측정Article Published on 2021-07-262022-09-11 Journal: BMJ Open [Category] SARS, 진단, 치료기술, [키워드] 95% CI Adults age baseline Baseline measurement Baseline measurements child health children Ciao class Clustering Cohort Community community child health compatible symptoms Corona coronavirus credible interval CrI cumulative detect determine District Epidemiology epitope Epitopes Follow-up Frequency IgA IgG IgM immunisation Immunoglobulin Infection infection control Infectious disease longitudinal cohort study median median age outcome paediatric infectious disease & registration number reported SARS-CoV-2 SARS-CoV-2 seroprevalence School school children Schools Self-reported symptoms sensitive seronegative seropositive Seropositivity Seroprevalence spike stratified Switzerland Symptom Symptoms tested Transmission Variation Virology [DOI] 10.1136/bmjopen-2020-047483 PMC 바로가기 [Article Type] Article
Influence of HLA Class II Polymorphism on Predicted Cellular Immunity Against SARS-CoV-2 at the Population and Individual LevelImmunology Published on 2021-07-192022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, SARS, [키워드] adaptive Against anti-SARS-CoV-2 CD4+ T-cells cellular immunity class Clinical outcome COVID-19 development FIVE Genotype groups High-resolution HLA HLA class II Human Leukocyte Antigens identify Immunity individual individual level influence inter-individual Level peptide polymorphism Population population level populations predicted protective immunity SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 proteins T-cells unlikely vaccination Variability viral peptides [DOI] 10.3389/fimmu.2021.669357 PMC 바로가기 [Article Type] Immunology
Ocrelizumab Extended Interval Dosing in Multiple Sclerosis in Times of COVID-19COVID-19 시기에 다발성 경화증에서 Ocrelizumab 연장된 간격 투여Observational Study Published on 2021-07-142022-09-11 Journal: Neurology® neuroimmunology & neuroinflammation [Category] 바이오마커, 임상, 진단, [키워드] accompanied association B-cell both groups CD19 class classification clinical clinical consequence clinical consequences Cohort control group coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 pandemic defined disability Disease activity dose Dosing Effectiveness evaluate evaluated Evidence evidence of Extended extended interval Follow-up in both group interquartile range interval Logistic regression median MRI multicenter cohort study Multiple multiple sclerosis multivariate multivariate logistic regression no evidence of Ocrelizumab pandemic Patient potential risk progression provide Relapsing-Remitting Multiple Sclerosis remained retrospective sclerosis stability standard interval Support time treatment regimen [DOI] 10.1212/NXI.0000000000001035 PMC 바로가기 [Article Type] Observational Study
Adaptation of the endemic coronaviruses HCoV-OC43 and HCoV-229E to the human hostResearch Article Published on 2021-06-242022-10-28 Journal: Virus Evolution [Category] COVID-19, [키워드] accessory proteins accompanied accumulated adaptation antigenic antigenic drift applied approach binding affinity both virus both viruses cellular receptor class coronavirus Coronaviruses driven by Endemic endemic coronavirus event Evolution evolutionary dynamics generate HCoV-229E HCoV-HKU1 HCoV-NL63 HCoV-OC43 HCoV-OC43 spike Hemagglutinin-esterase higher affinity highly pathogenic human cell human host human populations Hypothesis I, II Immunity indicated Infection Like Limited genetic diversity Membrane proteins molecular dating molecular evolution much higher Positive selection Protein RBD RBDs Receptor binding Result SARS-CoV-2 evolution selected selective Spike protein strain suggested targets the RBD the receptor-binding domain the spike protein time interval trajectory undergo virus zoonotic zoonotic origins [DOI] 10.1093/ve/veab061 PMC 바로가기 [Article Type] Research Article
Soluble Neuropilin-1 Response to Hypoglycemia in Type 2 Diabetes: Increased Risk or Protection in SARS-CoV-2 Infection?Endocrinology Published on 2021-06-232022-10-31 Journal: Frontiers in Endocrinology [Category] COVID-19, MERS, SARS, [키워드] ACE ACE inhibitors ACE2 activated ADAM9 AGT Angiotensin-converting enzyme aptamer case-control study Cell class clinical co-expressed cofactor Control controls COVID-19 determine disintegrin elevated endothelial ENhance enzyme Glucose growth factor hypoglycemia Increased increased risk inhibitor Ligand mechanism Neuropilin-1 no difference not differ not different NRP1 plasma plasma protein promote protection Protective proteolytic RAS Registration remained REN response Result SARS-CoV-2 SARS-CoV-2 coronavirus SARS-COV-2 infection SEMA3A serum slow stratified Stress subject subsequent System T2D therapy Type type 2 diabete type 2 diabetes VEGF [DOI] 10.3389/fendo.2021.665134 PMC 바로가기 [Article Type] Endocrinology
SARS-CoV-2 tests in occupational settings: what you look for is what you get직업 환경에서의 SARS-CoV-2 검사: 찾는 것이 곧 얻는 것Article Published on 2021-06-152022-09-11 Journal: La Medicina del lavoro [Category] SARS, 변종, 치료기술, [키워드] antibody asymptomatic subjects China class comparable COVID-19 diagnose diagnostic Factor identify imperative individual Infection Interpretation Laboratory New coronavirus occupational medicine outbreak pandemic SARS-CoV-2 test screening test serological test set off Spread variants Viral antigen viral antigens viral evolution workplace safety [DOI] 10.23749/mdl.v112i3.11472 PMC 바로가기 [Article Type] Article
How Children Are Protected From COVID-19? A Historical, Clinical, and Pathophysiological Approach to Address COVID-19 SusceptibilityCOVID-19로부터 어린이를 보호하는 방법은 무엇입니까? COVID-19 감수성을 해결하기 위한 역사적, 임상적, 병태생리학적 접근Immunology Published on 2021-06-112022-09-11 Journal: Frontiers in Immunology [Category] MERS, SARS, 유전자 메커니즘, 진단, [키워드] accompanied ACE-2 receptor acute respiratory syndrome acute respiratory syndrome coronavirus adaptive Adaptive immunity address affected autoimmune disorder B1 B cells Bacteria Bacterial bacterial pathogen Bacterial pathogens Behcet’s disease children China class clinical coronavirus coronavirus disease Coronavirus disease 2019 country COVID-19 Defense disease exhibiting favor genetics IgM Immunity Immunoglobulin innate immune Iran Italy Kawasaki-like disease mechanism membrane membranes molecular mechanisms Mortality Native natural IgM Neonate Neonates neutralize oxygen Pathogens Patient Pediatric patient Pediatric patients Prevalence progression reactive oxygen species reactive oxygen specy Recognition Region respiratory SARS-CoV-2 selective self-antigens severe acute respiratory syndrome Coronavirus severe COVID-19 silk road South Spread stressed cells Symptom the epidemic thrombosis Trigger Turkey Vasculitis Viral viral envelope virus [DOI] 10.3389/fimmu.2021.646894 PMC 바로가기 [Article Type] Immunology
Detailed Multiplex Analysis of SARS-CoV-2 Specific Antibodies in COVID-19 DiseaseCOVID-19 질병에서 SARS-CoV-2 특이적 항체의 상세한 다중 분석Immunology Published on 2021-06-102022-09-11 Journal: Frontiers in Immunology [Category] MERS, SARS, 진단, 치료법, [키워드] Analysis analyzed antibodies antibody antibody isotype antibody isotypes Antibody Response calibrated calibration class COVID-19 disease Elecsy Elecsys Hospital admission IgA IgA antibodies IgA antibody IgA level IgA levels IgG IgM Immunological response include initial intensive care multiple antigen multiple antigens multiplex novel vaccines nucleocapsid protein Nucleocapsid proteins occur outpatients patients positive RBD Receptor binding domain Roche S1 IgG SARS-CoV-2 SARS-CoV-2 virus sensitivity significant increase significantly Specific specificity switching the antibody response the SARS-CoV-2 virus Vaccines [DOI] 10.3389/fimmu.2021.695230 PMC 바로가기 [Article Type] Immunology