NETosis and Nucleosome Biomarkers in Septic Shock and Critical COVID-19 Patients: An Observational Study패혈성 쇼크 및 심각한 COVID-19 환자의 NETosis 및 뉴클레오솜 바이오마커: 관찰 연구Observational Study Published on 2022-07-272022-09-11 Journal: Biomolecules [Category] MERS, 바이오마커, 임상, [키워드] alternative Biomarker Biomarkers cell death conditions Control control subject COVID-19 Critical critical COVID-19 patient critical COVID-19 patients Defense discrimination disease severity evaluate extracellular trap histone ICU Infection Intact intensive care intensive care unit marker matched control mechanism microorganisms MPO myeloperoxidase NET NETosis NETs NETs’ formation neutrophil neutrophil activation neutrophil count Neutrophil elastase Neutrophil extracellular traps Neutrophils normalization Nucleosome nucleosomes P -value p -values patient cohort patients phagocytosis recruited Result SARS-CoV-2 septic Septic shock Significant significant differences Spread subject were measured [DOI] 10.3390/biom12081038 PMC 바로가기 [Article Type] Observational Study
Assessing Telemedicine Efficiency in Follow-up Care With Video Consultations for Patients in Orthopedic and Trauma Surgery in Germany: Randomized Controlled TrialRandomized Controlled Trial Published on 2022-07-272022-10-05 Journal: Journal of Medical Internet Research [Category] 임상, [키워드] Analysis Assessing Care change clinical collected conditions conducted consultation control group Controlled country COVID-19 pandemic disadvantage Efficiency enrolled Follow-up Germany group Health help indicated mitigate mobile phone no significant difference orthopedic Patient Patient satisfaction physician problems Questionnaires Randomized controlled trial Satisfaction statistically significant subsequent surgery Telemedicine trauma Trauma surgery university hospital video consultations. [DOI] 10.2196/36996 PMC 바로가기 [Article Type] Randomized Controlled Trial
Comparison of Surface Persistence of SARS-CoV-2 Alpha and Delta Variants on Stainless Steel at 4°C and 24°C4°C 및 24°C에서 스테인리스강에 대한 SARS-CoV-2 알파 및 델타 변이체의 표면 지속성 비교Article Published on 2022-07-262022-09-11 Journal: Applied and Environmental Microbiology [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] Aerosols Alpha alpha and delta variants Alpha variant both virus both viruses conditions conducted contact with contaminated surface contaminated surfaces COVID-19 Delta delta variant detectable droplet Evidence fomites Human implication in some Intervention investigated log MOST occur persistence provide reduction reductions Region RNA RNA virus SARS-CoV-2 SARS-CoV-2 variants stability stainless steel steel Support surface surface persistence surface stability survival survived temperature through contact transfer Transmission transmission of SARS-CoV-2 variant winter transmission. [DOI] 10.1128/aem.00764-22 PMC 바로가기 [Article Type] Article
Deep Learning-Based Networks for Detecting Anomalies in Chest X-Rays흉부 X선에서 이상 징후를 감지하기 위한 딥 러닝 기반 네트워크Article Published on 2022-07-232022-09-11 Journal: BioMed Research International [Category] COVID19(2023년), SARS, 치료기술, [키워드] Accuracy ad hoc anomalies Anomaly approach approaches Chest chest X-ray chest X-rays Classifier classifiers conditions Critical data set database deep deep learning demonstrated detect Diagnosis eliminating evaluated example imaging test investigated knowledge network Pathologies pathology performed Pneumonia popularity professional Radiological examinations Research starting tested transfer X-ray [DOI] 10.1155/2022/7833516 PMC 바로가기 [Article Type] Article
Effectiveness of 2, 3, and 4 COVID-19 mRNA Vaccine Doses Among Immunocompetent Adults During Periods when SARS-CoV-2 Omicron BA.1 and BA.2/BA.2.12.1 Sublineages Predominated – VISION Network, 10 States, December 2021-June 2022SARS-CoV-2 Omicron BA.1 및 BA.2/BA.2.12.1 하위 계통이 우세한 기간 동안 면역적격 성인 중 2, 3 및 4 COVID-19 mRNA 백신 용량의 효과 - VISION Network, 10개 주, 2021년 12월 -2022년 6월Article Published on 2022-07-222022-09-11 Journal: Morbidity and Mortality Weekly Report [Category] COVID19(2023년), SARS, 변종, [키워드] 95% CI accounted B.1.1.529 BNT162b2 booster dose booster doses Care cause conditions COVID-19 COVID-19 case COVID-19 vaccine Diagnosis dose Effectiveness eligible estimate evade evaluate examined Hospitalization initial median moderate moderate to severe mRNA mRNA COVID-19 vaccine mRNA COVID-19 vaccines mRNA-1273 network omicron Omicron variant pattern Period Pfizer-BioNTech Prevent real-world data receipt receive reduced SARS-CoV-2 SARS-COV-2 infection severe COVID-19 the United State United States vaccination Vaccine-induced immunity variant virus [DOI] 10.15585/mmwr.mm7129e1 PMC 바로가기 [Article Type] Article
COVID-19 Associated Guillain-Barré Syndrome: A Report of Nine New Cases and a Review of the LiteratureCOVID-19 관련 길랑-바레 증후군: 9건의 신규 사례 보고 및 문헌 검토Review Published on 2022-07-222022-09-12 Journal: Medicina [Category] MERS, 진단, [키워드] Admission analyzed case sery causes characterized clinical Clinical features conditions conducted Course COVID-19 COVID-19 patient COVID-19 symptom Department Diagnosis died discharge dysfunction Guillain–Barrè syndrome Hospitalized Immune-mediated immunoglobulins Inflammatory intravenous literature literature review manifested mechanical ventilation mortality rate neurological NEUROLOGY New notable outcome Patient peripheral neuropathies plasma polyneuropathies positive Registered report required Respiratory failure review Romania Symptom Symptoms syndrome the mean Treatment variable [DOI] 10.3390/medicina58080977 PMC 바로가기 [Article Type] Review
Detection of neutralizing antibodies against multiple SARS-CoV-2 strains in dried blood spots using cell-free PCRCell-free PCR을 이용한 건조된 혈반에서 여러 SARS-CoV-2 균주에 대한 중화항체 검출Article Published on 2022-07-212022-09-11 Journal: Nature Communications [Category] COVID19(2023년), MERS, SARS, 변종, 진단, 치료기술, 치료법, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 age angiotensin binding conditions coronavirus detect detection dried blood spot Dried blood spots Efficacy Health help herd immunity human Angiotensin-converting enzyme Immunity inhibition multiplex Neutralization assay Neutralizing antibodies neutralizing antibody PCR real-time qPCR receptor protein respiratory SARS-CoV-2 SARS-CoV-2 strain sensitivity Serological assay serum severe acute respiratory syndrome Coronavirus specificity specimen Spike protein subunit vaccination vaccination rates Vaccine vaccine efficacy Viral viral spike protein waning immunity [DOI] 10.1038/s41467-022-31796-1 PMC 바로가기 [Article Type] Article
Causal Modeling to Mitigate Selection Bias and Unmeasured Confounding in Internet-Based Epidemiology of COVID-19: Model Development and ValidationCOVID-19의 인터넷 기반 역학에서 선택 편향과 측정되지 않은 교란을 완화하기 위한 인과 관계 모델링: 모델 개발 및 검증Article Published on 2022-07-212022-09-11 Journal: JMIR Public Health and Surveillance [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] age applied approach Bia bias Causal Causality collected Community compatibility conditions Confounding confounding factors COVID-19 COVID-19 symptoms Critical cumulative demographic characteristics demographics design detect determine develop development Diagnosis Epidemic epidemiologic research design epidemiological Epidemiological study Epidemiology estimate Health status household infection implementation Infection infection rate internal and external Mechanical mechanism method mitigate Model modeling MTurk New New York New York City omicron Omicron variants problem protocol public health Qualtrics recent reported Research Research design response Selection selection bia Selection bias sensitivity sensitivity analysis skewed state subject Surveillance the disease Threats utility validation Validity variant [DOI] 10.2196/31306 PMC 바로가기 [Article Type] Article
A comprehensive evaluation of the immune system response and type-I Interferon signaling pathway in hospitalized COVID-19 patients입원한 코로나19 환자의 면역 체계 반응 및 I형 인터페론 신호 전달 경로에 대한 종합 평가Article Published on 2022-07-162022-09-12 Journal: Cell Communication and Signaling : CCS [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] Abstract association autoantibody B lymphocyte CD4 CD8 conditions conducted COVID-19 COVID-19 pandemic COVID-19 patient COVID-19 patients cytokine decrease downstream dysregulation ELISA enrolled enzyme-linked immunosorbent evaluate evaluated expression expression level Factor flow cytometry Frequency healthy controls healthy individual hospitalized COVID-19 patient IFN-I IFN-I signaling IFN-α IFN-β IL-10 IL-17 IL-1β IL-6 illness Illness severity Immune cell immune system Immune-phenotype investigated IRF life-threatening material Mild Mild symptom NK cell NK cells Numerous Pathogenesis pathway Patient positive Protein protein levels Real-time PCR reduced Regulatory RNA SARS-CoV2 sera severity signaling molecule signaling molecules signaling pathway significant decrease Th17 TNF-α Treatment Treg Treg cell Vaccines virus [DOI] 10.1186/s12964-022-00903-6 PMC 바로가기 [Article Type] Article
Urban monitoring, evaluation and application of COVID-19 listed vaccine effectiveness: a health code blockchain studyCOVID-19 등재 백신 효과의 도시 모니터링, 평가 및 적용: 건강 코드 블록체인 연구Article Published on 2022-07-132022-09-11 Journal: BMJ Open [Category] 변종, [키워드] aggravate Algorithm analysed Analysis Asymptomatic average basic reproduction number calculate city Complete conditions Contact cooperation country COVID-19 decrease deviation Effectiveness eight ENhance epidemiological Epidemiological investigation Epidemiology evaluate greater Health Health policy herd immunity Immunity increase Incubation period index infection rate information measure MONITOR mutant virus not decreased outcome Patient Primary outcome Primary outcomes promote promoted proportion protective effect reduced regions respond second significantly Simulation statistical symptomatic the vaccine this system transmitted urban urban population vaccination vaccination rate Vaccination strategy Vaccine Vaccines variant Variation virus weight [DOI] 10.1136/bmjopen-2021-057281 PMC 바로가기 [Article Type] Article