Convalescent patients – Page 10 – Communicable Diseases Research

Identification of SARS-CoV-2 Nucleocapsid and Spike T-Cell Epitopes for Assessing T-Cell Immunity

Cellular Response to Infection

Published on 2020-12-212022-10-30
Journal: Journal of Virology [Category] COVID-19, MERS,

Neutralizing Antibody Responses to Severe Acute Respiratory Syndrome Coronavirus 2 in Coronavirus Disease 2019 Inpatients and Convalescent Patients

코로나 바이러스 질병 2019 입원 환자 및 회복기 환자의 중증 급성 호흡기 증후군 코로나 바이러스 2에 대한 중화 항체 반응

Article

Published on 2020-12-172022-09-11
Journal: Clinical Infectious Diseases: An Official Publicat [Category] MERS, SARS, 진단, 치료기술,

[키워드] 95% CI 95% confidence interval acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Analysis analyzed antibody Antibody titer Antiviral treatment blood sample Blood samples Clinical characteristics collected convalescent convalescent patient Convalescent patients coronavirus coronavirus 2 coronavirus disease Coronavirus disease 2019 COVID-19 different time point different time points disease early stage ELISA enzyme enzyme-linked immunosorbent enzyme-linked immunosorbent assay geometric mean geometric mean titer Inpatient multivariate Neutralization assay Neutralizing antibodies neutralizing antibody Neutralizing antibody titer pandemic Patient peaked reached remained respiratory response SARS-CoV-2 Seropositivity shown Vaccines
[DOI] 10.1093/cid/ciaa721 PMC 바로가기 [Article Type] Article

SARS-CoV-2 Epitopes Are Recognized by a Public and Diverse Repertoire of Human T Cell Receptors

SARS-CoV-2 에피토프는 인간 T 세포 수용체의 공개적이고 다양한 레퍼토리에 의해 인식됩니다

Article

Published on 2020-12-152022-09-12
Journal: Immunity [Category] MERS, SARS, 진단,

Clinical characteristics of 134 convalescent patients with COVID-19 in Guizhou, China

Research

Published on 2020-11-262022-10-28
Journal: Respiratory Research [Category] COVID-19,

[키워드] 2019 coronavirus disease age alanine aminotransferase analyzed Characteristics Chest CT children China clinical Clinical characteristics Clinical features Cohort Comorbidities convalescent patient Convalescent patients Coronavirus disease 2019 (COVID-19) COVID-19 COVID-19 patients develop diabetes discharged discharged patient disease disease severity elevated evaluate fibrosis Follow-up ground-glass opacity had more hospitalized patient hypertension IgG IgM antibody IQR laboratory data Limited Liver injury lymphocytopenia lymphopenia median men non-severe cases non-severe patients Older patchy Patient patients physician Pneumonia positive rate previous study radiological features rehabilitation Result Retrospective study severe cases severe COVID-19 patients Severe patient severe patients significant difference staff Thyroid Treatment with COVID-19 women
[DOI] 10.1186/s12931-020-01580-0 PMC 바로가기 [Article Type] Research

Immunological imprint of COVID‐19 on human peripheral blood leukocyte populations

인간 말초 혈액 백혈구 개체군에 대한 COVID-19의 면역학적 각인

Original Article

Published on 2020-11-222022-09-01
Journal: Allergy [Category] SARS, 진단, 치료법,

[키워드] activated Activation acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 adaptive addition antibody antibody levels B cells CD25 CD3 CD31 CD38 CD4 CD45 CD45RA CD8 Cell cells cellular Cellular immune response cellular immune responses central memory clinical immunology Cohort convalescent patient Convalescent patients coronavirus coronavirus disease Coronavirus disease 2019 correlated COVID‐19 COVID‐19 patient COVID‐19 patients determined by disease domain effector memory elevated ELISA expression flow cytometry FOXP3 healthy control HLA‐DR immune responses immune system immunological immunological change immunological changes immunosorbent Infection infections innate immune system investigated leukocyte population Lymphocytes Mild Mild disease multiparametric flow cytometry neutrophil Neutrophils nucleocapsid pandemic parameters Patient patients Peripheral blood qPCR Quantitative quantitative PCR RBD receptor receptor‐binding domain Recombination reduction reflected regression analysis respiratory responses Result SARS‐CoV‐2 SARS‐CoV‐2 infection SARS‑CoV2 SARS‐CoV‐2 sense sense of taste severe acute respiratory syndrome Coronavirus significantly Spike protein subject T cell T cells T regulatory cell T regulatory cells T‐cell Taste thymic emigrant thymic emigrants transitional B cell transitional B cells triggered Viral
[DOI] 10.1111/all.14647 PMC 바로가기 [Article Type] Original Article

The effect of meditative movement on the quality of life in patients recovering from COVID-19 A protocol for systematic review and meta-analysis

3800

Published on 2020-11-202022-10-30
Journal: Medicine [Category] COVID-19, SARS,

[키워드] Affect Analysis anorexia average Chest China Chinese clinical CNKI Cochrane Library Convalescent patients cough COVID-19 COVID-19 patient Data collection data extraction database diarrhea disease distress effective intervention eligible Evidence Google Scholar Hospitalization ICTRP identify IMPROVE Infrastructure Isolation journal limit literature majority management meditative movement mental health Meta-analysis Microsoft Excel Mortality myalgia nausea Novel coronavirus occurrence rate outbreak outcome OVID Patient patient with COVID-19 performed pharyngalgia physical Pneumonia Promoting protocol Quality of life Quantitative data recovering from COVID-19 registry rehabilitation patients service sputum Support Symptom symptomatic System systematic review Treatment treatment for COVID-19 Trial trials VIP vomiting while WHO
[DOI] 10.1097/MD.0000000000023225 PMC 바로가기 [Article Type] 3800

Engineered ACE2 receptor traps potently neutralize SARS-CoV-2

Biological Sciences

Published on 2020-11-102022-10-29
Journal: Proceedings of the National Academy of Sciences of [Category] COVID-19,

[키워드] ACE2 ACE2 receptor ACE2 variant acute respiratory syndrome addition Affinity maturation amino acid change Angiotensin-converting enzyme antibody antiviral therapeutics approach authentic SARS-CoV-2 virus backbone binding cells computational design convalescent patient Convalescent patients coronavirus Coronaviruses COVID-19 pandemic domain entry receptor faster flexible generate half-maximal inhibitory concentration host cells human immunoglobulin IC50s impair inactivated Infection infections lentivirus mechanism mutations neutralize neutralized neutralizing antibody offer other coronavirus Prevent Protein random mutagenesis RBD receptor Receptor binding Receptor binding domain receptor protein receptor trap respiratory diseases SARS-CoV-1 SARS-CoV-2 SARS-CoV-2 entry SARS-COV-2 infection Seven Significance the RBD therapeutic response treat variant viral entry viral escape Viral resistance viral spike protein virus wild-type yeast yeast display
[DOI] 10.1073/pnas.2016093117 PMC 바로가기 [Article Type] Biological Sciences

COVID-19 Vaccines Currently under Preclinical and Clinical Studies, and Associated Antiviral Immune Response

Review

Published on 2020-11-032022-10-28
Journal: Vaccines [Category] COVID-19,

Low serum neutralizing anti-SARS-CoV-2 S antibody levels in mildly affected COVID-19 convalescent patients revealed by two different detection methods

경미한 영향을 받은 COVID-19 회복기 환자의 낮은 혈청 중화 항-SARS-CoV-2 S 항체 수준이 두 가지 다른 검출 방법으로 밝혀짐

Article

Published on 2020-11-022022-09-11
Journal: Cellular and Molecular Immunology [Category] Fulltext, MERS, 진단, 치료기술, 치료제,

[키워드] ACE2 acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 affected age angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme 2 Anti-SARS-CoV-2 S anti-SARS-CoV-2 S1 IgG antibodies antibody binding biosafety Cell clinical symptom Clinical symptoms convalescent patient Convalescent patients coronavirus coronavirus disease Coronavirus disease 2019 correlated correlated strongly COVID-19 COVID-19 convalescent patient COVID-19 convalescent patients Donor ELISA enzyme faster IgA antibodies Infection interfere less Neutralization assay neutralization test Neutralizing Neutralizing antibodies neutralizing antibody passive antibody therapy Patient patient age plasma Predictive markers Prevalence RBD Receptor-binding domain respiratory S protein S1 IgG SARS-CoV-2 SARS-CoV-2 S SARS-CoV-2 spike sera serum serum antibodies serum antibody severe acute respiratory syndrome Coronavirus severity stomatitis surrogate virus neutralization test sVNT the receptor-binding domain the SARS-CoV-2 vesicular stomatitis vesicular stomatitis virus viral infection virus neutralization test VSV
[DOI] 10.1038/s41423-020-00573-9 PMC 바로가기 [Article Type] Article

Rabies virus-based COVID-19 vaccine CORAVAX™ induces high levels of neutralizing antibodies against SARS-CoV-2

Article

Published on 2020-10-162022-10-30
Journal: NPJ Vaccines [Category] COVID-19,