Low tricuspid annular plane systolic excursion is associated with a poor outcome in patients with COVID-19 A systematic review and meta-analysis낮은 삼첨판 환형 평면 수축기 여행은 COVID-19 환자의 나쁜 결과와 관련이 있습니다. 체계적인 검토 및 메타 분석Meta-Analysis Published on 2022-02-252022-09-10 Journal: Medicine [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, [키워드] 1.26 95% confidence interval affected age cardiac injury Comorbidities coronavirus coronavirus disease coronavirus disease 19 COVID-19 COVID-19 disease Critically ill Critically ill patient critically ill patients diabete diabetes disease severity echocardiography effect size Egger test greater heterogeneity hypertension incidence indicated Injury mean difference Meta-analysis meta-regression modulated no statistically significant difference nonsurvivor nonsurvivors outcome outcomes Patient patients with COVID-19 prognostic publication bias reduced Registered Sex significantly skewed SMD standardized mean difference statistically significant difference subgroup analysis survivor sustained systematic review TAPSE tricuspid tricuspid annular plane systolic excursion utility ventricular dysfunction was performed were used [DOI] 10.1097/MD.0000000000028971 PMC 바로가기 [Article Type] Meta-Analysis
Duodenal tropism of SARS-CoV-2 and clinical findings in critically ill COVID-19 patientsOriginal Paper Published on 2022-02-182022-10-29 Journal: Infection [Category] COVID-19, COVID19(2023년), MERS, SARS, 치료기술, [키워드] ACE2 applied biopsies bleeding cause caused Characteristics clinical Clinical finding Complication consequence COVID-19 COVID-19 patient Critically ill Critically ill patient critically ill patients detect develop diagnosed direct infection duodenal enterocyte Duodenitis histopathological immunohistochemical staining immunohistochemistry In situ hybridization indication intestinal macroscopic mucosal Patient patients positive Protein Replication Result SARS-CoV-2 SARS-CoV-2 pneumonia SARS-CoV-2 spike protein supplementary material tropism of SARS-CoV-2 viral replication was performed [DOI] 10.1007/s15010-022-01769-z PMC 바로가기 [Article Type] Original Paper
Chronic Critical Illness in Patients with COVID-19: Characteristics and Outcome of Prolonged Intensive Care TherapyArticle Published on 2022-02-172022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] 95% CI Admission ARDS BMI both groups caused CCI center chronic chronic critically ill Coronavirus disease 2019 COVID-19 Critical Critical care Critically ill patient defined Department Factor Germany healthcare ICU illness Invasive mechanical ventilation long-term survival median Medicine Mortality outcome Patient persistent critical illness Prolonged prolonged ICU stay regression analysis required resource Respiratory failure Retrospective study SARS-CoV-2 Sex significantly SOFA score Spread study cohort study period therapy treated university with COVID-19 [DOI] 10.3390/jcm11041049 PMC 바로가기 [Article Type] Article
Effect of Vitamin C on Clinical Outcomes of Critically Ill Patients With COVID-19: An Observational Study and Subsequent Meta-AnalysisMedicine Published on 2022-02-112022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] 95% CI 95% confidence interval acute respiratory distress syndrome Acute respiratory failure Administered administration all-cause mortality anticipated baseline characteristics benefit calculated clinical Clinical outcome Cohort comparable conducted control group coronavirus coronavirus disease COVID-19 Critically ill patient critically ill patients Effect Evidence FIVE ICU Ill intensive care intensive care unit Invasive mechanical ventilation laboratory-confirmed mechanical ventilation Meta-analysis morbidity Mortality pandemic Patient patients Pneumonia Primary outcome provide random effect Randomized controlled trial Randomized controlled trials receiving Registered Registration reported Result review risk searched Standard-of-care subsequent Treatment two groups Vitamin Vitamin C with COVID-19 [DOI] 10.3389/fmed.2022.814587 PMC 바로가기 [Article Type] Medicine
Association of ventilator type with hospital mortality in critically ill patients with SARS-CoV2 infection: a prospective studyResearch Published on 2022-02-082022-10-28 Journal: Annals of Intensive Care [Category] COVID-19, [키워드] 95% CI acute respiratory distress Analysis ARDS association Characteristics COVID-19 Critically ill patient defined died evaluate Factor France hospital hospital discharge ICU identify immunodeficiency in-hospital mortality intensive care Intubated Invasive mechanical ventilation Kaplan–Meier survival curve less management median age men Mortality non-ICU outcome outcomes Patient patient group prospective observational study Prospective Study Result SARS-CoV2 SARS-CoV2 infection serum single-center Study design supplementary material syndrome Transport ventilated patient ventilator was performed was used [DOI] 10.1186/s13613-022-00981-2 PMC 바로가기 [Article Type] Research
Role of Urinary Kidney Stress Biomarkers for Early Recognition of Subclinical Acute Kidney Injury in Critically Ill COVID-19 Patients중환자 COVID-19 환자에서 무증상 급성 신장 손상의 조기 인식을 위한 요로 신장 스트레스 바이오마커의 역할Article Published on 2022-02-082022-09-11 Journal: Biomolecules [Category] 바이오마커, [키워드] 95% CI acute kidney Acute kidney injury Admission AKI binding Biomarker Biomarkers clinical information clinical trials collected Combination Comorbidities concentrations contribute COVID-19 COVID-19 patient COVID-19 patients critical care area Critically ill critically ill COVID-19 patients Critically ill patient critically ill patients develop Early detection Gender growth factor Hospitalization IGFBP7 Ill individual information insulin insulin like growth factor binding protein 7 kidney laboratory data longitudinal cohort study male Mortality neutrophil Neutrophil gelatinase-associated lipocalin on admission persistent proportion Protein Recognition risk factor Risk factors role significantly higher Stress study outcome study outcomes Subclinical Tissue Inhibitor tissue inhibitor of metalloproteinases-2 urinary urinary kidney stress biomarkers. were recorded with COVID-19 [DOI] 10.3390/biom12020275 PMC 바로가기 [Article Type] Article
Emergent Virus Reactivation in SARS-CoV-2-Negative Community Acquired Pneumonia Patients During the COVID-19 PandemicMicrobiology Published on 2022-02-072022-10-31 Journal: Frontiers in Microbiology [Category] COVID-19, [키워드] absence Acquired albumin antibiotic CD4 cellular immune function Chest CT China Clinical characteristics clinical manifestation Clinical outcome CMV Community community acquired pneumonia condition COVID-19 COVID-19 pandemic Critically ill patient dry cough EBV feature Fever ground-glass opacity hemoglobin Herpesviridae HSV-1 immunosuppressed patients initial Lymphocyte count manifestation medical record monotherapy pandemic Patient patients Pneumonia positive positive patient positive rate presenting symptom Prognosis Reactivation regimen T lymphocyte therapeutic option Treatment two group university hospital upper lobe virus viruses [DOI] 10.3389/fmicb.2022.758073 PMC 바로가기 [Article Type] Microbiology
Reactivation of Herpes Simplex Virus Type 1 (HSV-1) Detected on Bronchoalveolar Lavage Fluid (BALF) Samples in Critically Ill COVID-19 Patients Undergoing Invasive Mechanical Ventilation: Preliminary Results from Two Italian CentersBrief Report Published on 2022-02-042022-10-29 Journal: Microorganisms [Category] COVID-19, [키워드] antiviral therapy Antiviral treatment association BALF bronchoalveolar center coronavirus disease COVID-19 COVID-19 patient criteria Critically ill patient cumulative risk described Herpe herpes simplex herpes simplex virus HSV-1 Ill independent predictor intensive care intravenous intubated patient Italian lavage Mechanical Mortality Patient Pneumonia predictor prognostic Reactivation Respiratory function Result retrospective Sample SARS-CoV-2 study inclusion Type Ventilated virus with COVID-19 worsening [DOI] 10.3390/microorganisms10020362 PMC 바로가기 [Article Type] Brief Report
ICU-Associated Costs during the Fourth Wave of the COVID-19 Pandemic in a Tertiary Hospital in a Low-Vaccinated Eastern European CountryArticle Published on 2022-02-042022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, COVID19(2023년), MERS, SARS, [키워드] Antiviral calculated COVID-19 COVID-19 pandemic Critically ill patient demographic duration of hospitalization dysfunction European Healthcare system healthcare-associated costs hospital ICU identify immunomodulatory therapy increase in intensive care intensive care unit lung involvement management measure medication medication costs non-COVID-19 patient organ dysfunction pandemic Patient patients renal replacement therapy retrospective cohort risk factor Romania SARS-COV-2 infection severity Support Tertiary Treatment Wave were recorded [DOI] 10.3390/ijerph19031781 PMC 바로가기 [Article Type] Article
Complement Activation via the Lectin and Alternative Pathway in Patients With Severe COVID-19중증 COVID-19 환자의 렉틴 및 대체 경로를 통한 보완 활성화Immunology Published on 2022-02-022022-09-11 Journal: Frontiers in Immunology [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, [키워드] activate activated Activation Acute kidney injury acute respiratory syndrome addition Alternative pathway alveolar alveolar septa analyzed Autopsy both groups both lungs C1q C3c C5b-9 causes cerebral hemorrhage CFD characterized collateral tissue complement Complement activation complement deposition Control correlated correlation COVID-19 COVID-19 patient COVID-19 patients Critically ill Critically ill patient critically ill patients Cytokines Defense deposit deposition deregulated died edema Factor followed by hyaline membrane hyaline membranes Immune cell immune cells immune system immunohistochemistry in both groups indicated Inflammatory response Injury investigated involved kidney kidneys lectin lectin pathway Local lung Lung injury Lungs MASP-2 membranes Mortality MPO myeloperoxidase neutrophil Neutrophils occurred Pathogens Patient patients with COVID-19 peritubular capillaries peritubular capillary positive Prevent pro-inflammatory cytokines Pulmonary embolism respiratory SARS-COV-2 infection SARS-CoV-2 spike protein SARS-CoV-2 virus SARS-CoV-2 virus particle SARS-CoV-2 virus particles semi-quantitative Severe acute respiratory syndrome severe COVID-19 SIGN significantly significantly higher significantly more Spike protein subsequent thrombi tissue damage tissue injury Treatment with COVID-19 worsening [DOI] 10.3389/fimmu.2022.835156 PMC 바로가기 [Article Type] Immunology