Clinical, Serological, and Histopathological Similarities Between Severe COVID-19 and Acute Exacerbation of Connective Tissue Disease-Associated Interstitial Lung Disease (CTD-ILD)Immunology Published on 2020-10-022022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, MERS, SARS, [키워드] Activation acute exacerbation acute respiratory distress Analysis ARDS autoantibodies autoantibody Autoimmune Autoimmunity clinical Clinical course collagen Computed tomography connective tissue connective tissue disease coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient COVID-19 patients detection determine died disease ENA enrolled exacerbating Exacerbation feature fibroblast FIVE heterogeneous High-resolution histopathological finding Histopathology immunoblot immunofluorescence intensive care treatment Interstitial lung disease interstitial thickening investigated Laboratory testing mechanism objective Occurrence overlapping pathophysiology Patient Pneumonia positive predict Respiratory failure Result SARS-CoV-2 SARS-COV-2 infection serological severe complication severe COVID-19 significantly similarity syndrome the disease Therapeutic strategies tissue sample understanding was performed [DOI] 10.3389/fimmu.2020.587517 PMC 바로가기 [Article Type] Immunology
COVID-19: An Emerging Threat to Antibiotic Stewardship in the Emergency DepartmentEndemic Infections Published on 2020-09-072022-10-28 Journal: Western Journal of Emergency Medicine [Category] COVID-19, MERS, [키워드] antibiotic approach Biomarker Care Combination COVID-19 COVID-19 patient demonstrated Department diagnostics Effect effective Efficacy effort Emergency exacerbating host response implementation Intervention lack mitigate pandemic Pathways Patient patient safety public health representing Research threat viral pathogens while [DOI] 10.5811/westjem.2020.7.48848 PMC 바로가기 [Article Type] Endemic Infections
An urgent impetus for action: safe inhalation interventions to reduce COVID-19 transmission and fatality risk among people who smoke crack cocaine in the United KingdomResearch article Published on 2020-09-012022-10-05 Journal: The International Journal on Drug Policy [Category] SARS, 신약개발, [키워드] inhalation equipment pipe sharing respiratory risk administration benefit chronic obstructive COPD COVID 19 COVID-19 COVID-19 transmission Crack crack cocaine drug drugs equipment Evidence exacerbating fatality Health Intervention London measure people who use drugs Prevalence Protective pulmonary disease Qualitative reduce reduction review rising risk Safe scaled up smoking survey Transmission United Kingdom [DOI] 10.1016/j.drugpo.2020.102829 [Article Type] Research article
Pandemic Surveillance and Racialized Subpopulations: Mitigating Vulnerabilities in COVID-19 AppsSymposium: COVID-19 Published on 2020-08-252022-10-29 Journal: Journal of bioethical inquiry [Category] Coronavirus, MERS, SARS, [키워드] benefit COVID-19 COVID-19 pandemic debate demonstrated Digital health technologies Disease surveillance effective response Efficacy employment equity exacerbating form groups implementation Justice Measures pandemic Pandemic disease surveillance Racial inequality Racialized subpopulations risk Solidarity COVID-19 apps subpopulation subpopulations Surveillance the disease vulnerability [DOI] 10.1007/s11673-020-10034-7 PMC 바로가기 [Article Type] Symposium: COVID-19
COVID-19 and possible links with Parkinson’s disease and parkinsonism: from bench to bedsidePerspective Published on 2020-08-202022-10-04 Journal: NPJ Parkinson's Disease [Category] 치료제, [키워드] 1918 influenza ACE2 ACE2 expression activated angiotensin-converting enzyme 2 appear Astrocyte Basic science Brain Case report cell type Central nervous system Clinical treatment Consensus coronavirus disease COVID-19 Encephalopathy Evidence exacerbating Express expression flu healthy Hyposmia include Infection Inflammation Major microglia MONITOR neuronal neurons pandemic Parkinson’s disease Parkinsonism patients with COVID-19 Perspective receptor reported SARS-CoV-2 subject Symptom Translational research unlikely Vascular viral entry virus while [DOI] 10.1038/s41531-020-00123-0 PMC 바로가기 [Article Type] Perspective
Neurological Manifestations of Severe SARS-CoV-2 Infection: Potential Mechanisms and Implications of Individualized Mechanical Ventilation SettingsNeurology Published on 2020-08-122022-11-01 Journal: Frontiers in Neurology [Category] COVID-19, [키워드] 2019-nCoV addition affected Brain caused change complex interaction coronavirus Coronavirus disease 2019 COVID-19 Critically ill patient distress dry cough endothelial cell damage exacerbating fatigue Fever Hyperinflammatory Impact impairment include Inflammatory response interactions lung manifestation Mechanical mechanical ventilation nervous system neurological neurological manifestation neurological manifestations neurotropism Novel coronavirus outbreak outcomes pandemic pathogenic mechanism physiological Potential reported Respiratory Support SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 pneumonia setting Spread Stress Typical ventilatory strategy Wuhan, China [DOI] 10.3389/fneur.2020.00845 PMC 바로가기 [Article Type] Neurology
Cardiovascular involvement during COVID-19 and clinical implications in elderly patients. A reviewReview Article Published on 2020-08-052022-10-04 Journal: Annals of Medicine and Surgery [Category] 신약개발, [키워드] ACE2 Activation acute coronary syndromes Analysis Betacoronavirus cardiac arrhythmias cardiometabolic cardiovascular cardiovascular drugs cardiovascular system clinical implication common Comorbidities Comorbidity contribute Corona COVID-19 Cytokine release syndrome Cytokine storm death elderly patients event Evidence exacerbating frailty Frequency heart failure implication individuals Inflammation management molecular multi-organ failure myocarditis Older pathogenic pathogenic mechanism pro-inflammatory state Repurposed drug responsible SARS-CoV 2 SARS-CoV-2 SARS-COV-2 infection severity of COVID-19 Severity of disease targets thrombosis Treatment troponin turn Vascular Vasculitis [DOI] 10.1016/j.amsu.2020.07.054 PMC 바로가기 [Article Type] Review Article
Immunophenotyping of COVID-19 and influenza highlights the role of type I interferons in development of severe COVID-19COVID-19 및 인플루엔자의 면역표현형은 중증 COVID-19 발병에서 I형 인터페론의 역할을 강조합니다Research Articles Published on 2020-07-102022-09-14 Journal: Science Immunology [Category] Fulltext, SARS, 유전자 메커니즘, 진단, [키워드] accompanied acute respiratory distress blood immune cell Cell classical monocyte coronavirus disease COVID-19 driving exacerbating exhibited Factor feature healthy donors highlight hyper-inflammation identify Immunophenotyping Inflammation Inflammatory Inflammatory response Influenza Mild mononuclear cell Patient PBMCs performed Peripheral blood progression reveal RNA sequencing SARS-CoV-2-infected individual severe COVID-19 single-cell RNA-seq syndrome systemic inflammation type I Type I IFN type I interferon with COVID-19 [DOI] 10.1126/sciimmunol.abd1554 PMC 바로가기 [Article Type] Research Articles
Adaptation to SARS‐CoV‐2 under stress: Role of distorted informationOriginal Paper Published on 2020-06-132022-10-31 Journal: European Journal of Clinical Investigation [Category] COVID-19, [키워드] adaptation Analysis Care caused content country Coverage COVID‐19 COVID‐19 patients COVID‐19 disease epidemiological exacerbating exaggerated information Facebook FIVE healthcare Healthcare system healthcare system stress Healthcare systems hospital information Instagram many cases material media misallocation of resources negative influence Nurse pandemic Panic population adaptation problem problems recommendation resources Result role SARS‐CoV‐2 social panic Spread Stress Surveying turn virus [DOI] 10.1111/eci.13294 PMC 바로가기 [Article Type] Original Paper
Projecting hospital utilization during the COVID-19 outbreaks in the United States530 Published on 2020-04-212022-10-29 Journal: Proceedings of the National Academy of Sciences of [Category] COVID-19, SARS, [키워드] absence alleviate analyses basic reproduction number case fatality rates Case isolation Community coronavirus disease COVID-19 COVID-19 outbreak Critical care critical care need Critically ill demographics effort estimate exacerbating expand facilitate Government Healthcare system highlight hospital Hospitalization hygiene ICU ICUs individual infected cases intensive care unit interquartile range outbreak Patient Policy proportion public health reducing required resource SARS–CoV-2 Self-isolation sick Significance symptom onset symptomatic individual the epidemic the timing the United State The United States trajectory Transmission treat Treatment Vaccine ventilator [DOI] 10.1073/pnas.2004064117 PMC 바로가기 [Article Type] 530