healthy individual – Page 10 – Communicable Diseases Research

Sustained expression of inflammatory monocytes and activated T cells in COVID‐19 patients and recovered convalescent plasma donors

Original Article

Published on 2021-08-062022-10-30
Journal: Immunity, Inflammation and Disease [Category] COVID-19, MERS, SARS,

Immune cell residency in the nasal mucosa may partially explain respiratory disease severity across the age range

비강 점막의 면역 세포 거주는 연령대의 호흡기 질환 심각성을 부분적으로 설명 할 수 있습니다.

Article

Published on 2021-08-052022-09-10
Journal: Scientific Reports [Category] MERS, SARS, 유전자 메커니즘,

[키워드] Adults age analyzed antiviral properties applied Cell cell type cellular changes in children correlated COVID-19 severity epigenome epithelial cell epithelial cells Evidence explain Functional genomics generate healthy individual healthy individuals immune immune activation Immune cell immune cell type immunization strategies individual infection with SARS-CoV-2 innate immune response innate immune system Mucosal immunology nasal nasal mucosa Previous studies previous study proportion reflect resource respiratory Respiratory disease respiratory infection robust SARS-CoV-2 Sequencing severity Single-cell RNA-sequencing suggested T cell transcriptional underlie uninfected
[DOI] 10.1038/s41598-021-95532-3 PMC 바로가기 [Article Type] Article

Von Willebrand factor and ADAMTS13 activity as clinical severity markers in patients with COVID-19

COVID-19 환자의 임상 중증도 마커로서의 폰 빌레브란트 인자 및 ADAMTS13 활성

Article

Published on 2021-08-012022-09-11
Journal: Journal of Thrombosis and Thrombolysis [Category] MERS, SARS, 바이오마커,

[키워드] ADAMTS13 age and gender Antigen clinical outcomes Clinical severity coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 outpatient COVID-19 outpatients COVID-19 patient COVID-19 patients D-dimer diagnosed disease severity Endothelial dysfunction endothelial injury enrolled evaluate fibrinogen healthy individual highest hypercoagulability ICU patient ICU Patients Imbalance increase increase in Inpatient Inpatients intensive care intensive care unit lead lowest marker mechanism Medical conditions Non-COVID-19 Patient patients with COVID-19 plasma predict Prospective Study prothrombotic state recruited reduction reduction in thrombotic thrombotic risk von Willebrand factor vWF were measured with COVID-19
[DOI] 10.1007/s11239-021-02457-9 PMC 바로가기 [Article Type] Article

Altered oral and gut microbiota and its association with SARS-CoV-2 viral load in COVID-19 patients during hospitalization

입원 중 COVID-19 환자에서 변경된 구강 및 장내 미생물 및 SARS-CoV-2 바이러스 부하와의 연관성

Article

Published on 2021-07-222022-09-12
Journal: NPJ Biofilms and Microbiomes [Category] SARS, 바이오마커, 유전자 메커니즘, 진단,

[키워드] 16S rRNA Alpha alteration Altered association Bacterial baseline Biomarkers calculated clearance clearance of SARS-CoV-2 clinical microbiology collected Community COVID-19 COVID-19 patient COVID-19 patients digestive tract dimension disease elevated examined Fecal sample fecal samples Gut gut microbiota healthy individual healthy individuals Hospitalization identify Immune homeostasis indicated intestinal flora investigated maintenance microbe microbes microbial Microbiome pathophysiology Patient rRNA SARS-COV-2 infection SARS-CoV-2 viral load Sequencing severity Sex susceptibility throat swab Treatment strategies treatment strategy Viral load vital role vital roles
[DOI] 10.1038/s41522-021-00232-5 PMC 바로가기 [Article Type] Article

Theoretical investigation of pre-symptomatic SARS-CoV-2 person-to-person transmission in households

Article

Published on 2021-07-142022-10-29
Journal: Scientific Reports [Category] COVID-19, SARS,

Presence and strength of binding of IgM, IgG and IgA antibodies against SARS-CoV-2 during CoViD-19 infection

CoViD-19 감염 중 SARS-CoV-2에 대한 IgM, IgG 및 IgA 항체의 존재 및 결합 강도

Article

Published on 2021-07-012022-09-12
Journal: Biosensors & bioelectronics [Category] SARS, 진단,

High throughput surface plasmon resonance imaging method for clinical detection of presence and strength of binding of IgM, IgG and IgA antibodies against SARS-CoV-2 during CoViD-19 infection

Method Article

Published on 2021-06-292022-10-04
Journal: MethodsX [Category] 치료기술,

Multiplexed and High-Throughput Label-Free Detection of RNA/Spike Protein/IgG/IgM Biomarkers of SARS-CoV-2 Infection Utilizing Nanoplasmonic Biosensors

나노플라즈몬 바이오센서를 활용한 SARS-CoV-2 감염의 RNA/스파이크 단백질/IgG/IgM 바이오마커의 다중 및 고처리량 무표지 검출

Article

Published on 2021-06-292022-09-11
Journal: Analytical Chemistry [Category] MERS, SARS, 진단, 치료기술,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 antibodies antibody applied approach Biomarker biosensor calculated caused Characteristics clinician coronavirus COVID-19 COVID-19 outbreak COVID-19 pandemic detect detection diagnostic diagnostic test diagnostic tests diagnostics disease effective Genes healthy individual healthy individuals IgG and IgM IgM antibodies Infection limit of detection Mann-Whitney nonparametric MOST multiplex Negative predictive value nonparametric test P -value Patient plasma sample plasma samples platform Positive predictive value positive rate Predictive value Prevalence progression proof proof of concept provide receiving respiratory responses SARS-CoV-2 screening test sensitivity severe acute respiratory syndrome Coronavirus severity specificity Spike protein Stage subunits Treatment true negative true positive rate unmet need Viral viral nucleic acid virus
[DOI] 10.1021/acs.analchem.0c05300 PMC 바로가기 [Article Type] Article

Potent SARS-CoV-2-Specific T Cell Immunity and Low Anaphylatoxin Levels Correlate With Mild Disease Progression in COVID-19 Patients

강력한 SARS-CoV-2-특이적 T 세포 면역 및 낮은 아나필라톡신 수치는 COVID-19 환자의 경증 질병 진행과 상관관계가 있습니다

Immunology

Published on 2021-06-142022-09-11
Journal: Frontiers in Immunology [Category] MERS, SARS, 진단, 치료법,

[키워드] addition analyzed anaphylatoxin anaphylatoxin C3a Antibody titer Antibody titers Blood C5a caused CD4 CD8 cellular characterized clearance Complete coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient Critical critical COVID-19 patient disease severity elevated ELISA ELISPOT ELISpot assay evaluated flow cytometry healthy individual highest humoral immune response IFNγ IgG immune complex immune responses immunodominant indicate infected individuals Level Lymphocytes lymphopenia Mild mild infections mononuclear cell mononuclear cells Mortality neutralization ability neutralizing Abs Neutralizing activity nucleocapsid Patient patients peptide peptide pool peripheral Peripheral blood Peripheral blood mononuclear cells potent reduced respiratory Respiratory system robust SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV-2-infected individuals SARS-CoV-2-specific antibodies SARS-CoV-2-specific antibody severe disease progression significantly specific antibodies Spike proteins T cell T cell immunity T cell response T cell responses T cells T lymphocyte Viral viral infection viral infections
[DOI] 10.3389/fimmu.2021.684014 PMC 바로가기 [Article Type] Immunology

Evaluation of mental health and anxiety level among hepatitis C patients during COVID-19 pandemic in Pakistan

Original Research Article

Published on 2021-06-122022-10-31
Journal: Egyptian Liver Journal [Category] COVID-19,

[키워드] age Anxiety BAI Beck calculated Chinese conditions conducted COVID-19 COVID-19 pandemic demographic factor female Gender HCV healthy individual Hepatitis hepatitis C highest Infection Infectious disease inventory male males measure Mental mental health MOST Pakistan pandemic Patient patients Protective Psychological recorded respondent Result significant difference significantly higher Stress was recorded was used
[DOI] 10.1186/s43066-021-00120-9 PMC 바로가기 [Article Type] Original Research Article