hospitalised patient – Page 10 – Communicable Diseases Research

COVID-19 admission risk tools should include multiethnic age structures, multimorbidity and deprivation metrics for air pollution, household overcrowding, housing quality and adult skills

Respiratory Infection

Published on 2021-08-092022-10-28
Journal: BMJ Open Respiratory Research [Category] COVID-19, MERS, SARS,

Age-Adjusted Associations Between Comorbidity and Outcomes of COVID-19: A Review of the Evidence From the Early Stages of the Pandemic

Public Health

Published on 2021-08-062022-10-31
Journal: Frontiers in Public Health [Category] COVID-19, MERS, SARS,

Remdesivir for the treatment of COVID-19

코로나19 치료제 렘데시비르

Article

Published on 2021-08-052022-09-11
Journal: The Cochrane database of systematic reviews [Category] SARS, 임상, 치료제,

[키워드] 95% CI 95% confidence interval adverse event adverse events age all-cause mortality antiviral medicine approach authorisation baseline CENTRAL certainty certainty of evidence chance citation clinical Clinical improvement Clinical outcome clinical outcomes clinical status Cochrane COVID-19 Study Register comparable conducted contribute Controlled controlled trials coronavirus disease coronavirus diseases COVID-19 COVID-19 patient COVID-19 patients COVID-19 research Data collection decrease defined diagnosed died disease severity Effect Efficacy and safety Emergency use Ethnicity evaluated Evidence excluded FIVE Future Gender high risk High-flow oxygen hospitalised hospitalised patient Hospitalised patients identify increase index individual information inhibit initial Invasive mechanical ventilation lack liberation life low-flow oxygen maintain Mask mechanical ventilation media medRxiv methodology Missing data missing value missing values Mortality MOST nasal prong nasal prongs need for oxygen no difference no effect Non-invasive non-invasive mechanical ventilation non-invasive ventilation observation outcome outcomes oxygen participant Participants Patient Placebo potential benefit potential benefits Quality of life randomised randomised controlled trial Randomised controlled trials RCT RCTs receive recruit registry Remdesivir reported required Respiratory Support risk risk difference risk of bia risk ratio RoB 2 SARS-CoV-2 SARS-COV-2 infection Science Citation Index searched Selection Serious Adverse Event Serious Adverse Events severity Source standard care subgroup subgroups supplemental oxygen systematic review Treatment viral replication Web of Science WHO WHO International Clinical Trials Registry Platform worsening
[DOI] 10.1002/14651858.CD014962 PMC 바로가기 [Article Type] Article

SARS-CoV-2 nosocomial infection acquired in a French university hospital during the 1st wave of the Covid-19 pandemic, a prospective study

Observational Study

Published on 2021-08-052022-10-04
Journal: Antimicrobial Resistance and Infection Control [Category] MERS, SARS, 임상,

[키워드] acquisition approval Cluster Compliance conducted COVID-19 death defined determine Diagnosis died effective evaluated first symptoms First wave France French hand hygiene HCW HCWs healthcare healthcare worker Healthcare-associated infection hospital hospitalisation hospitalised patient hygiene interquartile IRB lockdown mandatory Mask measure Measures monitoring nosocomial nosocomial COVID-19 Nosocomial infection outbreak pandemic Patient positive prospective observational study Prospective Study reduced respiratory virus Result risk factor SARS-CoV-2 severe COVID-19 symptom onset tested Transmission university university hospital virus was obtained
[DOI] 10.1186/s13756-021-00984-x PMC 바로가기 [Article Type] Observational Study

Green tea intake and its effect on laboratory parameters and disease symptoms in hospitalised patients with Covid 19: a structured protocol for a randomized controlled trial

Covid 19 입원 환자의 실험실 매개변수 및 질병 증상에 대한 녹차 섭취 및 영향: 무작위 대조 시험을 위한 구조화된 프로토콜

Letter

Published on 2021-08-032022-09-10
Journal: Trials [Category] MERS, SARS, 임상,

[키워드] 1:1 age All participants anticipated appearance assigned Blinding block block size block sizes blood count C-reactive protein Capsule categories CBC Chain Reaction change city clinical trial Coagulation Coagulopathy color company complete blood count computer-generated conducted control group COVID-19 COVID-19 diagnosis COVID-19 infection CRP CRP level CRP levels dinner disease symptom disease symptoms Disseminated intravascular coagulation dissemination division divisions double-blinded element erythrocyte sedimentation erythrocyte sedimentation rate ESR exploratory study green tea green tea supplement hospitalised patient inclusion criteria Infection Intervention intervention group intravascular coagulation Iran kidney Kidney failure laboratory parameter Laboratory parameters lactation Mild-to-moderate number objective outcome participant Patient patients with COVID-19 performed Placebo polymerase chain polymerase chain reaction Pregnancy protocol random randomised randomised controlled trial randomization Randomized controlled trial Randomly RCT real-time polymerase chain reaction recruit Registered required researcher RT-PCR Sample size sedimentation rate Sex shape status supplementary material total sample size Treatment treatment for COVID-19 twice a day Version was determined website
[DOI] 10.1186/s13063-021-05462-8 PMC 바로가기 [Article Type] Letter

COVID-19, corticosteroids and public health: a reappraisal

COVID-19, 코르티코스테로이드 및 공중 보건: 재평가

Meta-Analysis

Published on 2021-08-012022-09-11
Journal: Public health [Category] SARS, 변종, 신약개발,

A novel strategy for SARS-CoV-2 mass screening with quantitative antigen testing of saliva: a diagnostic accuracy study

타액의 정량적 항원 검사를 통한 SARS-CoV-2 대량 스크리닝을 위한 새로운 전략: 진단 정확도 연구

Article

Published on 2021-08-012022-09-11
Journal: The Lancet. Microbe [Category] SARS, 치료기술,

[키워드] Accuracy Antigen Asymptomatic clinically close contact Community community health Concentration concentrations Concordance COVID-19 credible interval CrI Cutoff cutoff value detect develop diagnostic Diagnostic accuracy enrolled enzyme enzyme immunoassay followed by Fujirebio Health hospitalised patient Hospitalised patients immunoassay IMPROVE initial International Japan Japanese less Local mass Mass screening Ministry of Health Nasopharyngeal swab negativity NPs participant positive Prevalence Probability proportion proportions provide quantified Quantitative Quantitative RT-PCR Result RT-PCR RT-qPCR Saliva saliva samples salivary SARS-CoV-2 SARS-CoV-2 detection SARS-CoV-2 nucleoprotein screening strategy sensitivity specificity Test tested threshold Tokyo utility was obtained Welfare
[DOI] 10.1016/S2666-5247(21)00092-6 PMC 바로가기 [Article Type] Article

Janus Kinase Inhibitors and Coronavirus Disease (COVID)-19: Rationale, Clinical Evidence and Safety Issues

Review

Published on 2021-07-282022-10-28
Journal: Pharmaceuticals [Category] COVID-19,

[키워드] access administration adverse effects age Anti-inflammatory anti-viral effects Antiviral approach approved authorization Baricitinib candidate drug clinical clinical evidence Clinical practice clinical trial Combination Complication Coronavirus Disease (COVID)-19 COVID-19 Cytokine storm drug drug interaction Effectiveness Emergency European Medicines Agency expected extracorporeal membrane oxygenation feature food hospitalised patient hospitalized patient immune Inconclusive infections inhibitors Invasive mechanical ventilation issue Jak JAK inhibitor janus janus kinase (JAK) inhibitors kinase Liver injury multifunctional myelofibrosis novel coronavirus disease offered Open-label patients with COVID-19 pharmacokinetic pharmacological plan rationale real word evidence Remdesivir rheumatoid arthritis ruxolitinib Safety supplemental oxygen therapy thrombosis treat Treatment Viral load
[DOI] 10.3390/ph14080738 PMC 바로가기 [Article Type] Review

A randomized open-label trial to evaluate the efficacy and safety of triple therapy with aspirin, atorvastatin, and nicorandil in hospitalised patients with SARS Cov-2 infection: A structured summary of a study protocol for a randomized controlled trial

SARS Cov-2 감염으로 입원한 환자에서 아스피린, 아토르바스타틴, 니코란딜을 사용한 삼중 요법의 효능과 안전성을 평가하기 위한 무작위 공개 시험: 무작위 대조 시험을 위한 연구 프로토콜의 구조화된 요약

Letter

Published on 2021-07-152022-09-10
Journal: Trials [Category] SARS, 임상,

[키워드] 1:1 ACHE Acute coronary syndrome Acute kidney injury acute renal failure adequate hydration adjuvant therapy Admission allergy ALT/AST Altered mental status Anti-inflammatory anticoagulation antipyretics Antithrombotic approved ARDS Aspirin AST/ALT atorvastatin bleeding Blinding block randomization Breastfeeding brown urine change characterized clinical clinical feature Clinical features Coagulopathy college Combination comorbid condition comorbid conditions comparator conducted control group coronary syndrome Corticosteroid Corticosteroids cough COVID-19 CPK creatine creatine kinase creatinine CRP current therapy Dexamethasone dissemination dose drug dysfunction Dyspnoea dysregulation effective Efficacy and safety element Endothelial dysfunction enrolled ethical committee evaluate excluded ferritin Fever followed by greater heparin hepatotoxicity Hospital admission hospital discharge Hospital mortality Hospital stay hospitalised patient Hospitalised patients hyperbilirubinemia hypoxia ICMR IEC immune dysregulation immunomodulatory impaired consciousness in-hospital mortality India Inflammation Inflammatory marker inflammatory markers Intervention intervention group intolerance intravenous Intravenous remdesivir invasive limit liver low molecular weight low molecular weight heparin management marker mechanical ventilation medication medications moderate muscle ache myalgia Myoglobin Myopathy myositis national guidelines Nicorandil Non-invasive number objective once daily Open-label open-label trial outcome oxygen Oxygen requirement oxygen support participant pathophysiologic pathophysiology Patient Platelet Platelet count Pneumonia positive Pregnancy Primary outcome progression protocol raised Rajendra Prasad Randomised control trial randomization randomize Randomized Randomized controlled trial randomly divided receive recruitment reducing mortality Registered registry Remdesivir renal failure reported respiratory rate rhabdomyolysis room air RT-PCR safety endpoint safety endpoints Sample size SARS-CoV-2 infected patient SARS-COV-2 infection Schematic screened Secondary outcomes Sepsis serum serum markers severe disease Shock significant interaction SpO2 Standard Standard of care starting dose statin statins Study design Study protocol substrates supplementary material Symptom Symptomatic treatment Tablet therapeutic therapeutic agent therapy thrombocytopenia Treatment Trial Trial registration two-arm parallel ULN Urine weakness website
[DOI] 10.1186/s13063-021-05361-y PMC 바로가기 [Article Type] Letter

Changes in in-hospital mortality in the first wave of COVID-19: a multicentre prospective observational cohort study using the WHO Clinical Characterisation Protocol UK

Observational Study

Published on 2021-07-012022-10-04
Journal: The Lancet. Respiratory Medicine [Category] 임상,

[키워드] 95% CI A significant reduction accounted Admission all age groups all ethnic groups association assumed both sexes change changed changes in clinical Clinical sign Community Comorbidities Comorbidity confounder COVID-19 Critical care declined defined demographics died dose driver eligible England explained Factors finding First wave funding gradually increased group high risk hospital hospitalised patient identify Illness severity in-hospital mortality Infection ISRCTN registry knowledge Mediation analysis Medical Research Council Mortality multicentre natural effects model non-invasive ventilation Odds ratio Older outcome pandemic Patient patients patients with COVID-19 Primary outcome proportion prospective cohort prospective observational cohort recruited reduction reduction in Registered respiratory Respiratory Support risk RT-PCR test severe disease severity steroid treatment symptoms of COVID-19 the WHO use of steroid WHO with COVID-19
[DOI] 10.1016/S2213-2600(21)00175-2 PMC 바로가기 [Article Type] Observational Study