Leveraging community mortality indicators to infer COVID-19 mortality and transmission dynamics in Damascus, SyriaArticle Published on 2021-04-222022-10-29 Journal: Nature Communications [Category] COVID-19, MERS, SARS, [키워드] accounting all-cause mortality Americas Community Computational models country COVID-19 COVID-19 mortality COVID-19 pandemic COVID-19 transmission Damascus death Developing world Epidemiology Europe exceeded health system health systems hospital lower mortality mathematical Middle East Mortality reported SARS-CoV-2 sensitivity Transmission dynamics [DOI] 10.1038/s41467-021-22474-9 PMC 바로가기 [Article Type] Article
Mortality Benefit of Convalescent Plasma in COVID-19: A Systematic Review and Meta-AnalysisMedicine Published on 2021-04-092022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] 95% CI 95% confidence interval adverse event Analysis article benefit Care classical Clinical symptoms clinically concomitant treatment conducted convalescent convalescent plasma COVID-19 COVID-19 patient defined discharge drugs effective Efficacy and safety Evidence exploratory study Future Health heterogeneity highest hospital Intervention lower mortality Meta-analysis Mortality mortality rate nine observational study outcomes Patient patients patients died patients treated plasma plasma therapy Primary outcome quantitative synthesis Randomized controlled trial RCTs receive reduced researcher review SARS-CoV 2 secondary outcome sensitivity analysis significantly lower statistical statistically significant reduction Steroids subgroup analysis supportive care Systemic review systemic review and meta-analysis the timing therapeutic option therapy Treatment [DOI] 10.3389/fmed.2021.624924 PMC 바로가기 [Article Type] Medicine
Physical Activity and the Risk of COVID-19 Infection and Mortality: A Nationwide Population-Based Case-Control StudyArticle Published on 2021-04-062022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] 95% CI 95% confidence interval activity addition association Control control group coronavirus disease COVID-19 COVID-19 infection COVID-19 pandemic database decrease examined highlighting Infection infections insurance Korean lower mortality lower risk moderate morbidity morbidity and mortality Mortality Odds ratio physical activity positive public health questionnaire Randomly reduce Regular Respiratory Coronavirus resulting risk risk of COVID-19 selected service severe acute respiratory coronavirus 2 social distancing South Standard deviation tested the patient [DOI] 10.3390/jcm10071539 PMC 바로가기 [Article Type] Article
Convalescent plasma treatment is associated with lower mortality and better outcomes in high-risk COVID-19 patients – propensity-score matched case-control studyResearch article Published on 2021-04-012022-10-05 Journal: International Journal of Infectious Diseases [Category] SARS, 치료법, [키워드] active cancer administration age cardiac insufficiency case-control study Comorbidities convalescent plasma COVID-19 COVID-19 disease COVID-19 patient COVID-19 patients cumulative death death in COVID-19 Efficacy and safety finding hospital Hospitalization Hospitalized hospitalized patient ICU in both groups incidence intensive care lower mortality lower risk mortality rate mortality rate; no significant difference objective outcome parameter Patient patients treated plasma Primary outcome Prospective Study PSM Result risk of death SARS-CoV-2 secondary outcome significant difference significantly increased significantly lower standard care treated Treatment two group two groups ventilator was selected with COVID-19 [DOI] 10.1016/j.ijid.2021.02.054 [Article Type] Research article
Prior Treatment with Statins is Associated with Improved Outcomes of Patients with COVID-19: Data from the SEMI-COVID-19 RegistryObservational Study Published on 2021-04-012022-10-05 Journal: Drugs [Category] SARS, 임상, [키워드] Acute kidney injury acute respiratory distress addition AKI all-cause mortality analyzed ARDS Clinical characteristics COVID-19 COVID-19 disease cross-sectional decrease develop Hospital admission Hospitalization Hospitalized Improved IMV in-hospital mortality incidence individual Invasive mechanical ventilation less lower mortality maintain network outcome Patient patients with COVID-19 Prevalence Probability Propensity score propensity score matching receiving reduced registry required Retrospective multicenter study risk Sepsis severe COVID-19 Spanish statin syndrome therapy treated Treatment was used with COVID-19 withdrawn [DOI] 10.1007/s40265-021-01498-x PMC 바로가기 [Article Type] Observational Study
Viral genomic, metagenomic and human transcriptomic characterization and prediction of the clinical forms of COVID-19COVID-19의 임상 형태에 대한 바이러스 게놈, 메타게놈 및 인간 전사체 특성화 및 예측Clinical Trial Published on 2021-03-292022-09-10 Journal: PLoS Pathogens [Category] SARS, 유전자 메커니즘, 임상, 치료기술, [키워드] activate activating acute respiratory distress syndrome Acute respiratory failure Analysis antagonists Bacteria candidate Candidates caused Characteristics characterized clinical form collected COVID-19 COVID-19 pneumonia CXCR2 cytokine Diagnosis disease distress ENhance Factor feature female gender form fungi Genetic genomic high mortality rate Host identify IL-8 Immune cell immune cells infiltration Inflammatory response intensive care intensive care unit lower mortality metagenomic Mild Nasopharyngeal swab nasopharyngeal swabs neutrophil neutrophil infiltration outpatients overactive overexpression pandemic parasite parasites pathophysiology pathway Patient patients hospitalized Pneumonia pulmonary disease receptor respiratory respiratory distress Respiratory distress syndrome Respiratory failure respiratory symptom respiratory symptoms resulting SARS-CoV-2 Severe case severe COVID-19 Severe COVID-19 pneumonia severe pneumonia severity severity of COVID-19 shotgun syndrome T helper the disease tissue damage transcript transcriptomic transcriptomics Treatment turn upper respiratory Viral viruses was performed were used [DOI] 10.1371/journal.ppat.1009416 PMC 바로가기 [Article Type] Clinical Trial
Trends of COVID-19 Admissions in an Italian Hub during the Pandemic Peak: Large Retrospective Study Focused on Older SubjectsArticle Published on 2021-03-072022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] 95% CI 95% confidence interval Admission age analyzed association chronic disease Chronic diseases clinical feature Comorbidity Coronavirus disease-19 COVID-19 COVID-19 phenotype Disabled exhibited Factor female gender frailty functional hospital Hospitalized involved IQR Italian laboratory data Logistic regression lower mortality Mortality Multimorbidity Odds ratio Older outbreak outcome outcomes pandemic PaO Patient Pneumonia positive RT-PCR Prognosis Prognostic factors radiological feature respiratory impairment Retrospective study rising RT-PCR SARS-CoV-2 Stratification subject Temporal trends trend variable with COVID-19 [DOI] 10.3390/jcm10051115 PMC 바로가기 [Article Type] Article
Clinical Features and Prognostic Factors of 245 Portuguese Patients Hospitalized With COVID-19Emergency Medicine Published on 2021-03-042022-10-31 Journal: Cureus [Category] COVID-19, [키워드] 30-Day mortality active cancer acute respiratory syndrome affected age approach articles Artificial respiration association Cancer clinical Comorbidities coronavirus country COVID-19 COVID-19 patient death rate described Disease progression Diseases Europe European country explain Factor First wave help high mortality hospital Hospitalization Hospitalized hospitalized patient Hydroxychloroquine identify incidence of COVID-19 increased mortality Infection lower mortality males material median age Mortality occurred outcome outcomes pandemic Patient performed Portugal Previous studies Primary outcome prospective observational study Protective reflect reported Result risk factor SARS-CoV-2 secondary outcome symptomatic the patient treated ventilatory support with COVID-19 [DOI] 10.7759/cureus.13687 PMC 바로가기 [Article Type] Emergency Medicine
Healthcare workers hospitalized due to COVID-19 have no higher risk of death than general population. Data from the Spanish SEMI-COVID-19 RegistryClinical Trial Published on 2021-02-192022-10-04 Journal: PLoS ONE [Category] MERS, 임상, [키워드] 95%CI Admission age Clinical severity cohort study Comorbidity COVID-19 death determine Factor General population HCW healthcare healthcare worker higher risk hospitalised Hospitalized identify in-hospital mortality intensive care interquartile range Laboratory less lower mortality Male sex Mortality multivariate logistic regression no difference not carry Occurrence Patient Prognosis radiological finding registry Respiratory Support Result selected Sepsis Sociodemographic Spain Spanish survival Treatment was performed with COVID-19 women worse prognosis [DOI] 10.1371/journal.pone.0247422 PMC 바로가기 [Article Type] Clinical Trial
Risk of COVID-19 hospital admission and COVID-19 mortality during the first COVID-19 wave with a special emphasis on ethnic minorities: an observational study of a single, deprived, multiethnic UK health economyObservational Study Published on 2021-02-172022-10-05 Journal: BMJ Open [Category] 임상, [키워드] 95% CI Admission age Asian association black Cohort Community Comorbidities Comorbidity Complete COVID-19 COVID-19 admission COVID-19 mortality death deaths defined Deprivation died discharge Epidemiology ethnic group Factor Gender Health highlighting hospital Hospital admission impacted In-hospital death Local lower mortality Mortality Multimorbidity NCA Non-COVID-19 observational study outcome outcomes Patient populations public health risk risk factor Risk factors South Asian Variation [DOI] 10.1136/bmjopen-2020-046556 PMC 바로가기 [Article Type] Observational Study