Manufacturing and Management of CAR T-Cell Therapy in “COVID-19’s Time”: Central Versus Point of Care Proposals"COVID-19 시대"의 CAR T-세포 치료제 제조 및 관리: 중앙 대 진료 현장 제안Review Published on 2020-10-152022-09-11 Journal: Frontiers in Immunology [Category] MERS, SARS, 바이오마커, 진단, [키워드] administration adoptive cell immunotherapy affected antigen receptor attenuate CAR caused Cell cell therapies chimeric antigen receptor COVID-19 pandemic criteria curative treatment cytokine Cytokine release syndrome focus good manufacturing practice Health Service Health services hematologic hospital hospitalized patients Infection Intervention malignancies manufacturing process neurotoxicity Patient patient selection pharmaceutical industry Point Prevent Prophylactic reduction resource respiratory Safe SARS-CoV-2 SARS-CoV-2 coronavirus saturation Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus-2 supply chains T-cell T-cells Therapies therapy Tocilizumab Treatment [DOI] 10.3389/fimmu.2020.573179 PMC 바로가기 [Article Type] Review
The presentation of spontaneous splenic rupture in a COVID-19 patient: a case reportCase Report Published on 2020-10-022022-10-28 Journal: BMC Surgery [Category] COVID-19, MERS, SARS, [키워드] abdomen abdominal pain bleeding Blood Case report contrary COVID-19 Diseases distress emergency condition epigastrium Fever hematological Hospitalization Inflammatory diseases lethargy malignancies nausea Operating room pathology Patient patient reported patients with COVID-19 performed Rasht reported risk rupture spleen Splenic SSR surgery Symptoms the patient transferred trauma was performed [DOI] 10.1186/s12893-020-00887-5 PMC 바로가기 [Article Type] Case Report
Prevention of COVID-19 infection in a pediatric oncology ward in Wuhan우한 소아종양병동 코로나19 감염 예방Article Published on 2020-10-012022-09-11 Journal: Pediatric blood & cancer [Category] MERS, SARS, 진단, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Admission Admitted Patient admitted patients all the patients Anal analyzed Antibacterial antibody Antifungal treatment Antiviral agents Caregivers carried change Chemotherapy Chest Chest computerized tomography Chest CT image Chest CT images children clinical feature Computerized tomography coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 infection Department described Hematologic malignancy hematology hospital IgM and IgG Infection Inpatient Isolation malignancies malignancy measure nasopharyngeal nucleic acid nucleic acid testing oncology Oropharyngeal Patient pediatric Pediatric patient Pediatric patients Pneumonia presenting prevented prevention Protective Quantitative respiratory SARS-CoV-2 Screening severe acute respiratory syndrome Coronavirus symptomatic patient Symptomatic patients Symptoms the patient Tongji Hospital Viral Viral pneumonia was performed Wuhan [DOI] 10.1002/pbc.28424 PMC 바로가기 [Article Type] Article
Important updates from the AACR virtual meeting: COVID-19 and cancerConference Report Published on 2020-09-182022-10-31 Journal: Future Science OA [Category] COVID-19, [키워드] Abstract Breast cancer Cancer Cancer patients COVID-19 Cytokine release syndrome Efficacy Epidemiology hematologic inhibitor lung cancer males malignancies Melanoma morbidity and mortality older patient oncology patients with COVID-19 phase Prostate cancer ruxolitinib treat Trial Vaccine [DOI] 10.2144/fsoa-2020-0132 PMC 바로가기 [Article Type] Conference Report
Cancer progression in COVID-19: integrating the roles of renin angiotensin aldosterone system, angiopoietin-2, heat shock protein-27 and epithelial mesenchymal transitionShort Communication Published on 2020-09-092022-10-31 Journal: ecancermedicalscience [Category] COVID-19, [키워드] Abnormalities ACE-2 activated Acute inflammation acute respiratory syndrome addition affected Angiogenesis angiopoetin-2 angiotensin Angiotensin 1-7 Anti-inflammatory Apoptosis blood vessel Cancer cancer cell cancer progression cancers cause cell proliferation cells cellular cellular entry Comorbidities coronavirus disease COVID-19 COVID-19 patient Cytokine storm Diffuse alveolar damage disrupt downregulation Effect EMT epithelial Express follow-up study form growth healthcare Heat shock HSP-27 phosphorylation hypothesise immune system induce infections Inflammatory Intussusceptive angiogenesis kidney malignancies Metastasis organ damage outbreak pandemic pathway Pathways Patient Phosphorylation pro-inflammatory progression proliferative Protein RAAS raise receptor responsible risk severe disease survivor susceptibility susceptible the disease tumour upregulated while [DOI] 10.3332/ecancer.2020.1099 PMC 바로가기 [Article Type] Short Communication
Comprehensive elaboration of the cGAS-STING signaling axis in cancer development and immunotherapyReview Published on 2020-08-272022-10-30 Journal: Molecular Cancer [Category] COVID-19, [키워드] Activation adaptive agonist agonists antimicrobial immunity Antitumor response cancer development cGAS-STING Combination Comprehensive conserved Critical cyclic cytokine detect DNA downstream Evidence IFNs Immunity Immunotherapy Inflammatory cytokines innate immune system Innate immunity interferon involved malignancies mechanism microbial Pathogens pathway phenotype regulated Signaling signaling pathway STING agonists type I IFNs type I interferon [DOI] 10.1186/s12943-020-01250-1 PMC 바로가기 [Article Type] Review
CAR T-cell treatment during the COVID-19 pandemic: Management strategies and challengesReview article Published on 2020-08-012022-10-05 Journal: Current research in translational medicine [Category] SARS, 치료법, [키워드] acute respiratory syndrome affecting CAR CAR-T CAR-T therapy CAR-T treatment caused chimeric antigen receptor Chimeric antigen receptor T-cells coronavirus coronavirus disease COVID-19 COVID-19 pandemic Cytokine release syndrome Disease progression Factor healthcare service hematologic Hematological malignancies Immunocompromised Infection malignancies pandemic Patient Prevent Protective Relapsed/refractory hematological malignancies SARS-CoV-2 T-cell T-cells therapy Treatment [DOI] 10.1016/j.retram.2020.06.003 [Article Type] Review article
SARS-CoV-2 infection associated with micturition syncope Our experience with 4 case reports4900 Published on 2020-07-312022-10-30 Journal: Medicine [Category] COVID-19, SARS, [키워드] authors blood pressure Case report cause caused Clinical course Corticosteroid coughing COVID-19 COVID-19 patient Department described diagnosed with COVID-19 disorders dysfunction Emergency Evolution Hospitalization Hospitalized Infection Infectious disease knowledge Local Loss of consciousness malignancies mechanism medication micturition micturition syncope national guidelines neurological impairment occur Other Patient pulmonary hypertension real time reported Romania RT-PCR SARS-CoV-2 SARS-COV-2 infection short duration Stage Syncope Treatment urination Vasoactive was performed were excluded [DOI] 10.1097/MD.0000000000021512 PMC 바로가기 [Article Type] 4900
Recommendations from the Canadian Association of Head and Neck Surgical Oncology for the Management of Head and Neck Cancers during the COVID-19 pandemicReview Published on 2020-07-292022-10-29 Journal: Journal of Otolaryngology - Head & Neck Surgery [Category] COVID-19, SARS, [키워드] asymptomatic patients Canada Cancer Care Clinical practice guideline COVID 19 patients COVID-19 COVID-19 pandemic COVID19 develop Diagnosis Disease progression enhanced Evidence extreme Follow-up global pandemic head Head and neck oncology Head and neck surgery Health Health care worker healthcare help high risk Hospital admissions identify increase in initial Intervention involved limit majority malignancies Modification N95 mask Neck oncologist oncology pandemic Patient patients performed Personal protective equipment positive PPE Practitioner predicted recommendation reduce reduced Region resource Respirator risk SARS-CoV-2 SARS-CoV-2 virus surgeon surgical symptomatic Transmission Treatment [DOI] 10.1186/s40463-020-00448-z PMC 바로가기 [Article Type] Review
Could hemophagocytic lymphohistiocytosis be the core issue of severe COVID-19 cases?Opinion Published on 2020-07-152022-10-28 Journal: BMC Medicine [Category] COVID-19, SARS, [키워드] “cytokine storm” acute respiratory distress acute respiratory syndrome ARDS caused characterized Clinical characteristics clinical symptom conditions coronavirus Coronavirus disease 2019 cough Course COVID-19 cytokine release death disease Diseases Dyspnea fatigue Fever hemophagocytic lymphohistiocytosis HLH hyperinflammation Hyperinflammatory syndrome identify immunosuppressive IMPROVE Infection infections Inflammatory Inflammatory response Laboratory test life-threatening majority malignancies mild symptoms multi-organ failure myalgia outcomes Pathogenesis pathogenesis of SARS-CoV-2 Patient patients with COVID-19 Pneumonia rheumatological SARS-CoV-2 screened Severe case severe COVID-19 syndrome therapy triggered [DOI] 10.1186/s12916-020-01682-y PMC 바로가기 [Article Type] Opinion