Medical Research Council – Page 10 – Communicable Diseases Research

Evaluating the effects of cardiometabolic exposures on circulating proteins which may contribute to severe SARS-CoV-2

심각한 SARS-CoV-2에 기여할 수 있는 순환 단백질에 대한 심혈관 대사 노출의 영향 평가

Research Paper

Published on 2021-02-032022-09-11
Journal: EBioMedicine [Category] MERS, 바이오마커, 변종,

Impact of the COVID-19 pandemic on the detection and management of colorectal cancer in England: a population-based study

COVID-19 대유행이 영국의 대장암 발견 및 관리에 미치는 영향: 인구 기반 연구

Articles

Published on 2021-01-152022-09-10
Journal: The Lancet. Gastroenterology & Hepatology [Category] Fulltext, SARS, 진단, 치료기술, 치료제,

[키워드] 2019 95% CI achievement Admitted Patient average calculated Cancer Cancer Research UK Care Colorectal cancer Course courses COVID-19 COVID-19 pandemic dataset datasets diagnosed difference Digital drop England Evidence expected finding funding greater Health Data Research UK Impact increase in investigated Laparoscopic surgery management Medical Research Council Modification modifications monitoring monthly rate NHS number number of colonoscopies Oxford pathway Patient percentage pressure proportion proportions Public Health England Radiotherapy receiving rectal rectal cancer reduction reduction in reductions in regimens remained returned second wave secondary service stoma surgery surgical sustained target time treated Treatment Volume
[DOI] 10.1016/S2468-1253(21)00005-4 PMC 바로가기 [Article Type] Articles

Core Outcome Measures for Trials in People With Coronavirus Disease 2019: Respiratory Failure, Multiorgan Failure, Shortness of Breath, and Recovery

코로나바이러스 질병 2019 환자의 시험에 대한 핵심 결과 측정: 호흡 부전, 다기관 부전, 숨가쁨 및 회복

Clinical Investigations

Published on 2021-01-052022-09-11
Journal: Critical Care Medicine [Category] 임상,

[키워드] 5-point Likert scale absence activities activity applicability assessment capture Care clinical clinical care clinical trial Consensus Consistency content content validity core coronavirus coronavirus disease Coronavirus disease 2019 coronavirus disease 2019) country Critical care de novo Decision-making defined Digital Digital Content domain Evidence extreme failure feasible fluctuation Health Health Organization Inclusion Infection International measure Measures Medical Research Council Mortality multiple organ failure Organ failure outcome outcome measure outcome measures participant Patient patients Pragmatic professionals recall respiratory Respiratory failure Respiratory Support scale Sepsis Sequential Organ Failure Assessment severity Shortness of breath Symptoms text Trial Validity World Health Organization
[DOI] 10.1097/CCM.0000000000004817 PMC 바로가기 [Article Type] Clinical Investigations

Physical Therapist Management of COVID-19 in the Intensive Care Unit: The West China Hospital Experience

Observational Study

Published on 2021-01-042022-10-05
Journal: Physical therapy [Category] 임상,

[키워드] airway Antiviral appear Borg category center China clearance clinical Cohort Commission Comorbidities Comorbidity Coronavirus disease 2019 COVID-19 defined diagnosed with COVID-19 directive discharge disease experience expiratory function functional Health Health care system hospital hospitals ICU immunoregulation index Inspiratory Muscle Training intensive care Intervention majority management Maximal Inspiratory Pressure mechanical ventilation median Medical Research Council Mobility muscle National Health Commission Oscillatory Positive End-Expiratory Pressure outcome outcome measure outcomes Patient patients patients with COVID-19 physical Physical function Physical therapist Positive end-expiratory pressure predicted Public rehabilitation remained required Safe scale score Supportive treatment Test the patient therapist therapy verbal were excluded West
[DOI] 10.1093/ptj/pzaa198 PMC 바로가기 [Article Type] Observational Study

Detecting COVID-19 infection hotspots in England using large-scale self-reported data from a mobile application: a prospective, observational study

모바일 애플리케이션의 대규모 자체 보고 데이터를 사용하여 영국의 COVID-19 감염 핫스팟 감지: 전향적, 관찰 연구

Observational Study

Published on 2021-01-012022-09-11
Journal: The Lancet. Public Health [Category] Fulltext, MERS, 임상, 치료제,

[키워드] 95% CI age assessment assessments calculated chain change chronic chronic disease community infection community transmission complementary Council country COVID COVID Symptom Study app COVID-19 COVID-19 infection dataset Department detect Disease surveillance effective Engineering England estimate foundation Government granular healthy heart help highest highlight hotspot identify incidence incidence of COVID-19 incidence rate incidence rates increases in information Intervention Local Logistic regression Markov Markov chain Medical Research Council National observational study office ONS pandemic PCR tests Poisson Prevalence provided recorded Region reported Reproduction number resource RT-PCR RT-PCR test RT-PCR tests Science sensitivity Society spread of COVID-19 Statistics survey Swab Swab test Symptom Symptoms test results the disease Wellcome Trust Zoe Global
[DOI] 10.1016/S2468-2667(20)30269-3 PMC 바로가기 [Article Type] Observational Study

Six-Month Pulmonary Impairment after Severe COVID-19: A Prospective, Multicentre Follow-Up Study

Observational Study

Published on 2021-01-012022-10-05
Journal: Respiration [Category] 임상,

[키워드] 6-min walking test Abnormalities acute respiratory syndrome administration age airway Asthma caused chest imaging chest X-ray collected Comorbidity coronavirus coronavirus disease COVID-19 defined Diagnosis diffusion capacity discharge Dyspnoea enrolled Follow-up functional Future highest Hospitalization identify impairment interquartile range invasive logistic regression model Lung disease median Medical Research Council mMRC MONITOR multicentre observation Observational cohort study parameter Patient patients patients hospitalized Physical examination Pneumonia positive Prophylactic Prospective protective factor pulmonary pulmonary fibrosis radiological radiology Radiology and other imaging reported Respiratory function tests SARS-CoV-2 SARS-CoV-2 pneumonia stratified ventilatory ventilatory support
[DOI] 10.1159/000518141 PMC 바로가기 [Article Type] Observational Study

Quality of life and long-term outcomes after hospitalization for COVID-19: Protocol for a prospective cohort study (Coalition VII)

COVID-19로 인한 입원 후 삶의 질과 장기적인 결과: 전향적 코호트 연구를 위한 프로토콜(연합 VII)

Multicenter Study

Published on 2021-01-012022-09-10
Journal: Revista Brasileira de Terapia Intensiva [Category] MERS, 임상,

[키워드] activity acute illness all-cause mortality Anxiety approved association Brazil Cardiovascular events caused Characteristics Coalition conferences COVID-19 COVID-19 treatment Daily daily living demographic characteristics Depression disorder dissemination Dyspnea Effect Ethics ethics committee Factor FIVE functional Functional status Generalized Health Hospitalization Impact include Instrumental life Medical Research Council Medidas de resultados relatados pelo paciente Modified Medical Research Council Dyspnea Scale multicenter outcome outcomes Patient-reported outcome measures peer-reviewed performed physical Posttraumatic Stress posttraumatic stress disorder premorbid Primary outcome prospective cohort study Qualidade de vida Quality Quality of life randomized clinical trial Research Ethics Research Ethics Committee SARS-CoV-2 SARS-COV-2 infection scale secondary Study protocol survivor Symptom utility variable variables ventilatory support Visual
[DOI] 10.5935/0103-507X.20210003 PMC 바로가기 [Article Type] Multicenter Study

Renin–angiotensin system blockers and susceptibility to COVID-19: an international, open science, cohort analysis

Articles

Published on 2020-12-172022-10-31
Journal: International Journal of Environmental Research an [Category] COVID-19,

[키워드] 95% CI ACEi ACEIs Acute kidney injury acute respiratory distress Affair Affect Algorithm analyses angiotensin receptor blocker approach ARB ARBs association baseline blocker calibrated CCBs center Characteristics clinically Cohort cohort analysis Columbia University Combination combination therapy Comparisons Control COVID-19 COVID-19 diagnosis COVID-19 in patient data-driven decrease defined demonstrated Department determine development diuretics Effects Electronic health record enzyme European experiment finding funding generalisability generate hazard ratio heterogeneity hospital Hospital admission hypertension identify increased risk inhibitor International IQVIA janssen Korean lower risk Medical Research Council medications meta-analysed Ministry of Health monotherapy negative control network no significant difference observational study Older outcome partnership Patient patient cohort Pneumonia receiving Registered renin–angiotensin system risk risk of COVID-19 Sepsis South Spain susceptibility syndrome System Treatment USA user veteran Welfare Wellcome Trust with COVID-19
[DOI] 10.1016/S2589-7500(20)30289-2 PMC 바로가기 [Article Type] Articles

Comparison of molecular testing strategies for COVID-19 control: a mathematical modelling study

코로나19 통제를 위한 분자 테스트 전략 비교: 수학적 모델링 연구

Comparative Study

Published on 2020-12-012022-09-12
Journal: The Lancet. Infectious Diseases [Category] MERS, SARS, 진단,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Antibody test antibody tests approach assays Contact Contact tracing coronavirus country Coverage COVID-19 COVID-19 pandemic defined diagnostic tests effective Effectiveness ELISA examined expected false negatives finding foundation funding group groups health-care identify Immunity Immunity passports implication individual Infection infectiousness Isolation laboratory-confirmed mathematical mathematical model Mathematical modelling Medical Research Council molecular New PCR test PCR testing population immunity protocols quarantine Rapid diagnostic test reduce reducing reduction reduction in reductions reported Reproduction number respiratory SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 transmission self-isolate Self-isolation sensitivity severe acute respiratory syndrome Coronavirus specificity Symptom symptom onset symptomatic individual symptomatic individuals Symptoms Timeliness trace Transmission Weekly WHO with COVID-19
[DOI] 10.1016/S1473-3099(20)30630-7 PMC 바로가기 [Article Type] Comparative Study

COVID-19 among people experiencing homelessness in England: a modelling study

영국 노숙자 사이의 COVID-19: 모델링 연구

Articles

Published on 2020-12-012022-09-06
Journal: The Lancet. Respiratory Medicine [Category] Communicable Disease, COVID-19, MERS, SARS,

[키워드] 95% prediction interval 97·5% quantiles acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Admissions attack rate avoidance calibrated the model Comorbidities coronavirus COVID-19 death deaths discrete-time Markov chain model England finding First wave funding General population health-care use Homeless population homelessness Hospital admission Hospital admissions ICU ICU admission in some incidence individual individuals Infection infection control infectious intensive care intensive care unit lead lifted Markov chain measure Medical Research Council night shelters number of deaths occurred outbreak pandemic people experiencing homelessness Prevalence preventive measure preventive measures PROTECT reported respiratory risk of transmission SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections scenario second wave severe acute respiratory syndrome Coronavirus susceptible the median Transmission
[DOI] 10.1016/S2213-2600(20)30396-9 PMC 바로가기 [Article Type] Articles