A Novel Potentially Recombinant Rodent Coronavirus with a Polybasic Cleavage Site in the Spike ProteinArticle Published on 2021-08-252023-06-14 Journal: Journal of Virology [Category] MERS, [키워드] coronavirus Genomics polybasic cleavage site Recombination rodents [DOI] 10.1128/JVI.01173-21 PMC 바로가기
Editorial: Origin and Evolution of Hepatitis VirusesArticle Published on 2021-08-252023-08-30 Journal: Frontiers in Microbiology [Category] E형 간염, [키워드] Genotype Geographic distribution host shift Phylogeny Recombination resistance Subgenotype [DOI] 10.3389/fmicb.2021.740255 PMC 바로가기
A novel SARS-CoV-2 related coronavirus with complex recombination isolated from bats in Yunnan province, ChinaResearch Article Published on 2021-08-222022-10-31 Journal: Emerging Microbes & Infections [Category] COVID-19, SARS, [키워드] Amino acid Analysis bat bats beta-CoV China collected Combined complex coronavirus Coronaviruses COVID-19 pandemic Evolution Genes Genome genomic genomic region highest homology identity indicated intestinal less manifested mechanism new SARS-CoV-2 NGS Novel coronavirus nucleotide Previous studies RaTG13 Receptor binding domain Recombination recombination event regions related viruses SARS-CoV SARS-CoV-2 SARS-CoV-2 genome SARSr-CoV Sequence alignment Sequencing Spread Strains the SARS-CoV-2 thought triggered virus [DOI] 10.1080/22221751.2021.1964925 PMC 바로가기 [Article Type] Research Article
Patterns of within-host genetic diversity in SARS-CoV-2SARS-CoV-2의 숙주 내 유전적 다양성 패턴Research Article Published on 2021-08-132022-09-10 Journal: eLife [Category] MERS, SARS, 변종, 치료기술, [키워드] accumulation addition allele frequencies allele frequency analyses Analysis caution Co-infection consensus genome convergent evolution COVID-19 pandemic damage detectable determine develop Diversity driving eLife epidemiological Evolution example Factor focus genetic code genetic diversity genetic material Genetic testing genetic tests genetics globe Government Health help homoplasies Host hosts identify Impact individual individuals infected individuals Infection information Intervention Lineage MONITOR monitoring mutate Mutation mutation rate mutational hotspot Mutational hotspots mutational spectrum mutations Nonsense mutations occurred Other pandemic pattern Phylogenetic predict Prevent public health Recombination reconstruction Recurrent Replication responsible RNA SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 pandemic SARS-CoV-2 virus SARS-CoV-2 viruses Scientific community sequenced Sequencing Spectrum Spread spreads strain superinfection the SARS-CoV-2 the SARS-CoV-2 genome Transmission transmission of SARS-CoV-2 Vaccines variant variants Viral viral samples virus viruses while within-host [DOI] 10.7554/eLife.66857 PMC 바로가기 [Article Type] Research Article
Update on the Phylodynamics of SADS-CoVArticle Published on 2021-08-112022-10-29 Journal: International Review of Cell and Molecular Biology [Category] COVID-19, [키워드] alphacoronavirus bat caused Chinese coronavirus CoV CoVs discrepancy enteric Epidemiology genetic diversity Health heterogeneous high recombination hosts Human Hypothesis infect lack marker molecular Occurrence outbreak pathogen performed phylodynamics Phylogenetic Recombination recombination event reported reservoir Result Transmission viruses whole genome zoonotic infection [DOI] 10.3390/life11080820 PMC 바로가기 [Article Type] Article
Recombination and lineage-specific mutations linked to the emergence of SARS-CoV-2SARS-CoV-2의 출현과 관련된 재조합 및 계통 특이적 돌연변이Research Published on 2021-08-062022-09-10 Journal: Genome Medicine [Category] MERS, SARS, 변종, [키워드] accompanied adaptation affecting affinity Algorithm allele alleles analyses ancestor ancestors Betacoronavirus Betacoronavirus genus binding binding affinity clade event Evidence evidence of hACE2 helix host cell Human human ACE2 humans in silico include indicate infect information insertion interact MERS MERS-CoV Mutation Phylogenetic Protein protein level RBD receptor Receptor binding affinity Receptor binding domain receptors Recombination recombination event reconstruction responsible Result resulting SARS-CoV SARS-CoV-2 sequence significantly Spike protein strain supplementary material the RBD the Spike variant variants Viral virus viruses was used zoonosis zoonotic [DOI] 10.1186/s13073-021-00943-6 PMC 바로가기 [Article Type] Research
Animal Coronavirus Diseases: Parallels with COVID-19 in HumansReview Published on 2021-07-302022-10-28 Journal: Viruses [Category] COVID-19, SARS, [키워드] acute respiratory syndrome animal animal coronavirus caused Clinical signs complement coronavirus Coronavirus disease 2019 Coronaviruses COVID-19 COVID-19 pandemic Critical described Diagnosis disease DIVA effective vaccine genome organization handling Human humans Immunopathogenesis Intensive Novel coronavirus Outbreaks pathophysiological mechanism Perspective public health Recombination recorded Research SARS-CoV-2 subject Transmission Treatment viral shedding viruses with COVID-19 [DOI] 10.3390/v13081507 PMC 바로가기 [Article Type] Review
Molecular Determinants of SARS-CoV-2 VariantsArticle Published on 2021-07-272023-06-15 Journal: Trends in microbiology [Category] MERS, SARS, [키워드] COVID-19 Recombination Replication SARS-CoV-2 variants [DOI] 10.1016/j.tim.2021.07.002 PMC 바로가기
Metagenomic identification of a new sarbecovirus from horseshoe bats in EuropeArticle Published on 2021-07-192022-10-04 Journal: Scientific Reports [Category] SARS, 변종, 유전자 메커니즘, [키워드] Amino acid Asian bat bats binding ability Co-infection COVID-19 pandemic Critical distribution Europe extreme hACE2 highlight Homologous recombination homology Host Mutation Preventing Receptor binding domain receptor binding motif Recombination sarbecovirus SARS-CoV SARS-CoV-2 sequenced the spike protein thought transmission of SARS-CoV-2 unlikely vaccination Viral reservoirs virus while zoonotic [DOI] 10.1038/s41598-021-94011-z PMC 바로가기 [Article Type] Article
Recombinant SARS-CoV-2 genomes circulated at low levels over the first year of the pandemicResearch Article Published on 2021-07-152022-10-28 Journal: Virus Evolution [Category] COVID-19, [키워드] Adjusting Analysis approach Betacoronavirus Characteristics characterized circulating circulation clade clades Co-infection coronavirus coronavirus 2 criteria D614G de novo mutation determine E484K effort Evidence feasibility generate Genetic Genome Genotype hotspot indicated L452R Lineage lineages majority marker MONITOR Mutation N501Y pandemic parental phenotypic Phylogenetic analysis predicted Probability recombinant recombinants Recombination Region respiratory SARS-CoV-2 SARS-CoV-2 genome sequence strain subset Substitution Support the SARS-CoV-2 genome Transmissibility unique USA Variation virulence virus while [DOI] 10.1093/ve/veab059 PMC 바로가기 [Article Type] Research Article