Symptomatic SARS-COV-2 reinfection: healthcare workers and immunosuppressed individuals at high riskResearch Published on 2021-09-062022-10-28 Journal: BMC Infectious Diseases [Category] COVID-19, SARS, [키워드] analyzed conducted confirmed case COVID-19 disease effort elapsed Factor greater Health personnel healthcare worker high risk identify Immunosuppressed implication incidence individual Mild older subject Patient populations public health reduced risk reduction Reinfection renal replicated Result retrospective cohort study risk Risk reduction behavior severe acute respiratory syndrome coronavirus 2 Spread symptomatic [DOI] 10.1186/s12879-021-06643-1 PMC 바로가기 [Article Type] Research
Chronic Diseases as a Predictor for Severity and Mortality of COVID-19: A Systematic Review With Cumulative Meta-AnalysisMedicine Published on 2021-09-012022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] acute respiratory distress Admission Aggressive Asthma Cancer Cerebrovascular disease chronic chronic disease Chronic diseases chronic liver disease chronic renal disease coronavirus disease country COVID-19 COVID-19 mortality COVID-19 pandemic COVID-19 patient COVID-19 patients COVID-19 severity cumulative cumulative meta-analysis Deterioration global healthcare greater higher risk hypertension ICU ICU admission identify index intensive care Meta-analysis Mortality Nursing obesity observational study Obstructive pandemic Patient patients with COVID-19 performed Predictive Probability pulmonary disease reduced risk review risk factor risk of bia searched severe COVID-19 severe symptom severity Symptom syndrome systematic review Web of Science [DOI] 10.3389/fmed.2021.588013 PMC 바로가기 [Article Type] Medicine
Timing of corticosteroids impacts mortality in hospitalized COVID-19 patientsObservational Study Published on 2021-09-012022-10-04 Journal: Internal and Emergency Medicine [Category] 임상, [키워드] 95% CI absence Admission Analysis analyzed benefit collected coronavirus Corticosteroid corticosteroid therapy corticosteroid treatment Corticosteroids COVID-19 COVID-19 patients death demographic evaluated first dose group Hospitalization Hospitalized hospitalized COVID-19 patient hospitalized COVID-19 patients hospitalized patient Impact in-hospital mortality initial initiated Invasive mechanical ventilation Laboratory lower risk mechanically ventilated patient Mortality multivariable Oxygen therapy Patient patients receiving oxygen quantified receiving reduced risk Regression analyses requiring supplemental oxygen symptom onset the patient the timing therapy time time interval Timing Treatment variable was related [DOI] 10.1007/s11739-021-02655-6 PMC 바로가기 [Article Type] Observational Study
Metformin use is associated with a reduced risk of mortality in patients with diabetes hospitalised for COVID-19Observational Study Published on 2021-09-012022-10-05 Journal: Diabetes & metabolism [Category] 임상, [키워드] addressed Admission Anti-inflammatory applied approach association complications COVID-19 death diabetes Diabetic feature French had more hospitalised immunosuppressive effects intubation Kaplan-Meier survival curve Logistic regression analysis lower risk Mechanical mechanical ventilation metformin Mortality mortality rate occurred Odds ratio outcome Patient patients with diabete Prevalence primary endpoint Primary outcome Probability Prognosis Propensity score reduced risk reported tracheal Treatment Type type 2 diabete type 2 diabetes Weighting [DOI] 10.1016/j.diabet.2020.101216 PMC 바로가기 [Article Type] Observational Study
Hemodialysis Patients Make Long-Lived Antibodies against SARS-CoV-2 that May Be Associated with Reduced ReinfectionObservational Study Published on 2021-09-012022-10-05 Journal: Journal of the American Society of Nephrology : JA [Category] SARS, 임상, [키워드] acute respiratory syndrome antibody Antibody Response Cohort Coronavirus-2 COVID-19 Evolution First wave Hemodialysis Infection pandemic Patient PCR-confirmed Protective receiving reduced risk SARS-CoV-2 SARS-CoV-2 antibodies SARS-CoV-2 antibody SARS-COV-2 infection Spike protein subsequent the SARS-CoV-2 [DOI] 10.1681/ASN.2021020188 PMC 바로가기 [Article Type] Observational Study
Oxygen Sparing Effect of Bacteriotherapy in COVID-19COVID-19에서 세균 요법의 산소 절약 효과Article Published on 2021-08-232022-09-10 Journal: Nutrients [Category] MERS, 치료제, [키워드] activated addition Administered Analysis Azithromycin bacteriotherapy Blood blood gas Blood level blood levels collected COVID-19 Effect enzyme Enzymes Gas exchange heparin hypoxia intestinal cells intestine lesion lesions lung lung involvement Lungs mechanism nitric oxide Non-invasive observation period organ organs other organs oxygen Oxygen consumption Oxygen therapy Oxygenation parameter Patient performed presenting Probiotics receiving reduce reduced risk Remdesivir reported Respiratory failure SARS-CoV-2 infected patient SARS-CoV-2 infected patients severe COVID-19 patient severe COVID-19 patients significantly increased SLAB51 sparing Standard therapy subject survival Treatment [DOI] 10.3390/nu13082898 PMC 바로가기 [Article Type] Article
Metformin in Patients With COVID-19: A Systematic Review and Meta-AnalysisMedicine Published on 2021-08-192022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] 95% CI 95% confidence interval age association benefit Chinese Cochrane Library conducted coronavirus disease COVID-19 COVID-19 mortality COVID-19 patient COVID-19 patients Critical Deterioration Diabetic effect sizes Effects Hospitalization hospitalized COVID-19 patients identify influence intubation literature Meta-analysis metformin Mortality multivariate model observational study outcome outcomes pandemic Participants Primary outcome public health Randomized controlled trial reduced risk Registered review risk Risk of bias searched secondary outcome shown statistically significant subgroup analysis were used [DOI] 10.3389/fmed.2021.704666 PMC 바로가기 [Article Type] Medicine
Donor genetic variants in interleukin-6 and interleukin-6 receptor associate with biopsy-proven rejection following kidney transplantationArticle Published on 2021-08-132022-10-04 Journal: Scientific Reports [Category] 신약개발, [키워드] Allograft association C-allele center DNA Donor female organ Genetic variant Genotype Groningen IL-6 receptor IL6 IL6R Immunogenetics Impact increased risk independent interleukin-6 interleukin-6 receptor Interleukins kidney male organ morbidity Netherland Observational cohort study Occurrence performed polymorphism Prognostic marker reduced risk rejection renal renal replacement therapy rs2228145 rs8192284 Single nucleotide polymorphism SNP SNPs university [DOI] 10.1038/s41598-021-95714-z PMC 바로가기 [Article Type] Article
Sleeping for two: study protocol for a randomized controlled trial of cognitive behavioral therapy for insomnia in pregnant women2인용 수면: 임산부의 불면증에 대한 인지 행동 요법의 무작위 대조 시험을 위한 연구 프로토콜Study Protocol Published on 2021-08-122022-09-10 Journal: Trials [Category] MERS, SARS, 임상, [키워드] actigraphy aims assessment behavioral therapy build CBT child health children cognitive cognitive behavioral therapy conducted consequence COVID-19 pandemic death Depression developmental Diagnosis distress during pregnancy Effectiveness ENhance enrolled evaluate finding gestation Health IMPROVE individual Insomnia Intervention lead Long terms mother occur open parallel group physical distancing Pregnancy pregnant women Preterm birth Primary outcome problems Randomized controlled trial RCT reduce reduced risk reducing repeated measure repeated measures Research risk Secondary outcomes Sleep Sleep disturbance Sleep disturbances Study protocol Symptom symptom severity symptoms of depression Tau telehealth therapy treat Treatment treatment as usual Trial Trial registration Two-arm used to evaluate [DOI] 10.1186/s13063-021-05498-w PMC 바로가기 [Article Type] Study Protocol
The impact of tocilizumab on respiratory support states transition and clinical outcomes in COVID-19 patients. A Markov model multi-state studyCOVID-19 환자의 호흡 지원 상태 전환 및 임상 결과에 대한 토실리주맙의 영향. 마르코프 모델 다중 상태 연구Observational Study Published on 2021-08-122022-09-12 Journal: PLoS ONE [Category] 임상, 진단, [키워드] 95% CI Analysis approach benefit Clinical outcome clinical trials contributing to COVID pneumonia COVID-19 patients death Decision making disease disease stage Endpoint heterogeneous hospital IMV invasive Invasive mechanical ventilation management Markov Mortality NIV no respiratory support Non-invasive non-invasive ventilation observational study oxygen Oxygen therapy Patient positive Prevalence Probability randomized clinical trial reduced risk Respiratory Support Result sequence Support switching Time to recovery Tocilizumab tocilizumab administration treated was used [DOI] 10.1371/journal.pone.0251378 PMC 바로가기 [Article Type] Observational Study