sequencing data – Page 10 – Communicable Diseases Research

Reliable and accurate diagnostics from highly multiplexed sequencing assays

고도로 다중화된 시퀀싱 분석에서 신뢰할 수 있고 정확한 진단

Article

Published on 2020-12-102022-09-01
Journal: Scientific Reports [Category] MERS, SARS, 진단,

First Phylogenetic Analysis of Malian SARS-CoV-2 Sequences Provides Molecular Insights into the Genomic Diversity of the Sahel Region

Article

Published on 2020-11-022022-10-28
Journal: Viruses [Category] COVID-19, SARS,

[키워드] Analysis caused China clade coronavirus country Diversity effort Human independent insight isolates Mali pandemic pandemic of COVID-19 Patient Phylogenetic analysis positive Region Sahel SARS-CoV-2 Screening sequence Sequencing sequencing data spread to virus WGS whole genome whole genome sequence Wuhan
[DOI] 10.3390/v12111251 PMC 바로가기 [Article Type] Article

Systematic analysis of ACE2 and TMPRSS2 expression in salivary glands reveals underlying transmission mechanism caused by SARS-CoV-2

타액선에서 ACE2 및 TMPRSS2 발현에 대한 체계적인 분석을 통해 SARS-CoV-2로 인한 근본적인 전염 메커니즘 밝혀

Article

Published on 2020-11-012022-09-11
Journal: Journal of medical virology [Category] SARS, 유전자 메커니즘, 치료기술,

[키워드] ACE2 acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 age Analysis analyzed angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme 2 caused Cell collected component components coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 Data analysis dataset distribution epithelial cells expressed expressing expression expression level expression levels fatality global pandemic group Health healthy indicated mechanism men and women mice organ other tissue other tissues parotid gland proportion proportions protease researcher respiratory reveal RNA sequence Saliva salivary salivary gland salivary glands SARS-CoV-2 sequencing data Serine serine protease severe acute respiratory syndrome Coronavirus significant difference significant differences single-cell The Genotype-Tissue Expression threat tissue TMPRSS TMPRSS2 TMPRSS2 expression Transcriptome Transmission Viral Viral load were expressed
[DOI] 10.1002/jmv.26045 PMC 바로가기 [Article Type] Article

Genopo : a nanopore sequencing analysis toolkit for portable Android devices

Article

Published on 2020-09-292022-10-31
Journal: Communications Biology [Category] COVID-19, SARS,

Potential role of cellular miRNAs in coronavirus-host interplay

Bioinformatics

Published on 2020-09-142022-10-28
Journal: PeerJ [Category] COVID-19,

Adaptive immune responses to SARS-CoV-2 infection in severe versus mild individuals

Article

Published on 2020-08-142022-10-04
Journal: Signal Transduction and Targeted Therapy [Category] Fulltext, MERS, 변종,

Integrative analysis of miRNA and mRNA sequencing data reveals potential regulatory mechanisms of ACE2 and TMPRSS2

miRNA 및 mRNA 시퀀싱 데이터의 통합 분석은 ACE2 및 TMPRSS2의 잠재적인 조절 메커니즘을 보여줍니다

Research Article

Published on 2020-07-292022-08-13
Journal: PLoS ONE [Category] Biochemistry, COVID-19, MERS, SARS,

Smoking-Mediated Upregulation of the Androgen Pathway Leads to Increased SARS-CoV-2 Susceptibility

Article

Published on 2020-05-212022-10-29
Journal: International Journal of Molecular Sciences [Category] COVID-19, MERS,

An Extensive Meta-Metagenomic Search Identifies SARS-CoV-2-Homologous Sequences in Pangolin Lung Viromes

Observation

Published on 2020-05-062022-10-30
Journal: mSphere [Category] COVID-19, MERS, SARS,

Use of >100,000 NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium whole genome sequences improves imputation quality and detection of rare variant associations in admixed African and Hispanic/Latino populations

정밀 의학(TOPMed)을 위한 100,000개 이상의 NHLBI Trans-Omics 컨소시엄 전체 게놈 서열의 사용은 아프리카 및 히스패닉/라틴계 혼합 인구 집단에서 전가 품질 및 희귀 변이 연관성 검출 개선

Research Article

Published on 2019-12-232022-09-06
Journal: PLoS Genetics [Category] Communicable Disease,

[키워드] 1000 Genomes Project addition African allele Analysis Anemia approach association average blood cell complex complex diseases conducted demonstrated European Frequency genetic architecture Genetic studies genetic study genome coverage genome-wide association genome-wide genotyping genome-wide significant Genotype genotype data genotype imputation genotypes Haplotype Reference Consortium HBB HBB gene HCT hematocrit hematological hemoglobin highlight homozygous impair IMPROVE imputation increase in independent individual information Linkage disequilibrium low frequency MAF mapping Medicine minor allele frequency MOST NHLBI phase Population populations power Quantitative rare variant Rare variants reference panel replicated rescued sequence Sequencing sequencing data subsequent traits utility variant variants WBC White blood cell white blood cell count whole genome whole genome sequence Whole genome sequencing
[DOI] 10.1371/journal.pgen.1008500 PMC 바로가기 [Article Type] Research Article