Comparing outcomes of hospitalized patients with moderate and severe COVID-19 following treatment with hydroxychloroquine plus atazanavir/ritonavir하이드록시클로로퀸 + 아타자나비르/리토나비르 치료 후 중등도 및 중증 COVID-19로 입원한 환자의 결과 비교Comparative Study Published on 2020-12-012022-09-11 Journal: Daru : journal of Faculty of Pharmacy, Tehran Univ [Category] 치료제, [키워드] 28-day mortality Admission adverse events age Antiviral antiviral therapy Atazanavir atazanavir/ritonavir baseline Clinical outcome clinical outcomes Complication Course COVID-19 Definition discharge discharge rate discharged patient discharged patients disease Dyspnea Efficacy and safety evaluated exertional dyspnea Hair loss hospital Hospital admission hospital discharge Hospital stay Hospitalization hospitalized patient Hydroxychloroquine ICU incidence intensive care intensive care unit intubation investigated Length less male matter moderate Mortality National national treatment outcome outcomes oxygen Patient patients patients treated patients with COVID-19 patients with moderate peripheral oxygen saturation Pneumonia regimen Ritonavir Serious Adverse Event Serious Adverse Events severe COVID-19 severe disease severe group severity significantly higher significantly shorter SpO2 Support Symptom the disease the patient Treatment treatment of COVID-19 Treatment protocol use of hydroxychloroquine weakness WHO definition [DOI] 10.1007/s40199-020-00369-2 PMC 바로가기 [Article Type] Comparative Study
COVID-19 infection: epidemiological, clinical, and radiological expression among adult populationResearch Published on 2020-11-252022-10-31 Journal: The Egyptian Journal of Radiology and Nuclear Medicine [Category] COVID-19, [키워드] Admission age backbone Bilateral both group chest pain Computed tomography Coronavirus infection COVID-19 COVID-19 infection COVID-19 pandemic D-dimer D-dimer level Diagnosis diagnostic Dyspnea elevated epidemiological evaluated expression Fever Follow-up Gender GGOs Ground glass opacity Home isolation Hospitalization HRCT hypertension ICU Increasing intensive care Laboratory Lung fibrosis male negative correlation Non-severe case Outbreaks outcome oxygen saturation oxygen support Patient Pneumonia polymerase chain radiological Result risk factor RT-PCR sensitivity Serum ferritin Severe case Severe COVID-19 pneumonia severe group severity Significant smoking transcriptase Treatment troponin levels [DOI] 10.1186/s43055-020-00341-9 PMC 바로가기 [Article Type] Research
The potential role of serum angiotensin-converting enzyme in coronavirus disease 2019코로나바이러스 질병 2019에서 혈청 안지오텐신 전환 효소의 잠재적 역할Research Article Published on 2020-11-252022-09-10 Journal: BMC Infectious Diseases [Category] SARS, 바이오마커, [키워드] ACE activity analyzed angiotensin Angiotensin-converting enzyme baseline BMI body mass body mass index clinical condition Clinical data Clinical significance consecutive patient control group controls coronavirus disease Coronavirus disease 2019 COVID-19 demographic Demographic and clinical data hypertension lowest marker no significant difference no significant differences Older Patient patients proportion recruited Remission Result Retrospective study SARS-CoV-2 serum Serum ACE severe group Severe patient severity of COVID-19 subject the disease was measured were recorded [DOI] 10.1186/s12879-020-05619-x PMC 바로가기 [Article Type] Research Article
Factors associated with acute cardiac injury and their effects on mortality in patients with COVID-19급성 심장 손상과 관련된 요인 및 COVID-19 환자의 사망률에 미치는 영향Article Published on 2020-11-242022-09-10 Journal: Scientific Reports [Category] SARS, 바이오마커, [키워드] ACI Acute cardiac injury Analysis Biomarkers Brain brain natriuretic peptide C-reactive protein Cardiology Clinical characteristics collected Combination COVID-19 cumulative determine develop disease severity Effect elevated Elevation Factor Gender hs-CRP identify IL-6 in-hospital mortality in-patient incidence independent risk factor independent risk factors interleukin interleukin-6 Kaplan–Meier method Laboratory laboratory-confirmed Laboratory-confirmed COVID-19 Lactate lactate dehydrogenase Logistic regression male Mortality N-terminal NT-proBNP oxygen oxygen saturation Patient patients with COVID-19 peptide proportion radiological Risk factors sensitivity severe cases severe group Severe patient severe patients severity significantly higher significantly increased the disease Tongji Hospital Treatment was used were used Wuhan [DOI] 10.1038/s41598-020-77172-1 PMC 바로가기 [Article Type] Article
Assessing the Severity of Illness in Patients With Coronavirus Disease in Saudi Arabia: A Retrospective Descriptive Cross-Sectional StudyPublic Health Published on 2020-11-192022-10-31 Journal: Frontiers in Public Health [Category] COVID-19, MERS, SARS, [키워드] Abdul analyzed Assessing Aziz Characteristics chronic condition Clinical characteristics collected Comorbidities condition COVID-19 diabetes disease disorder distribution epidemiological groups hospital hypertension illness Infectious disease information Laboratory medical record medication MOST Non-severe non-severe cases outcome Patient patients patients with COVID-19 Prince remained reported Saudi Arabia severe severe disease severe group severe patients severity significantly higher Symptoms Thyroid variable [DOI] 10.3389/fpubh.2020.593256 PMC 바로가기 [Article Type] Public Health
The characteristics of cancerous patients infected with COVID-19 in hospital settingObservational Study Published on 2020-11-102022-10-04 Journal: Acta bio-medica : Atenei Parmensis [Category] 임상, [키워드] age C-reactive protein Cancer caused Characteristics Chemotherapy clinical feature Comorbidity correlated cough COVID-19 COVID-19 infection CRP declined demographic characteristics diarrhea elevated evaluated form group groups hospital hospitalized patient infected with COVID-19 Infection laboratory data malignancy Mild Mortality mortality rate myalgia pandemic Patient patients with COVID-19 positive reported risk severe group severity severity of COVID-19 significant effect significantly significantly higher significantly lower synchronous virus WBC white [DOI] 10.23750/abm.v91i4.10175 PMC 바로가기 [Article Type] Observational Study
Risk factors associated with disease aggravation among 126 hospitalized patients with COVID-19 in different places in China A retrospective observational study4900 Published on 2020-11-062022-10-30 Journal: Medicine [Category] COVID-19, SARS, [키워드] Admission age ALB albumin applied average C-reactive protein China clinical manifestation Coronavirus disease 2019 COVID-19 diarrhea disease Dyspnea exhibited Factor Factors hemoglobin hospitalized patient hypertension identify independent risk factor Intervention Laboratory test Logistic regression Logistic regression analysis Lymphocyte count neutrophil count Older Patient patients with COVID-19 potential risk Prevent procalcitonin proportion Protein recruited regression analysis retrospective Retrospective study risk factor Severe acute respiratory syndrome severe COVID-19 severe disease severe group severe type significantly Spread weakness with COVID-19 Wuhan [DOI] 10.1097/MD.0000000000022971 PMC 바로가기 [Article Type] 4900
The study of automatic machine learning base on radiomics of non-focus area in the first chest CT of different clinical types of COVID-19 pneumoniaArticle Published on 2020-11-032022-10-04 Journal: Scientific Reports [Category] 임상, 치료법, [키워드] Accuracy AUC can be used characteristic Chest CT Chest CT image Cohort collected control group COVID-19 evaluate feature greater Infectious diseases laboratory data lung moderate Negative predictive value NPV Outcomes research patients with COVID-19 Pneumonia positive PPV predict Predictive Respiratory tract diseases ROC selected severe group Severe patient statistical analysis the patient TNR TPR true negative were used with COVID-19 [DOI] 10.1038/s41598-020-76141-y PMC 바로가기 [Article Type] Article
Differences of inflammatory and non-inflammatory indicators in Coronavirus disease-19 (COVID-19) with different severity중증도가 다른 코로나바이러스감염증-19(COVID-19)의 염증성 지표와 비염증성 지표의 차이Observational Study Published on 2020-11-012022-08-31 Journal: Infection, genetics and evolution : journal of mol [Category] MERS, 바이오마커, 임상, [키워드] analyzed association C-reactive protein characteristic Characteristics clinical Clinical data collected community-acquired pneumonia Comorbidities Comorbidity Concentration coronavirus correlation COVID-19 COVID-19 severity Critical critical COVID-19 patient CRP D-dimer decrease difference Efficacy evaluate evaluated except for IL-6 indicated Inflammatory Inflammatory indicators initial interleukin interleukin-6 lymphocyte Lymphocyte count lymphocyte counts Lymphocytes neutrophil neutrophil count neutrophil counts Neutrophils Patient PCT peak concentration peak concentrations Pneumonia predict procalcitonin Prognosis receiver operating characteristic Result ROC ROC Curve ROC curves serum serum troponin severe COVID-19 severe group severity significant difference significant differences statistically significant the disease the patient troponin I two groups Variation variety were used [DOI] 10.1016/j.meegid.2020.104511 PMC 바로가기 [Article Type] Observational Study
Serum KL-6 level is a useful biomarker for evaluating the severity of coronavirus disease 2019혈청 KL-6 수준은 코로나바이러스 질병 2019의 중증도를 평가하는 데 유용한 바이오마커입니다Article Published on 2020-11-012022-08-31 Journal: Respiratory investigation [Category] MERS, 바이오마커, [키워드] Biomarker category center Characteristics Comorbidities coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 severity Critical cut-off cut-off value diagnosed with COVID-19 Diagnosis died disease disease severity elevated enrolled evaluate examined groups Infection Japanese Krebs von den Lungen-6 median Mild moderate non-severe group Older Patient peak level peak levels Pneumonia radiological receiver operating characteristic Red sensitivity serum severe COVID-19 severe group severe or critical illness severity severity of COVID-19 significantly significantly higher specificity to define two group two groups U/mL Viral viral infection was used were used worsened [DOI] 10.1016/j.resinv.2020.07.004 PMC 바로가기 [Article Type] Article