Retrospective analysis of COVID-19 among 391 hospitalized patients in the Henan province of China4400 Published on 2023-07-212024-09-05 Journal: Medicine [Category] update2024, [키워드] COVID-19 different sex old age Retrospective analysis severe group [DOI] 10.1097/MD.0000000000034325 PMC 바로가기 [Article Type] 4400
Reduced circulating FABP2 in patients with moderate to severe COVID-19 may indicate enterocyte functional change rather than cell deathArticle Published on 2022-11-052022-11-15 Journal: Scientific Reports [Category] SARS, 바이오마커, 진단, [키워드] acid Alter alteration Biomarker caused cell death change circulating Cohort contribute COVID-19 COVID-19 patient disease dysfunction Europe exclusion FABP2 functional Gut immune include increase in Infection Inflammation Inflammatory responses inhibited marker median metabolites microbial product Mild moderate NMR outliers pathology Patient patients with moderate plasma Plasma marker positive correlation reduced reduction in route of infection SARS-CoV-2 SARS-COV-2 infection severe COVID-19 severe disease severe group Severity of disease shown systemic [DOI] 10.1038/s41598-022-23282-x PMC 바로가기
Comparing the expression levels of tripartite motif containing 28 in mild and severe COVID-19 infectionArticle Published on 2022-10-032022-11-15 Journal: Virology Journal [Category] 치료제, [키워드] 25-hydroxyvitamin D age Analysis antiviral immune response association cholesterol control group coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 infection COVID-19 patients determine differential expression disease downregulation enrolled Epigenetic erythrocyte sedimentation rate ESR evaluated expression level HDL healthy control high-density in both group indicated Infection LDL low-density Mild mild infection motif mRNA level multivariate logistic regression Patient patients PCR cycle polymerase chain Proteins qPCR reduction in required Severe COVID-19 Infection severe group Severe infection severe infections severity severity of COVID-19 significantly lower the mean threshold TRIM28 Tripartite Motif Tripartite motif containing 28. was used [DOI] 10.1186/s12985-022-01885-0 PMC 바로가기
The role of electrolyte imbalances in predicting the severity of COVID-19 in the hospitalized patients: a cross-sectional study Research Published on 2022-08-302022-10-05 Journal: Scientific Reports [Category] SARS, 치료법, [키워드] age C-reactive protein Coronavirus disease 2019 COVID-19 Critical critical cases cross-sectional CRP cut-off D-dimer Electrolyte electrolyte imbalance examined ferritin Hospitalized hospitalized patient illness Inflammatory marker introduced lactate dehydrogenase LDH Lymphocyte count male median median value moderate parameter Patient patients Potassium predict Sensitivity and specificity severe cases severe group severity severity and prognosis severity of COVID-19 sodium suggested the disease three group were measured with COVID-19 [DOI] 10.1038/s41598-022-19264-8 [Article Type] Research
Plasma biomarkers of brain injury in COVID-19 patients with neurological symptoms신경계 증상이 있는 COVID-19 환자의 뇌 손상에 대한 혈장 바이오마커Article Published on 2022-08-152022-09-11 Journal: Journal of the neurological sciences [Category] MERS, 바이오마커, [키워드] Acidic acute phase Biomarker Biomarkers Blood Blood samples Brain brain injury Cohort cohort of patient Control correlation COVID-19 COVID-19 infection COVID-19 patient COVID-19 patients disease disease severity enrolled examined future work GFAp group healthy control immunoassay Injury Neurological symptom Neurological symptoms neuronal Patient patients plasma Plasma levels Prospective Study Protein reported S100B SARS-CoV-2 serum severe group significantly higher Symptom the disease were measured with COVID-19 [DOI] 10.1016/j.jns.2022.120324 PMC 바로가기 [Article Type] Article
Patterns of COVID-19-related headache: A cross-sectional studyResearch article Published on 2022-08-012022-10-05 Journal: Clinical neurology and neurosurgery [Category] COVID19(2023년), SARS, 임상, [키워드] acute infection age asymptomatic subjects Bilateral body mass index Characteristics Clinical severity COVID-19 cross-sectional demographic distribution enrolled headache healthcare worker Infection intensity investigated less mild cases moderate neuroinvasion neurological neurological manifestations Paracetamol Patient patients with COVID-19 pattern reported Result SARS-CoV-2 virus severe group Sex significantly higher significantly more Symptom Turkey were recorded [DOI] 10.1016/j.clineuro.2022.107339 [Article Type] Research article
Coagulation parameters abnormalities and their relation to clinical outcomes in hospitalized and severe COVID-19 patients: prospective study Research Published on 2022-08-012022-10-05 Journal: Scientific Reports [Category] 바이오마커, 임상, 치료법, [키워드] abnormality activated biochemical biochemical parameter clinical Clinical outcome Coagulation coagulation parameter Coagulation parameters Concentration COVID-19 COVID-19 patient COVID-19 severity cut-off D dimer D-dimer death diagnosed difference Dyspnea enrolled fibrinogen hematological Hospitalized inflammatory markers LDH non-severe group Older outcome parameter parameters Partial Patient patients Predictive Prospective Study prothrombin risk Sensitivity and specificity severe COVID-19 severe group Severe patient severity severity of COVID-19 survival the patient time were recorded [DOI] 10.1038/s41598-022-16915-8 [Article Type] Research
Association between smoking and COVID-19 severity: A multicentre retrospective observational studyObservational Study Published on 2022-07-222022-10-04 Journal: Medicine [Category] COVID19(2023년), SARS, 임상, [키워드] Accuracy active smoking Algorithms Analysis Clinical severity Comorbidities complex coronavirus disease COVID-19 COVID-19 severity decrease diabetes enrolled hospital hypertension Interaction Jiangsu multicentre non-severe group number of comorbidity Patient patients patients with COVID-19 predictor variable progression proportion Prospective Study random remained retrospective risk factor risk of COVID-19 selective severe COVID-19 severe disease severe group severity significant interaction significantly significantly higher smoking smoking status Univariate analysis were used [DOI] 10.1097/MD.0000000000029438 PMC 바로가기 [Article Type] Observational Study
Serum gasdermin D levels are associated with the chest computed tomography findings and severity of COVID-19Research article Published on 2022-07-012022-10-05 Journal: Respiratory investigation [Category] 바이오마커, 치료기술, [키워드] Affect Apoptosis apoptotic Area association Caspase-cleaved cytokeratin 18 fragment Chest computed tomography Chest CT clinical manifestation clinical status conducted consolidation COVID-19 Critical cross-sectional analysis diagnosed with COVID-19 died Excessive activation gasdermin D Ground glass opacity GSDMD immune response marker mechanical ventilation Mild moderate Patient patients with COVID-19 positively correlated programmed cell death pyroptosis required Result serum severe group severity of COVID-19 the disease three group [DOI] 10.1016/j.resinv.2022.06.007 [Article Type] Research article
Association of epicardial adipose tissue with the severity and adverse clinical outcomes of COVID-19: A meta-analysisReview article Published on 2022-07-012022-10-05 Journal: International Journal of Infectious Diseases [Category] 바이오마커, 임상, [키워드] 95% confidence interval adipose Adiposity Adverse adverse outcome chronic obstructive CIs Clinical outcome Computed tomography Control Coronary artery disease COVID-19 COVID-19 severity database diabetes Effect Epicardial adipose tissue help Hospitalization independent intensive care Invasive mechanical ventilation mean difference measure Meta-analysis objective Patient patients with COVID-19 poor prognosis positive primary end point Prognosis prognostic risk stratification pulmonary disease Quantitative Result risk factor Risk factors searched severe group severity SMD tissue visceral [DOI] 10.1016/j.ijid.2022.04.013 [Article Type] Review article