Public Health and Risk Communication During COVID-19—Enhancing Psychological Needs to Promote Sustainable Behavior ChangePublic Health Published on 2020-10-272022-10-31 Journal: Frontiers in Public Health [Category] COVID-19, MERS, SARS, [키워드] Anxiety applied approach Behavior behavior change Care change communication coronavirus COVID-19 COVID-19 pandemic Depression distress effective ENhance FIVE Guidance Health health communication (MESH) human behavior infodemic information Interaction mental health disorders mitigate pandemic Pandemics promote psychological need Public public health public health communication recommendation Research risk Risk communication searched starting point Support theory virus Well-being [DOI] 10.3389/fpubh.2020.573397 PMC 바로가기 [Article Type] Public Health
De novo design of picomolar SARS-CoV-2 miniprotein inhibitorsResearch Article Published on 2020-10-232022-10-28 Journal: Science (New York, N.y.) [Category] COVID-19, MERS, SARS, [키워드] ACE2 acute respiratory syndrome affinity amino acid sequence angiotensin-converting enzyme 2 antibodies approaches binding binding modes blocked Cell complex coronavirus de novo docked ectodomain expression high affinity high stability Host host cell receptor human Angiotensin-converting enzyme identify inhibitor inhibitory concentration initiated interact Interaction mammalian mammalian cells median Microscopy miniprotein monoclonal antibody nasal Prevent Protein RBD receptor Receptor binding domain Respiratory system SARS-CoV-2 SARS-COV-2 infection Science spike Spike protein Spike proteins spikes stability starting point Structure targeting the RBD the SARS-CoV-2 therapeutic strategy therapy trimer Vero E6 cell VERO E6 cells viral entry [DOI] 10.1126/science.abd9909 PMC 바로가기 [Article Type] Research Article
Structure‐Activity Relationships of Benzamides and Isoindolines Designed as SARS‐CoV Protease Inhibitors Effective against SARS‐CoV‐2Full Paper Published on 2020-10-162022-10-31 Journal: ChemMedChem [Category] COVID-19, SARS, [키워드] acute respiratory syndrome antiviral activity Antiviral agents Benzamide binding mode Cell culture Computational chemistry coronavirus CoV cysteine protease cytotoxicity drug design highlight homologous Infection inhibit inhibition inhibitor inhibitors Isoindoline Pathogens protease protease inhibitors relationship Replication SAR SARS‐CoV‐2 shown similarity starting point Structure-activity relationships target proteases treat [DOI] 10.1002/cmdc.202000548 PMC 바로가기 [Article Type] Full Paper
New Frontiers for Selective Biosensing with Biomembrane-Based Organic TransistorsPerspective Published on 2020-10-142022-10-27 Journal: ACS Nano [Category] COVID-19, [키워드] artificial membrane biological system detect Disease diagnosis Drug screening healthcare highlighting IMPROVE lack new frontier organic platform provide sensitivity starting point transistor vital role [DOI] 10.1021/acsnano.0c07053 PMC 바로가기 [Article Type] Perspective
Crystallographic and electrophilic fragment screening of the SARS-CoV-2 main proteaseArticle Published on 2020-10-072022-10-04 Journal: Nature Communications [Category] SARS, 변종, 신약개발, 치료제, [키워드] antiviral drug approach caused coronavirus COVID-19 COVID-19 therapeutics cysteine develop drug design effective electrophilic Enzymes identify information inhibitor lack mass spectrometry MERS-CoV offer Outbreaks performed progressed protease Proteases reactivity SARS-CoV-1 SARS-CoV-2 SARS-CoV-2 main protease starting point Structure the SARS-CoV-2 Vaccine Viral protein viral replication X-ray X-ray crystallography zoonotic [DOI] 10.1038/s41467-020-18709-w PMC 바로가기 [Article Type] Article
Many small steps towards a COVID-19 drugComment Published on 2020-10-072022-10-29 Journal: Nature Communications [Category] COVID-19, MERS, SARS, [키워드] COVID-19 crystal structure Drug discovery global research community protease SARS-CoV-2 starting point structural biology [DOI] 10.1038/s41467-020-18710-3 PMC 바로가기 [Article Type] Comment
Deep phenotyping of 34,128 adult patients hospitalised with COVID-19 in an international network studyArticle Published on 2020-10-062022-10-04 Journal: Nature Communications [Category] MERS, 치료법, [키워드] aggregate Characteristics Comorbidity condition coronavirus disease country COVID-19 COVID-19 patient COVID-19 patients database deep Epidemiology estimate female group help hospitalised include individual Influenza International knowledge majority male medication Patient patients Prevalence profile public health Risk factors SARS-CoV-2 Seven South South Korea Spain starting point unique viral epidemiology while with COVID-19 [DOI] 10.1038/s41467-020-18849-z PMC 바로가기 [Article Type] Article
A comparative study of international and Chinese public health emergency management from the perspective of knowledge domains mappingResearch Article Published on 2020-10-022022-10-31 Journal: Environmental health and preventive medicine [Category] Coronavirus, MERS, SARS, [키워드] acute respiratory syndrome Analysis article China Chinese collected coronavirus disease country COVID-19 damaged database Developed Diseases distribution distribution analysis domain Emergency management Epidemics European country events handling Health health emergency Infrastructure International knowledge Knowledge domains management mechanism network analysis organizations outbreak Perspective producing public health public health emergency Research Result starting point Web of Science were used World Health Organization [DOI] 10.1186/s12199-020-00896-z PMC 바로가기 [Article Type] Research Article
Phytochemicals containing biologically active polyphenols as an effective agent against Covid-19-inducing coronavirusReview article Published on 2020-10-012022-10-05 Journal: Journal of Functional Foods [Category] 치료제, [키워드] Antiviral antiviral therapy benefit Bioactivity caused Compound coronavirus disease drug effective Enzymes Infection inhibit inhibiting knowledge lack Luteolin medicament outbreak pandemic Patient phytochemical phytochemicals plant extracts polyphenols Proteases Research Side effects starting point Structure Treatment Vaccines virus replication [DOI] 10.1016/j.jff.2020.104146 [Article Type] Review article
Ten simple rules for supporting a temporary online pivot in higher educationEditorial Published on 2020-10-012022-10-28 Journal: PLoS Computational Biology [Category] Coronavirus, MERS, SARS, [키워드] cohorts Course COVID-19 facilitate globe include practicality provide question starting point [DOI] 10.1371/journal.pcbi.1008242 PMC 바로가기 [Article Type] Editorial