Deep Sequencing of B Cell Receptor Repertoires From COVID-19 Patients Reveals Strong Convergent Immune SignaturesCOVID-19 환자의 B 세포 수용체 레퍼토리의 심층 시퀀싱으로 강력한 수렴 면역 신호가 나타남Immunology Published on 2020-12-152022-09-12 Journal: Frontiers in Immunology [Category] MERS, SARS, 진단, [키워드] antibody association B cell B-cell repertoire BCR bystander China clonal expansion Cohort convergence COVID-19 COVID-19 patient COVID-19 patients data set deep demonstrated Effects healthy control heavy chain help homologous identify immune response individual memory Neutralizing antibodies Patient patients prophylactic antibody receptor repertoire resource responses reveal SARS-CoV-2 SARS-CoV-2 spike protein Seasonal influenza sequence Sequencing signature Strong subset the disease therapeutic USA vaccination [DOI] 10.3389/fimmu.2020.605170 PMC 바로가기 [Article Type] Immunology
Negative Clinical Evolution in COVID-19 Patients Is Frequently Accompanied With an Increased Proportion of Undifferentiated Th Cells and a Strong Underrepresentation of the Th1 SubsetImmunology Published on 2020-11-262022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, MERS, SARS, [키워드] Activation Adaptive immune response affected Analysis Blood CD38 CD4+ CD8 CD8+ CD8+ T cell Cell characterized clinical COVID-19 COVID-19 patient Critical decrease donors effective explain Express Factor Frequency Frequently high-risk population HLA-DR immune profiling Increased Inflammatory innate response lymphocyte lymphopenia marker multiparametric flow cytometry negative outcome Patient performed Peripheral blood SARS-COV-2 infection severe acute respiratory syndrome coronavirus 2 severe coronavirus disease 2019 severity Strong subset T cell T cell response T cells T cells response T helper T lymphocyte T-CD8 lymphocytes flow cytometric immunophenotyping Th cell Th lymphocytes Th1 Th1 cell Th1/Th17 Th17 Undifferentiated virus infection virus load [DOI] 10.3389/fimmu.2020.596553 PMC 바로가기 [Article Type] Immunology
Ensuring that COVID-19 research is inclusive: guidance from the NIHR INCLUDE projectResearch Methods Published on 2020-11-052022-10-28 Journal: BMJ Open [Category] COVID-19, Fulltext, SARS, [키워드] affected Analysis Asian benefit black Care Characteristics collected Community comparison COVID-19 COVID-19 research criteria dissemination early stage engage Ensuring Evidence flexible group groups Guidance include Intervention Local multiple long-term conditions NIHR obesity objective Older outcome public health Research Research question researchers statistics & research methods Strong These data Topic Trial [DOI] 10.1136/bmjopen-2020-043634 PMC 바로가기 [Article Type] Research Methods
Consideration of the Psychological and Mental Health of the Elderly during COVID-19: A Theoretical ReviewReview Published on 2020-11-032022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, SARS, [키워드] age confirmed case COVID-19 death effective elderly facilitate Factors group groups Health identify measure Mental mental health occur occurred pandemic physical physical activity Prevent PROTECT protective factor Protective factors Psychological public health crisis quarantine raised review Safe Self-efficacy social distancing Spread Stress Strong Support tested Treatment World Health Organization [DOI] 10.3390/ijerph17218098 PMC 바로가기 [Article Type] Review
Epidemiology, evolutionary origin, and malaria‐induced positive selection effects of G6PD ‐deficient alleles in Chinese populations중국 인구에서 G6PD 결핍 대립유전자의 역학, 진화 기원 및 말라리아 유발 양성 선택 효과Original Article Published on 2020-10-312022-10-30 Journal: Molecular Genetics & Genomic Medicine [Category] COVID-19, 말라리아, [키워드] affected allele Analysis Bioinformatic China Chinese Chinese population correlated deficiency disorder Effect Epidemiology Evidence evolutionary origin Features FIVE Frequency G6PD Genome glucose‐6‐phosphate dehydrogenase (G6PD) information malaria natural selection nucleotide pathogenic performed Population populations Positive selection Prevalence ranged reported Result Strong variant [DOI] 10.1002/mgg3.1540 PMC 바로가기 [Article Type] Original Article
Information about COVID-19 among Selected Population of Eastern Nepal: A Descriptive Cross-sectional StudyOriginal Article Published on 2020-10-312022-10-30 Journal: JNMA: Journal of the Nepal Medical Association [Category] COVID-19, MERS, SARS, [키워드] eastern Nepal information calculated clearance collected conducted confidence coronavirus Course COVID-19 cross-sectional ethical review board Frequency Health help information interval knowledge media Nepal Participants Point Population preventive measure preventive measures professionals proportion questionnaire Rapid selected service Spread spread of COVID-19 Statistical Package Strong the disease was done was used website WHO [DOI] 10.31729/jnma.5096 PMC 바로가기 [Article Type] Original Article
Investigating the Prevalence of Reactive Online Searching in the COVID-19 Pandemic: Infoveillance StudyOriginal Paper Published on 2020-10-272022-10-30 Journal: Journal of Medical Internet Research [Category] COVID-19, MERS, SARS, [키워드] addressed affected age being Care carried Chloroquine circulation coronavirus correlation Correlation analysis country COVID-19 COVID-19 pandemic COVID-19 testing death determine disease dissemination European fake news Germany global pandemic Google Google Trends Government Health ibuprofen identify imperative infodemiology information Italy limit maintain media misinformation Mortality mortality data objective pandemic Pandemics Panic portal positive correlation powerful tool Premature Public public health authorities resources Result resulting searched selected Spain Spearman Spread Strong temporal dynamics The United States trend United Kingdom Volume [DOI] 10.2196/19791 PMC 바로가기 [Article Type] Original Paper
The outcome of COVID-19 among the geriatric age group in African countries: protocol for a systematic review and meta-analysisResearch Published on 2020-10-082022-10-28 Journal: Asthma Research and Practice [Category] COVID-19, [키워드] Africa African age Analysis conducted coronavirus disease COVID-19 database Egger’s test Evidence expected funnel plots geriatric Google Google Scholar heterogeneity independent Index Medicus library Meta-analysis outbreak outcome pandemic proportion Prospective protocol public health emergency random-effects model reported review Risk of bias searched Strong submitted systematic review Web of Science WHO World Health Organization [DOI] 10.1186/s40733-020-00064-8 PMC 바로가기 [Article Type] Research
Increase in prevalence of current mental disorders in the context of COVID-19: analysis of repeated nationwide cross-sectional surveysOriginal Article Published on 2020-09-292022-11-01 Journal: Epidemiology and Psychiatric Sciences [Category] COVID-19, SARS, [키워드] 95% CI addition alcohol analysed Analysis Anxiety Anxiety Disorder anxiety disorders association baseline baseline analysis calculated consequence COVID-19 COVID-19 pandemic cross-sectional survey Depression depressive diagnostic disorder Evidence females Health increase increase in interview lack lockdown Logistic regression Mental Mental disorder Mental Disorders mental health mental health problem MINI populations Prevalence provide repeated Result risk SARS-CoV-2 significant increase Strong suicide risk Symptom United Nation [DOI] 10.1017/S2045796020000888 PMC 바로가기 [Article Type] Original Article
Recommendations for detection, prioritization, and treatment of thoracic oncology patients during the COVID‐19 pandemic: the THOCOoP cooperative groupReview article Published on 2020-09-012022-10-05 Journal: Critical Reviews in Oncology/Hematology [Category] SARS, 치료기술, [키워드] Cancer Care Consensus country COVID-19 COVID‐19 deleted DelPhi Evidence health systems higher risk information initial lung cancer lung cancer patient lung cancer patients maintain oncology oncology patient outcome pandemic Personal protective equipment question reached recommendation recommendations SARS-CoV-2 Strong Thoracic Thoracic oncology Treatment [DOI] 10.1016/j.critrevonc.2020.103033 [Article Type] Review article