Interferon Induction by RNA Viruses and Antagonism by Viral PathogensReview Published on 2014-12-122023-08-29 Journal: Viruses [Category] E형 간염, [키워드] interferon induction RLR TLR viral antagonism [DOI] 10.3390/v6124999 PMC 바로가기 [Article Type] Review
Toll-like receptor-based adjuvants: enhancing the immune response to vaccines against infectious diseases of chicken톨 유사 수용체 기반 보조제: 감염성 질병에 대한 백신에 대한 면역 반응 강화Review Published on 2014-07-012023-06-02 Journal: Expert review of vaccines [Category] 살모넬라증, 조류인플루엔자, [키워드] adjuvants agonist chicken cytokine Infectious disease poultry TLR Vaccine [DOI] 10.1586/14760584.2014.920236 [Article Type] Review
Regulation of macrophage and dendritic cell function by pathogens and through immunomodulation in the avian mucosaReview Published on 2013-11-012023-06-02 Journal: Developmental and comparative immunology [Category] 조류인플루엔자, [키워드] (Draining) lymph nodes Ag AIV Antigen antigen-presenting cells APC Avian influenza virus BALT BM Bone marrow bronchus-associated lymphoid tissue C-type lectin receptors CG chicken galectin chicken lung lectin CLL CLR DC DC-SIGN DC-specific intercellular adhesion molecule-3-grabbing non-integrin dendritic cells DLN GALT gut-associated lymphoid tissue HA Haemagglutinin highly-pathogenic avian influenza HPAI IAV IBDV IBV immunomodulation Infection Infectious Bronchitis Virus infectious bursal diease virus influenza A virus laboratory of genetics and physiology 2 LGP2 lipopolysaccharide Low pathogenic influenza LPAI LPS macrophage galactose binding lectin macrophage mannose receptor macrophages MDA5 Melanoma differentiation-associated protein 5 MGL MMR MPh mucosal NA NALT nasal associated lymphoid tissue NDV neuraminidase newcastle disease virus Pattern recognition receptors PRR respiratory tract retinoic acid-inducible gene I RIG-I Rt TLR Toll-like receptors [DOI] 10.1016/j.dci.2013.03.008 [Article Type] Review
Proteolytic activity of Plasmodium falciparum subtilisin-like protease 3 on parasite profilin, a multifunctional proteinarticle Published on 2013-10-312024-09-01 Journal: Molecular and Biochemical Parasitology [Category] 말라리아, [키워드] FITC fluoresceine isothiocyanate IL-12 interleukin 12 malaria Plasmodium falciparum profilin SD Subtilisin-like protease synthetic defined TLR TNF-α Toll-like receptor tumor necrosis factor-alpha [Article Type] article
Toll-like receptor sensing of human herpesvirus infectionarticle Published on 2012-10-082024-09-02 Journal: Frontiers in Cellular and Infection Microbiology [Category] 대상포진, [키워드] Cytokines herpesvirus Innate immunity interferons TLR [DOI] 10.3389/fcimb.2012.00122 PMC 바로가기 [Article Type] article
Protective Role of Toll-like Receptor 3-Induced Type I Interferon in Murine Coronavirus Infection of MacrophagesArticle Published on 2012-05-242022-10-28 Journal: Viruses [Category] Coronavirus, MERS, [키워드] Activation adaptive antigen-presenting cell antiviral immunity antiviral state chemokines chronic infection coronavirus CoV CoVs Cytokines diminishe Express IFN-β IFNs Immunity induce infancy infect Infection investigation Ligand Macrophage macrophage cell line macrophages MHV MHV-A59 mouse hepatitis virus murine murine coronavirus not affect pattern recognition receptor Poly I:C positive-sense PRR PRRs RNA virus role selected single-stranded Stimulation suppresse susceptibility TLR TLR2 TLR3 TLR4 TLR7 TLRs triggering Type Type I IFN type I interferon viral infection viral infections virus production viruses [DOI] 10.3390/v4050901 PMC 바로가기 [Article Type] Article
MyD88 Is Required for Protection from Lethal Infection with a Mouse-Adapted SARS-CoVResearch Article Published on 2008-12-122022-10-29 Journal: PLoS Pathogens [Category] Coronavirus, MERS, [키워드] 2003 absence adapter addition animal model antiviral therapies Atypical Author BALB/c mice C57BL/6 caused Cell characterized chemokine Chemokine receptor chest X-ray China circulating Clinical course compared contribute coronavirus correlated Course CoV death disease disease pathogenesis early response exhibited expression Factor function Genetic greater Host host gene Host immune response humans identify immune immune system Infection Inflammatory Inflammatory response innate immune intranasal Laboratory lethal Lower respiratory tract lung Lung inflammation lung tissue Lungs mice monocyte monocytes/macrophage Mortality mouse-adapted SARS-CoV Pneumonia Post-infection Proinflammatory cytokine protection Protein provide Pulmonary pathology receptor recruitment Replication required respiratory virus respond SARS-CoV SARS-CoV infection severe lung pathology Signaling significantly higher Spread susceptible TLR Travel Viral load viral loads viral replication virus wild-type [DOI] 10.1371/journal.ppat.1000240 PMC 바로가기 [Article Type] Research Article
Cytokine regulation in SARS coronavirus infection compared to other respiratory virus infections †Research Article Published on 2006-02-152022-11-01 Journal: Journal of medical virology [Category] Coronavirus, Fulltext, MERS, [키워드] acute respiratory syndrome Caco2 cell compared contribute cytokine Cytokine dysregulation cytokine profile cytokine signaling dysregulation human parainfluenza virus IFN IL‐6 IL‐6 immunopathology Inc induction Infection Inflammation Inflammatory cytokine Inflammatory response influenza A virus mechanism other respiratory virus Pathogenesis RANTES receptor Regulation Replication respiratory syncytial virus Respiratory virus infection RSV SARS Coronavirus SARS‐CoV significantly lower SOCS3 suggested suppressed TLR upregulated [DOI] 10.1002/jmv.20556 PMC 바로가기 [Article Type] Research Article