Technical performance of a lateral flow immunoassay for detection of anti-SARS-CoV-2 IgG in the outpatient follow-up of non-severe cases and at different times after vaccination: comparison with enzyme and chemiluminescent immunoassays중증이 아닌 환자의 외래 추적 관찰 및 백신 접종 후 다양한 시점에서 항-SARS-CoV-2 IgG 검출을 위한 측면 유동 면역분석의 기술적 성능: 효소 및 화학발광 면역분석과의 비교Article Published on 2022-07-132022-09-12 Journal: Revista do Instituto de Medicina Tropical de São [Category] MERS, 진단, [키워드] acute phase Analysis analyzed anti-SARS-CoV-2 IgG anti-SARS-CoV-2 IgG antibody antibody production Blood booster dose chemiluminescent immunoassay children chose CLIA collected composed Coronavirus infections COVID-19 decrease diagnosed donors Efficiency eight enzyme expected Finger prick Follow-up healthcare healthy immunoassay immunochromatographic assay Infection lateral flow lateral flow immunoassay LFIA likelihood ratio Non-severe case NPV operator participant Pediatric patient performed positive PPV produced RT-PCR sensitivity serological Serological assay serum sample serum samples Seven specificity study group tested the antibody the vaccine three group true negative vaccination Variation volunteers Whole blood [DOI] 10.1590/S1678-9946202264049 PMC 바로가기 [Article Type] Article
Urban monitoring, evaluation and application of COVID-19 listed vaccine effectiveness: a health code blockchain studyCOVID-19 등재 백신 효과의 도시 모니터링, 평가 및 적용: 건강 코드 블록체인 연구Article Published on 2022-07-132022-09-11 Journal: BMJ Open [Category] 변종, [키워드] aggravate Algorithm analysed Analysis Asymptomatic average basic reproduction number calculate city Complete conditions Contact cooperation country COVID-19 decrease deviation Effectiveness eight ENhance epidemiological Epidemiological investigation Epidemiology evaluate greater Health Health policy herd immunity Immunity increase Incubation period index infection rate information measure MONITOR mutant virus not decreased outcome Patient Primary outcome Primary outcomes promote promoted proportion protective effect reduced regions respond second significantly Simulation statistical symptomatic the vaccine this system transmitted urban urban population vaccination vaccination rate Vaccination strategy Vaccine Vaccines variant Variation virus weight [DOI] 10.1136/bmjopen-2021-057281 PMC 바로가기 [Article Type] Article
A Novel Deep Learning and Ensemble Learning Mechanism for Delta-Type COVID-19 Detection델타형 COVID-19 탐지를 위한 새로운 딥 러닝 및 앙상블 학습 메커니즘Article Published on 2022-07-082022-09-11 Journal: Frontiers in Public Health [Category] COVID19(2023년), SARS, 치료기술, 치료제, [키워드] Accuracy acute respiratory syndrome acute respiratory syndrome coronavirus AI Analysis applicability assumed AUC bottleneck chest X-ray Community Confusion confusion matrix coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 infection deep deep learning defined Delta-type COVID-19 detection diagnosing Diagnosis disease domain dry cough Dyspnea Ensemble learning ensemble learning technique f-score fatigue Features Fever hybrid deep learning. learning morbidity mortalities Mortality Non-invasive novel Novel coronavirus novel coronavirus disease ocular Other Patient Performance metrics Practitioner practitioners Precision presenting Radiographic radiologist recorded Research response SARS-CoV-2 Support support vector machine SVM Variation VGG16 virus X-ray [DOI] 10.3389/fpubh.2022.875971 PMC 바로가기 [Article Type] Article
Vaccination and variants: Retrospective model for the evolution of Covid-19 in Italy예방 접종 및 변종: 이탈리아의 Covid-19 진화에 대한 회고 모델Article Published on 2022-07-082022-09-11 Journal: PLoS ONE [Category] COVID19(2023년), SARS, 변종, [키워드] absence appearance changes characterized combined effect compartmental model contagious COVID-19 pandemic deaths decreases delta variant develop dominant effective Effects epidemiological Evolution followed by individual induce Infection Italy measure mechanism mechanisms normality omicron Omicron variant pandemic Particular predict Retrospective analysis seasonal variation stability vaccination Vaccine Variability variant Variation virus virus infectivity waning immunity [DOI] 10.1371/journal.pone.0265159 PMC 바로가기 [Article Type] Article
Genetic polymorphisms associated with susceptibility to COVID-19 disease and severity: A systematic review and meta-analysisCOVID-19 질병 및 중증도에 대한 감수성과 관련된 유전적 다형성: 체계적인 검토 및 메타 분석Meta-Analysis Published on 2022-07-062022-09-11 Journal: PLoS ONE [Category] 변종, [키워드] 95% CI ACE1 advanced age allele alleles analyzed ApoE article association C allele calculated candidate gene CCR5 clinical symptom Clinical symptoms Comorbidities contribute COVID-19 COVID-19 disease COVID-19 infection COVID-19 pathogenesis COVID-19 severity disease eligible fixed form forms Genetic polymorphism genetic polymorphisms Genetic variant genetic variants GWAS HLA HLA-A HLA-B HLA-C identify investigated involved loci Meta-analysis polymorphism Polymorphisms presence of comorbidity random Repository risk searched severe forms of COVID-19 severity of COVID-19 significantly Stata software suggested susceptibility systematic review the disease TMPRSS2 Variation [DOI] 10.1371/journal.pone.0270627 PMC 바로가기 [Article Type] Meta-Analysis
The clinically relevant CYP2C8*3 and CYP2C9*2 haplotype is inherited from Neandertals Research Published on 2022-07-022022-10-05 Journal: The Pharmacogenomics Journal [Category] 유전자 메커니즘, [키워드] alleles chromosome 10 clinically compounds CYP2C8 CYP2C9 cytochrome P450 enzyme drug drugs exhibit genes encoding Haplotype influence Linkage disequilibrium locus metabolism reduced therapeutic doses Toxicity Variation [DOI] 10.1038/s41397-022-00284-6 [Article Type] Research
Clinical-epidemiological variation in patients treated in the first and second wave of COVID-19 in Lambayeque, Peru: A cluster analysisResearch article Published on 2022-07-012022-10-05 Journal: International Journal of Infectious Diseases [Category] 임상, [키워드] Ageusia Analysis Anosmia applied Asymptomatic Care characteristic Characteristics characteristics of patient characterized Cluster cluster analysis Clustering Comorbidity conducted Coronavirus infection COVID-19 COVID-19 group COVID-19 pandemic cross-sectional diabetes Dyspnea enrolled Epidemiologic surveillance female Health identify less obesity objective Older pandemic pandemic wave participant Patient patients treated Peru pregnant respiratory Result second wave severe patients Symptom Symptoms systemic symptoms Variation [DOI] 10.1016/j.ijid.2022.07.045 [Article Type] Research article
Genetic variation of Golgi membrane protein 1 is associated with COVID-19 diseaseCorrespondence Published on 2022-07-012022-10-05 Journal: The Journal of Infection [Category] 바이오마커, 유전자 메커니즘, [키워드] disease Golgi membrane protein Variation with COVID-19 [DOI] 10.1016/j.jinf.2022.07.013 [Article Type] Correspondence
Receptor binding domain of SARS-CoV-2 from Wuhan strain to Omicron B.1.1.529 attributes increased affinity to variable structures of human ACE2우한 균주에서 Omicron B.1.1.529까지의 SARS-CoV-2 수용체 결합 도메인은 인간 ACE2의 가변 구조에 대한 증가된 친화성을 특성으로 합니다.Article Published on 2022-07-012022-09-11 Journal: Journal of infection and public health [Category] COVID19(2023년), MERS, SARS, 변종, 진단, 치료기술, [키워드] ACE2 ACE2 receptor ACE2 receptors ACE2 variant ACE2 variants ACE2-RBD affinity analysed Analysis angiotensin Angiotensin-converting enzyme attribute B.1.1.529 binding binding domain binding efficiency binding energy Care caused changes in coding region complexes contributing to COVID-19 detect determine docking dynamic Dynamic simulation enzyme Genetic variant genetic variants global pandemic help highlight homology model Homology models Human human ACE2 human host Infectious disease Interaction isolates lead management molecular molecular dynamics nucleotide omicron pathogenic polymorphism Protein docking RBD RBD complex RBDs receptor Receptor binding domain Repository retrieved risk RMSD RMSF Safe SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 genomes SARS-COV-2 infection SARS-CoV-2 strain SARS-CoV-2 virus SARS‐CoV‐2 selected severity single nucleotide stability Structural variant structural variants Structure the RBD Total variant Variation was performed wildtype Wuhan Wuhan strain [DOI] 10.1016/j.jiph.2022.06.004 PMC 바로가기 [Article Type] Article
Identification of phytocompounds as newer antiviral drugs against COVID-19 through molecular docking and simulation based study분자 도킹 및 시뮬레이션 기반 연구를 통한 COVID-19에 대한 새로운 항바이러스 약물로서의 식물 화합물 식별Article Published on 2022-07-012022-09-11 Journal: Journal of molecular graphics & modelling [Category] 변종, 치료제, [키워드] ADMET analysis Analysis antiviral activity antiviral drug antiviral drugs binding affinity complex conformational contagious COVID-19 docking docking score flexibility free energy free energy landscape identification in silico molecular docking molecular dynamic simulation molecular interaction pandemic Phytocompounds. promoted protease reflected screened selected Spike protein stability target protein target proteins variant Variation Viral protein Viral proteins Virtual screening virus was performed was used [DOI] 10.1016/j.jmgm.2022.108192 PMC 바로가기 [Article Type] Article