Beyond COVID-19: DO MS/NMO-SD patients treated with anti-CD20 therapies develop SARS-CoV2 antibodies?COVID-19 너머: 항-CD20 요법으로 치료받은 MS/NMO-SD 환자에게 SARS-CoV2 항체가 발생합니까?Article Published on 2020-11-012022-08-31 Journal: Multiple sclerosis and related disorders [Category] SARS, 바이오마커, [키워드] agent anti-CD20 anti-CD20 therapy consequence coronavirus Coronavirus infection COVID-19 COVID-19 infection develop disorder immune response immunosuppressants Infection Multiple multiple sclerosis Neuromyelitis Optica New coronavirus Patient patients treated Precaution Prevent risk of COVID-19 SARS-CoV-2 SARS-CoV2 serology Spread treated [DOI] 10.1016/j.msard.2020.102482 PMC 바로가기 [Article Type] Article
Coagulation biomarkers are independent predictors of increased oxygen requirements in COVID-19응고 바이오마커는 COVID-19에서 증가된 산소 요구량에 대한 독립적인 예측자입니다.Article Published on 2020-11-012022-09-11 Journal: Journal of thrombosis and haemostasis : JTH [Category] 바이오마커, [키워드] 95% CI 95% confidence interval activated Admission adult COVID-19 patient adverse outcome adverse outcomes age Analysis Antigen association baseline Biomarker Biomarkers BMI body mass body mass index C-reactive protein Coagulation Comorbidity confounder contribute COVID-19 COVID-19 patients CRP D-dimer D-dimers death diabetes factor VIII fibrinogen Follow-up FVIII hazard ratio hypercoagulability hypertension independent predictor leucocytes metabolic syndrome outcomes oxygen Oxygen requirement Oxygen requirements partial thromboplastin time Pathogenesis plasma Platelet platelet-poor plasma Platelets Pneumonia Predictive Prothrombin time regression analysis risk SARS-CoV-2 pneumonia SARS-CoV2 Sex significantly subdistribution syndrome THROMBOPLASTIN thrombosis univariable von Willebrand factor vWF [DOI] 10.1111/jth.15067 PMC 바로가기 [Article Type] Article
SARS-CoV2 envelope protein: non-synonymous mutations and its consequencesSARS-CoV2 외피 단백질: 동의어가 아닌 돌연변이와 그 결과Article Published on 2020-11-012022-09-11 Journal: Genomics [Category] SARS, 변종, [키워드] Affect analyzed Asia binding C-terminus Complete consequence COVID-19 domain envelope envelope protein Europe Genome genome sequence Genome sequences Guangzhou host protein Missense mutation Missense mutations motif NCBI database Non-synonymous mutation Non-synonymous mutations Oceania PALS1 Protein SARS-CoV2 SARS-CoV2 genomes transmembrane USA Victoria [DOI] 10.1016/j.ygeno.2020.07.001 PMC 바로가기 [Article Type] Article
COVID-19: Pharmacology and kinetics of viral clearanceCOVID-19: 바이러스 제거의 약리학 및 동역학Review Published on 2020-11-012022-09-11 Journal: Pharmacological research [Category] SARS, 치료제, [키워드] acute respiratory distress acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 biochemical caused Characteristics clearance clinical outcomes coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 death Efficacy evaluate Evidence evidence of feature focus form heterogeneity host immune system Italy large cohort Mild pandemic disease patients patients hospitalized persistence Pharmacology randomised controlled trial Randomised controlled trials respiratory respiratory distress SARS-CoV-2 SARS-CoV2 severe acute respiratory syndrome Coronavirus therapy Trial university Viral viral clearance Viral clearance kinetics. virus [DOI] 10.1016/j.phrs.2020.105114 PMC 바로가기 [Article Type] Review
Hyperthrombotic Milieu in COVID-19 PatientsReview Published on 2020-10-312022-10-31 Journal: Cells [Category] COVID-19, MERS, SARS, [키워드] alteration cascade clinically Coagulation coagulation cascade Coagulopathy component coronary syndrome coronavirus COVID-19 COVID-19 infection develop dominant Embolism endothelial cell damage endothelial damage endotheliopathy events Evidence experience extrinsic fibrinolytic implication Kidney failure marker mechanism Microvascular thrombosis milieu Mortality Multisystem organ failure Myocardial infarction nuance Occurrence Outbreaks parameter patients patients with COVID-19 predictor probe Respiratory failure risk SARS-CoV-2 SARS-COV-2 infection SARS-CoV2 shown stroke strokes systemic anticoagulation systemic manifestations the patient therapeutic targets therapy Thromboembolic event Thromboprophylaxis thrombosis triggered venous venous thromboembolic VTE while widespread with COVID-19 [DOI] 10.3390/cells9112392 PMC 바로가기 [Article Type] Review
Small Resistance Artery Disease and ACE2 in Hypertension: A New Paradigm in the Context of COVID-19Cardiovascular Medicine Published on 2020-10-302022-10-31 Journal: Frontiers in Cardiovascular Medicine [Category] COVID-19, [키워드] ACE2 alteration angiotensin-converting enzyme 2 Arterial hypertension Artery binding blood flow cardiovascular catalytic domain cause cell entry clinical study Context contribute COVID-19 death Deleterious diagnosed with COVID-19 disease Endothelial dysfunction event events Evidence feature Hyperactivation Inflammation Inflammatory knowledge Local morbidity and mortality New Occurrence organs oxidative oxidative and inflammatory stress oxidative stress PAH paradigm pathology pathophysiology pathway Patient prevalent primary arterial hypertension Protein RAS regulate renin–angiotensin–aldosterone system reported resistance responsible risk SARS-CoV2 small resistance arteries small vessel Stress thrombosis tissue Vascular virus [DOI] 10.3389/fcvm.2020.588692 PMC 바로가기 [Article Type] Cardiovascular Medicine
Radiological Findings of COVID-19 Patients in ItalyOriginal Contribution Published on 2020-10-302022-10-28 Journal: BMC Public Health [Category] COVID-19, [키워드] analyzed assist Chest China Clinical finding Computed tomography COVID-19 COVID-19 cases COVID-19 patients CT scan database diagnosing Diagnosis diagnostic Efficacy evaluated finding indicated initial Italy National outbreak pandemic Patient performed positive positive COVID-19 problem Radiograph radiologic imaging radiological radiological finding radiology retrospective SARS-CoV2 similarity statistical analysis Strains Swab tested the disease Transmission were used with COVID-19 X-ray [DOI] 10.51894/001c.14505 PMC 바로가기 [Article Type] Original Contribution
A Time Frame for Testing Negative for SARS-COV2 in People with ObesityResearch Article Published on 2020-10-292023-06-15 Journal: Obesity facts [Category] MERS, SARS, [키워드] obesity overweight SARS-CoV2 [DOI] 10.1159/000511738 PMC 바로가기 [Article Type] Research Article
Molecular Insights into Human Transmembrane Protease Serine-2 (TMPS2) Inhibitors against SARS-CoV2: Homology Modelling, Molecular Dynamics, and Docking StudiesArticle Published on 2020-10-292022-10-30 Journal: Molecules [Category] COVID-19, MERS, SARS, [키워드] 3D structure ACE2 acute respiratory syndrome Amino acid binding affinity caused complexes coronavirus COVID-19 Dynamics Environment enzyme gabexate homology model host cell Human in silico inhibitors insight Ligand MD simulation molecular dynamics Molecular dynamics simulation novel corona virus pandemic performed predicted priming Protein protein-ligand required S protein SARS-CoV2 SARS-CoV2 infection sequence serine protease stability TMPRSS2 TMPRSS2 gene encode TMPS2 Treatment virus was performed [DOI] 10.3390/molecules25215007 PMC 바로가기 [Article Type] Article
The psychological impacts of COVID-19: a study of frontline physicians and nurses in the Arab worldShort Report Published on 2020-10-282022-10-30 Journal: Irish Journal of Psychological Medicine [Category] COVID-19, MERS, SARS, [키워드] Anxiety Arab world Burnout Care close contact collected data COVID-19 COVID-19 patient diagnose Effect Generalized globe HCW HCWs Health Healthcare professional Healthcare system healthcare worker mental health Nurse Oman pandemic participant Patient Perceived Perceived Stress Scale physician predictor Psychological psychological Impact SARS-CoV2 scale shown Stress Well-being WHO-5 Well-being Index with COVID-19 [DOI] 10.1017/ipm.2020.119 PMC 바로가기 [Article Type] Short Report