Plasma Concentrations and Safety of Lopinavir/Ritonavir in COVID-19 PatientsCOVID-19 환자에서 로피나비르/리토나비르의 혈장 농도 및 안전성Article Published on 2021-02-012022-09-11 Journal: Therapeutic drug monitoring [Category] 치료제, [키워드] absence Adverse drug reaction Adverse drug reactions antiviral activity average caution Concentration COVID-19 COVID-19 patient disorders dosage drug reaction Efficacy expected HIV HIV treatment in vivo increase in Inflammation Inflammatory interquartile lAbel limit Lopinavir Lopinavir/ritonavir moderate-to-severe COVID-19 Occurrence off-label off-label use one patient Patient plasma concentration plasma concentrations Previous studies reduced reported required Retrospective study Ritonavir Safety safety profile SARS-CoV-2 significantly suggested treated Treatment treatment for COVID-19 [DOI] 10.1097/FTD.0000000000000838 PMC 바로가기 [Article Type] Article
Safety and efficacy of hydroxychloroquine in 152 outpatients with confirmed COVID-19: A pilot observational studyObservational Study Published on 2021-02-012022-10-05 Journal: The American journal of emergency medicine [Category] 임상, [키워드] administration of hydroxychloroquine Adverse age arrhythmia Bazett formula clinical COVID-19 defined drug discontinuation Effect Efficacy Efficacy and safety Electrocardiography enrolled event group groups Hospitalization Hospitalized Hydroxychloroquine increased risk interquartile range interval investigated IQR majority median men molecular non-serious adverse occurred Outpatient Patient patients QT interval QT prolongation QTc QTc interval reaction risk Safe Safety severe COVID-19 single-center study Tachycardia the median the patient Treatment ventricular ventricular arrhythmia was measured with COVID-19 women ΔQTc [DOI] 10.1016/j.ajem.2020.12.014 PMC 바로가기 [Article Type] Observational Study
Emerging COVID‐19 vaccines: A rheumatology perspectiveArticle Published on 2021-02-012023-06-16 Journal: International journal of rheumatic diseases [Category] MERS, [키워드] Coronavirus disease 2019 rheumatology Safety Vaccine [DOI] 10.1111/1756-185X.14048 PMC 바로가기
Isolation and Evaluation of Probiotic Potential of Lactic Acid Strains From Healthy Equines for Potential Use in Salmonella InfectionArticle Published on 2021-01-312024-09-07 Journal: J Equine Vet Sci [Category] 살모넬라증, [키워드] equine lactobacillus Probiotic potential Safety Salmonella PMC 바로가기
Evaluation of the safety and efficacy of using human menstrual blood‐derived mesenchymal stromal cells in treating severe and critically ill COVID‐19 patients: An exploratory clinical trial중증 및 중환자 COVID-19 환자 치료에서 인간 월경혈유래 중간엽 기질 세포의 안전성 및 효능 평가: 탐색적 임상 시험Clinical Trial Published on 2021-01-272022-08-13 Journal: Clinical and Translational Medicine [Category] MERS, 임상, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 adverse event adverse events AEs Allogeneic alternative method caused chest imaging clinical trial Concomitant medication concomitant medications control group coronavirus coronavirus disease Coronavirus disease 2019 coronavirus disease 2019 (COVID‐19) COVID‐19 COVID‐19 patients Critical Critically ill died Dyspnea effective Efficacy enrolled experimental group exploratory Frequency groups incidence lack menstrual Mesenchymal stromal cell Mesenchymal stromal cells Mortality MSC MSC therapy MSCs multicenter nonrandomized not differ open‐label Patient patients problems proliferation respiratory Safety safety and efficacy SARS‐CoV‐2 secondary endpoint Secondary endpoints severe acute respiratory syndrome Coronavirus severe and critical patients significantly significantly lower Spread stromal cell stromal cells therapy treat treated Treatment Trial was measured were assessed [DOI] 10.1002/ctm2.297 PMC 바로가기 [Article Type] Clinical Trial
COVID-19 Response in Thailand and Its Implications on Future PreparednessArticle Published on 2021-01-262022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, MERS, [키워드] affected Analysis approach Asian cooperation country COVID-19 COVID-19 pandemic dimension disaster early stage effective Emergency engage framework Future Health HEDRM impacted impacts inclusive recovery Measures Mitigation pandemic plan public health reported Resilience resource response responses Safety Sendai Framework Spread Support Thailand health response the disease while [DOI] 10.3390/ijerph18031089 PMC 바로가기 [Article Type] Article
Immunogenicity and safety of a live herpes zoster vaccine in hematopoietic stem cell transplant recipients조혈모세포 이식 수혜자에서 생백신 대상포진 백신의 면역원성과 안전성Research Article Published on 2021-01-262023-05-23 Journal: BMC Infectious Diseases [Category] Fulltext, 대상포진, 두창, 수두, 홍역, [키워드] hematopoietic stem cell transplantation herpes zoster immunogenicity Safety Varicella zoster virus [DOI] 10.1186/s12879-021-05806-4 PMC 바로가기 [Article Type] Research Article
The History, Efficacy, and Safety of Potential Therapeutics: A Narrative Overview of the Complex Life of COVID-19잠재적 치료제의 역사, 효능 및 안전성: COVID-19의 복잡한 삶에 대한 서사적 개요Review Published on 2021-01-222022-09-10 Journal: International Journal of Environmental Research an [Category] 진단, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 adverse event adverse events caused clinical Clinical improvement Clinical studies clinical study conducted convalescent plasma coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 effective Efficacy Efficacy and safety evaluate Evidence Favipiravir FIVE history Hydroxychloroquine identify life limitation literature review narrative observational studies pandemic Potential profile public health Randomized controlled trial Randomized controlled trials RCTs Remdesivir reported researcher respiratory Safe Safety SARS-CoV-2 severe acute respiratory syndrome Coronavirus study participation Support the disease Therapeutics therapy Tocilizumab was used were used Withdrawal [DOI] 10.3390/ijerph18030955 PMC 바로가기 [Article Type] Review
Optimising Vaccine Dose in Inoculation against SARS-CoV-2, a Multi-Factor Optimisation Modelling Study to Maximise Vaccine Safety and EfficacyArticle Published on 2021-01-222022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] Accuracy Ad5 adenovirus-vectored vaccines adverse event calibrated can be used COVID-19 Critical Developing dose dose dynamics dose-dependent Dose-response Dosing Efficacy and safety estimates exceeded global pandemic identify Immunity IMPROVE in viral induce inoculation less optimal dose Optimising Particle recombinant adenovirus required Research Result Safety SARS-CoV-2 SARS-CoV-2 vaccine Seroconversion statistical model Vaccine viral particle Viral particles [DOI] 10.3390/vaccines9020078 PMC 바로가기 [Article Type] Article
Analysis of SteraMist ionized hydrogen peroxide technology in the sterilization of N95 respirators and other PPEArticle Published on 2021-01-212022-10-29 Journal: Scientific Reports [Category] Coronavirus, [키워드] approach Bacterial COVID-19 pandemic effective Efficacy Efficiency equipment filtration FIVE Frederick healthcare hydrogen peroxide Infectious diseases lab Laboratory Mask mitigate N95 mask N95 respirator occupational occupational health Particles Personal protective equipment PPE Quantitative reuse Safety sealed spore subsequent tested treat viral infection Volume was performed were assessed widespread [DOI] 10.1038/s41598-021-81365-7 PMC 바로가기 [Article Type] Article