Similarity between mutation spectra in hypermutated genomes of rubella virus and in SARS-CoV-2 genomes accumulated during the COVID-19 pandemic풍진 바이러스의 과돌연변이된 게놈과 COVID-19 전염병 동안 축적된 SARS-CoV-2 게놈의 돌연변이 스펙트럼 간의 유사성Research Article Published on 2020-10-022022-08-13 Journal: PLoS ONE [Category] MERS, SARS, 유전자 메커니즘, [키워드] accumulated accumulation Analysis APOBEC cytidine deaminase change characteristic COVID-19 pandemic cytidine Cytidine deaminase dataset Each enrichment event genomes genomic RNA human population hypermutated genome hypermutated genomes hypermutation individual isolate lead motif Mutation mutation mechanism mutation mechanisms mutational spectrum new SARS-CoV-2 pathological condition positive predicted preference Propagation reported RNA secondary structure RNA virus rubella rubella vaccine rubella vaccine virus rubella virus SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 mutation SARS-CoV-2 viruses SARS-CoV2 secondary structure sequenced similarity single base substitution single base substitutions single subject strand genomic RNA subclass substitutions suggested the SARS-CoV-2 virus virus isolate viruses [DOI] 10.1371/journal.pone.0237689 PMC 바로가기 [Article Type] Research Article
Viroinformatics approach to explore the inhibitory mechanism of existing drugs repurposed to fight against COVID-19Research article Published on 2020-10-012022-10-05 Journal: European journal of pharmacology [Category] 신약개발, 치료제, [키워드] ACE2 angiotensin-converting enzyme 2 approach binding Chloroquine clinical study coronavirus disease COVID-19 deep disease drug Drug repurposing Drug repurposition drugs effective enzyme explicit Favipiravir feature host receptor humans inhibitory involved limitation lockdown Measures mechanism Medicine molecular docking molecular dynamics simulations morbidity and mortality multi pandemic RdRP reduced Remdesivir Replication residue RNA RNA polymerase Safe SARS-CoV2 significantly Spike protein SSAA09E2 Structural analysis structural property treat Treatment unique viral entry Viroinformatics virus [DOI] 10.1016/j.ejphar.2020.173496 [Article Type] Research article
Varied clinical presentation and outcome of SARS-CoV-2 infection in liver transplant recipients: Initial experience at a single center in Madrid, Spain간 이식 환자에서 SARS-CoV-2 감염의 다양한 임상 양상 및 결과: 스페인 마드리드의 단일 센터에서 초기 경험Observational Study Published on 2020-10-012022-09-11 Journal: Transplant infectious disease : an official journa [Category] MERS, SARS, 임상, 진단, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Administered age baseline broad spectrum consequence coronavirus COVID-19 CT scan diagnosed died discharged home disease severity Drug interactions Dyspnea females Fever Follow-up Hydroxychloroquine immunomodulatory therapy Immunosuppression incidence Infection interferon liver Liver function liver transplant Lopinavir Lopinavir/ritonavir median median age modify one patient onset of symptoms outcome Outpatient Pandemics Patient patients patients with COVID-19 Pneumonia Prognosis question recipients regimen remained respiratory Ritonavir SARS-CoV-2 SARS-COV-2 infection SARS-CoV2 severe acute respiratory syndrome Coronavirus single center single-center Spain still hospitalized Symptoms therapy Tocilizumab transplantation Two patient two patients was used X-ray [DOI] 10.1111/tid.13372 PMC 바로가기 [Article Type] Observational Study
An in-silico approach to study the possible interactions of miRNA between human and SARS-CoV2Article Published on 2020-10-012023-07-05 Journal: Computational biology and chemistry [Category] SARS, [키워드] COVID19 Gene-ontology Hairpin in-silico miRNA SARS-CoV2 [DOI] 10.1016/j.compbiolchem.2020.107352 PMC 바로가기
Safety and efficacy of anti-il6-receptor tocilizumab use in severe and critical patients affected by coronavirus disease 2019: A comparative analysisComparative Study Published on 2020-10-012023-07-06 Journal: The Journal of Infection [Category] SARS, [키워드] COVID-19 IL-6 Orotracheal tube SARS-CoV2 Tocilizumab [DOI] 10.1016/j.jinf.2020.07.008 PMC 바로가기 [Article Type] Comparative Study
Causes of hypogeusia/hyposmia in SARS-CoV2 infected patientsArticle Published on 2020-10-012023-07-06 Journal: Journal of medical virology [Category] SARS, [키워드] coronavirus COVID-19 neurological SARS-CoV2 smelling tasting. [DOI] 10.1002/jmv.25903 PMC 바로가기
Pulmonary artery thrombi are co-located with opacifications in SARS-CoV2 induced ARDSArticle Published on 2020-10-012023-07-11 Journal: Respiratory medicine [Category] SARS, [키워드] COVID19 CT-scan CTPA Pulmonary artery thrombosis Pulmonary embolism SARS-CoV2 [DOI] 10.1016/j.rmed.2020.106135 PMC 바로가기
Vaccine Against Covid-19 Disease – Present Status of DevelopmentReview Published on 2020-10-012023-07-06 Journal: Indian journal of pediatrics [Category] SARS, [키워드] COVID-19 SARS-CoV2 Vaccine against SARS-CoV2. [DOI] 10.1007/s12098-020-03475-w PMC 바로가기 [Article Type] Review
The war against the SARS-CoV2 infection: Is it better to fight or mitigate it?Article Published on 2020-10-012023-07-11 Journal: Med Hypotheses [Category] SARS, [키워드] ACE2 COVID-19 hypertension Interleukins nitric oxide Phosphodiesterase type 5 inhibitors SARS-CoV2 [DOI] 10.1016/j.mehy.2020.110129 PMC 바로가기
[COVID-19: neurological manifestations : What we know so far]Review Published on 2020-10-012023-07-06 Journal: Radiologe [Category] SARS, [키워드] Acute disseminated encephalomyelitis Cerebrovascular complications Encephalitis magnetic resonance imaging NEUROLOGY SARS-CoV2 [DOI] 10.1007/s00117-020-00748-5 PMC 바로가기 [Article Type] Review