Virus-Like Particles of SARS-Like Coronavirus Formed by Membrane Proteins from Different Origins Demonstrate Stimulating Activity in Human Dendritic CellsResearch Article Published on 2008-07-162022-10-28 Journal: PLoS ONE [Category] Coronavirus, [키워드] activated activity Antibody Response baculovirus bat CD4+ T cell CD40 CD80 CD83 CD86 co-stimulatory molecule compared CoV cytokine Cytokines DC DCs demonstrated dendritic cell different DNA DNA vaccine evidenced Express expression finding Human IL-10 IL-6 immature incorporation indicated information inoculated insect cell labeling led to M protein membrane membrane protein mice Microscopy origin Particle Pathogenesis Population Protein response S protein SARS Coronavirus SARS CoV SARS-CoV SARS-CoV S SARS-like coronavirus secretion SL-CoV stimulate Stimulating T cell response the S protein TNF-α up-regulated Vaccine development Virus-like particle VLP VLPs western blot [DOI] 10.1371/journal.pone.0002685 PMC 바로가기 [Article Type] Research Article