The mosaic of autoimmunity – Finally discussing in person. The 13th international congress on autoimmunity 2022 (AUTO13) AthensArticle Published on 2022-10-012022-11-15 Journal: Autoimmunity reviews [Category] COVID19(2023년), SARS, 진단, [키워드] Abstract addition addressed AUTO13 autoantibodies Autoimmune Autoimmune disease Autoimmunity correlated correlation Course COVID-19 COVID-19 vaccine Critical Cytokine storm diagnostics disease Diseases example extreme Immunosuppressant International involved mechanism morbidity Mortality organ pandemic participant Pathways patients with COVID-19 SARS-CoV-2 severity syndrome systemic lupus erythematosus Systemic sclerosis the disease Therapies therapy while [DOI] 10.1016/j.autrev.2022.103166 PMC 바로가기
Characterization of coagulopathy and outcomes in cancer patients with severe COVID -19 illness: Longitudinal changes in hospitalized cancer patientsArticle Published on 2022-10-012022-11-15 Journal: Cancer Medicine [Category] COVID19(2023년), SARS, 바이오마커, [키워드] 1:1 Anderson blood cell count Cancer cancer patient Cancer patients CBC center change changes in characterization clinical clinical observations Coagulopathy Complete correlated COVID COVID-19 COVID-19 illness COVID-19 patient Critical CRP death disease elevated feature fibrinogen FIVE future risk had more help hematological hematological cancer Hospital admission Hospital stay Hospitalization Hospitalized IL-6 inflammatory markers interleukin-6 lack longitudinal Lymphocyte count management measure mechanical ventilation mechanism Mortality neutrophil Non-COVID-19 outcome outcomes Peripheral blood Platelet prognostic Prognostic factor required Retrospective analysis risk Risk assessment Serum ferritin severe COVID-19 illness Stratification survival thrombosis Thrombotic complications unique viral infection with COVID-19 [DOI] 10.1002/cam4.4753 PMC 바로가기
Promising natural products against SARS-CoV-2: Structure, function, and clinical trialsArticle Published on 2022-10-012022-11-15 Journal: Phytotherapy research : PTR [Category] COVID19(2023년), SARS, 치료제, [키워드] 3CLpro ACE2 activity acute respiratory syndrome addition analyzed antiinflammatory antivirals assessments Breakthrough infection caused clinical trial clinical trials coronavirus Coronaviruses COVID-19 Critical drug drug interaction drugs Effect effective enhancer Health immune Improvements inhibitory effect mechanism Mutation natural products Protein RdRP Research SARS-CoV-2 shown Spread Structure structures Vaccine virus Virus Disease [DOI] 10.1002/ptr.7580 PMC 바로가기
Challenges of data sharing in European Covid-19 projects: A learning opportunity for advancing pandemic preparedness and responseReview article Published on 2022-10-012022-10-05 Journal: The Lancet Regional Health - Europe [Category] 유전자 메커니즘, [키워드] approval challenge cohort study cohorts Compliance COVID-19 pandemic Critical data curation Data sharing European GDPR General Data Protection Regulation International machine learning mandatory Metadata National pandemic Patient Preparedeness producing protection public health recommendation Research SARS-CoV-2 submission Support [DOI] 10.1016/j.lanepe.2022.100467 [Article Type] Review article
Toward a big picture of COVID-19Article Published on 2022-10-012022-11-15 Journal: Pharmacology Research & Perspectives [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] addition available data benefit caused chronic inflammation clinical trial Corona COVID-19 Critical Culture cybernetics driven by drug eco ecosystem effort ENhance Epidemiology Evidence executive explain explicit Governance handling Inflammation knowledge Laboratory limitation Local lockdown management media mutant National occurred organization pandemic Pandemics pathology Perspective problem reflect Regulation Research SARS-CoV2 suggested System Treatment zoonoses zoonosis [DOI] 10.1002/prp2.996 PMC 바로가기
Clinical prediction models in hospitalized patients with COVID-19: A multicenter cohort studyArticle Published on 2022-10-012022-11-15 Journal: Respiratory medicine [Category] 진단, [키워드] Accuracy acute COVID-19 Admission age APACHE II asymptomatic infection calculated Care clinical Clinical decision rules COVID-19 COVID-GRAM Critical CURB-65 death died Hospital stay Hospitalized hospitalized patient IMPROVE In-hospital death independent predictor intubation Italian majority Mortality multicenter cohort study Negative predictive value novel coronavirus disease outbreak PaO2/FiO2 ratio Patient patients with COVID-19 Pneumonia Positive predictive value predict predictor Prognosis prognostic risk SARS-CoV-2 Sepsis severe respiratory failure SOFA [DOI] 10.1016/j.rmed.2022.106954 PMC 바로가기
Synthesis and structure-activity relationship study of saponin-based membrane fusion inhibitors against SARS-CoV-2SARS-CoV-2에 대한 사포닌계 막융합 억제제의 합성 및 구조-활성 관계 연구Article Published on 2022-10-012022-09-11 Journal: Bioorganic chemistry [Category] COVID19(2023년), SARS, 변종, 치료제, [키워드] antiviral agent Antiviral agents antiviral efficacy Cell cell entry Cell fusion Complex molecule Complex molecules synthesis component Compound coronavirus coronavirus variants COVID-19 Critical derivative develop Effectiveness endosomal experiment fusion Glucose host cell host cell membranes inhibit inhibited inhibitor inhibitors membrane fusion protease Saponin saponins SARS-CoV-2 SARS-CoV-2 entry SARS-CoV-2 variant SARS-CoV-2 variants Serine sugar synthesis the SARS-CoV-2 transmembrane [DOI] 10.1016/j.bioorg.2022.105985 PMC 바로가기 [Article Type] Article
Cystatin C is associated with adverse COVID-19 outcomes in diverse populationsResearch article Published on 2022-10-012022-10-05 Journal: iScience [Category] 바이오마커, 변종, 유전자 메커니즘, 임상, [키워드] 95% CI African analyzed association Cohort cohort of patient courses COVID-19 Critical cystatin C demonstrated European Factor functional Hospitalized hospitalized COVID-19 patient Host host response human metabolism ICU admission independent Logistic regression Mortality outcome Patient patients with COVID-19 performed plasma Population populations Predictive prognostic proteomics Stratification UKB Virology with COVID-19 [DOI] 10.1016/j.isci.2022.105040 [Article Type] Research article
COVID-19-associated liver injury: Clinical characteristics, pathophysiological mechanisms and treatment managementReview article Published on 2022-10-012022-10-05 Journal: Biomedicine & pharmacotherapy = Biomédecine & phar [Category] COVID19(2023년), SARS, 임상, 진단, 치료기술, 치료법, 치료제, [키워드] acute respiratory syndrome addition aggravate Asymptomatic caused Characteristics chronic liver disease cirrhosis clinical clinical manifestation Complication Coronavirus disease 2019 Coronavirus-2 COVID-19 COVID-19 patient Critical death disease dysfunction Epidemic extrapulmonary organs Factors hepatic function Hepatocellular carcinoma hypoxia immune increased risk infection with SARS-CoV-2 inflammatory factor storms Injury liver Liver damage Liver disease liver enzyme Liver function Liver injury liver transplant Liver transplantation management mechanism nonalcoholic fatty liver pathophysiological mechanism Patient patients prevalent public health reperfusion Respiratory disease risk SARS-CoV-2 severe disease Stress Treatment Vaccine [DOI] 10.1016/j.biopha.2022.113568 [Article Type] Review article
COVID-19-Associated Hospitalizations Among Vaccinated and Unvaccinated Adults 18 Years or Older in 13 US States, January 2021 to April 2022Article Published on 2022-10-012022-11-16 Journal: JAMA Internal Medicine [Category] COVID19(2023년), SARS, 변종, [키워드] adults hospitalized age association booster dose calculated Care Characteristics clinician Coverage COVID-19 COVID-19 vaccine Critical cross-sectional defined determine dose effort eligible Factor hospital Hospitalization Hospitalized hospitalized patient immunization information laboratory-confirmed SARS-CoV-2 infection lowest median medical condition network Older omicron outcome Patient percentage positive Practitioner predominant promote public health ranged risk factor SARS-CoV-2 test state table understanding vaccinated individuals vaccination variant were assessed were used with COVID-19 Year [DOI] 10.1001/jamainternmed.2022.4299 PMC 바로가기