Age-Adjusted Associations Between Comorbidity and Outcomes of COVID-19: A Review of the Evidence From the Early Stages of the PandemicPublic Health Published on 2021-08-062022-10-31 Journal: Frontiers in Public Health [Category] COVID-19, MERS, SARS, [키워드] age association Cancer chronic disease chronic health conditions Comorbidity conducted coronavirus COVID-19 COVID-19 pandemic Critical care death Diabetes Mellitus disease early stage eligible Evidence exacerbate for inclusion group Health hospitalisation hospitalised hospitalised COVID-19 patient hospitalised patient hypertension Increasing International Lung disease measure Mortality MOST obesity outcome outcomes pandemic progression PROTECT Quality reduce review risk robust severe COVID-19 severe disease significantly Stage Topic with COVID-19 [DOI] 10.3389/fpubh.2021.584182 PMC 바로가기 [Article Type] Public Health
Persistent Endothelial Dysfunction in Post-Acute COVID-19 Syndrome: A Case-Control StudyArticle Published on 2021-08-042022-10-28 Journal: Biomedicines [Category] COVID-19, [키워드] age alteration arterial oxygen tension Biomarkers cardiovascular risk factors case-control study clinical variables complications confounders Control convalescent COVID-19 patient convalescent COVID-19 patients coronavirus disease correlated correlation COVID-19 COVID-19 patient diffusing disability dysfunction Endothelial dysfunction endothelial function evaluated exercise exhibited expiratory female for inclusion Gender independent male males no significant difference outcomes Pathogenesis persistent pulmonary pulmonary impairment rehabilitation severity significantly higher significantly lower study population subgroup analysis Swab test syndrome unit Volume [DOI] 10.3390/biomedicines9080957 PMC 바로가기 [Article Type] Article
Relation Between Body Composition, Systemic Inflammatory Response, and Clinical Outcomes in Patients Admitted to an Urban Teaching Hospital with COVID-19COVID-19로 도시 교육 병원에 입원한 환자의 체성분, 전신 염증 반응 및 임상 결과 간의 관계Nutrition and Disease Published on 2021-08-032022-09-12 Journal: The Journal of Nutrition [Category] MERS, SARS, 진단, [키워드] Admission Body body composition changes characteristic clinical Clinical outcome collected Computed tomography COVID-19 criteria CT for inclusion greater high mortality Intensive male Mortality NLR obesity objective Patient positive PCR test radiological relation response Result sarcopenia severe respiratory illness significantly study inclusion systemic systemic inflammation Teaching therapy urban variables were assessed with COVID-19 [DOI] 10.1093/jn/nxab142 PMC 바로가기 [Article Type] Nutrition and Disease
Co-infections, secondary infections, and antimicrobial use in patients hospitalised with COVID-19 during the first pandemic wave from the ISARIC WHO CCP-UK study: a multicentre, prospective cohort studyArticles Published on 2021-08-012022-10-31 Journal: The Lancet. Microbe [Category] COVID-19, MERS, SARS, [키워드] Admission Against age analysed antimicrobial available data Bacterial infection bloodstream carbapenem case report form caused CCP-UK characterisation clinical clinically Co-infection collected Community concerning conducted Critical care Culture demographic Department development diagnosed eligible England Enterobacteriaceae Escherichia coli European excluded female finding for inclusion foundation Frequency funding Haemophilus influenzae highest hospital Hospital admission hospitalised Imperial College London Infection Inpatient Intervention IQR ISARIC ISARIC WHO CCP-UK Laboratory likelihood median Medical Research Council Melinda Gate microbiologically multicentre NIHR NIHR HPRU organism outcome pandemic pathogen Pathogens Patient patients patients with COVID-19 predominant prospective cohort study protection recorded respiratory SARS-COV-2 infection SARS-CoV-2 test Secondary infection secondary infections secondary respiratory infections Staphylococcus aureus target therapeutic unit University of Liverpool Wellcome Trust were excluded were recorded WHO with COVID-19 [DOI] 10.1016/S2666-5247(21)00090-2 PMC 바로가기 [Article Type] Articles
A seroprevalence survey of anti-SARS-CoV-2 antibodies among individuals 18 years of age or older living in a vulnerable region of the city of São Paulo, Brazil브라질 상파울루 시 취약 지역에 거주하는 18세 이상 개인을 대상으로 한 항 SARS-CoV-2 항체의 혈청유병률 조사Research Article Published on 2021-07-292022-09-12 Journal: PLoS ONE [Category] 진단, [키워드] 95% CI activities age anti-SARS-CoV-2 antibody asked Asymptomatic Asymptomatic case Asymptomatic cases Asymptomatic individuals Blood Brazil city Cluster Clusters collected conducted COVID-19 cross-sectional demonstrated Disease surveillance distribution eligible evaluate Families family for inclusion greater healthcare healthcare service individual infected individual infected individuals Older pandemic participant populations Prevalence proportion regions resulting SARS-CoV-2 second wave selected serology testing seroprevalence survey Serosurvey Serosurveys Signs and symptoms stratified study inclusion Surveillance sustained Symptom the disease vaccination vulnerable population [DOI] 10.1371/journal.pone.0255412 PMC 바로가기 [Article Type] Research Article
A systematic review on the effects of Echinacea supplementation on cytokine levels: Is there a role in COVID-19?사이토카인 수치에 대한 에키네시아 보충제의 효과에 대한 체계적인 검토: COVID-19에 역할이 있습니까?Articles from the Vaccines, Immune Response, Therapeutic Interventions and COVID-19 Special Issue Published on 2021-07-292022-09-10 Journal: Metabolism Open [Category] 비임상, [키워드] Abstract administration AMED anti-inflammatory cytokine appear ARDS, acute respiratory distress syndrome breath caused CCL, C–C motif ligand chemokine changes changes in CINAHL clinical clinical trial clinical trials COVID-19 COVID-19 mortality COVID-19, Coronavirus disease 2019 criteria CSF, Colony-stimulating factor cytokine cytokine level cytokine levels Cytokine release syndrome Cytokine storm Cytokines data extraction database decrease Echinacea Effect Effectiveness Evidence Ex vivo Factor for inclusion GM-CSF, granulocyte-macrophage colony-stimulating factor herbal medicine Highlights identify IFN, interferon IL-10 IL-6 IL-8 IL, interleukin immune modulation immune system in vitro increase in involved management MCP, monocyte chemoattractant protein MIP, macrophage inflammatory protein modulation Novel coronavirus OVID patients with COVID-19 pro-inflammatory cytokine pro-inflammatory cytokines qualitative analysis Research respiratory Respiratory illness risk of bia SARS-CoV-2 SARS-CoV-2, Severe acute respiratory syndrome coronavirus 2 SARS, Severe acute respiratory syndrome severe COVID-19 suggested systematic review TFN, tumor necrosis factor therapeutic effect therapeutic effects title TNF Treatment Trial unique was used while [DOI] 10.1016/j.metop.2021.100115 PMC 바로가기 [Article Type] Articles from the Vaccines, Immune Response, Therapeutic Interventions and COVID-19 Special Issue
Cohort profile: A Prospective Household cohort study of Influenza, Respiratory syncytial virus and other respiratory pathogens community burden and Transmission dynamics in South Africa, 2016–2018Original Article Published on 2021-07-232022-10-30 Journal: Influenza and Other Respiratory Viruses [Category] Coronavirus, MERS, SARS, [키워드] Analysis asymptomatic infection burden Cohort Cohort profile cohort study collected Community Date eligible enrolled enrolment finding for inclusion fraction Frequency Future household household contact household transmission incidence include index case individual Infection Influenza Influenza virus initiated Nasopharyngeal swab nasopharyngeal swabs over participant PCR plan polymerase chain positive Prospective Randomly respiratory respiratory pathogen respiratory syncytial virus RSV SARS‐CoV‐2 SARS‐CoV‐2 infection selected serology South Africa symptomatic tested Transmission virus virus transmission [DOI] 10.1111/irv.12881 PMC 바로가기 [Article Type] Original Article
Evaluation of saliva as a complementary technique to the diagnosis of COVID-19: a systematic review코로나19 진단을 위한 보완적 기법으로서의 타액 평가: 체계적 고찰Review Published on 2021-07-202022-09-10 Journal: Medicina Oral, Patología Oral y Cirugía Bucal [Category] SARS, 치료기술, [키워드] addition Affect America analyzed article Asia asymptomatic patient asymptomatic patients caused Chain Reaction Clinical use complementary Contagion coronavirus Coronavirus 2019 COVID-19 COVID19 Cross-sectional studies cross-sectional study detect Diagnosis diagnosis of COVID-19 Diagnostic method disease early stage early stages ELISA enzyme enzyme-linked immunosorbent enzyme-linked immunosorbent assay Europe evaluated for inclusion gold gold standard healthcare professionals IgA IgG IgM isothermal amplification item majority Material and Method Nasopharyngeal swab Non-invasive offer Patient performed polymerase chain polymerase chain reaction Real-Time Reverse Transcription Polymerase Chain Reaction receiving reducing Reporting respiratory Result reverse transcription reverse transcription polymerase chain reaction review risk RT-LAMP RT-qPCR Saliva saliva sample saliva samples SARS-CoV SARS-CoV-2 SARS-CoV-2 virus searched selected sensitivity Spectroscopy systematic review systematic reviews the disease the SARS-CoV-2 virus upper respiratory tract Viral Viral RNA [DOI] 10.4317/medoral.24424 PMC 바로가기 [Article Type] Review
Relative sensitivity of anterior nares and nasopharyngeal swabs for initial detection of SARS-CoV-2 in ambulatory patients: Rapid review and meta-analysis외래 환자에서 SARS-COV-2의 초기 탐지를위한 전방 나르 및 비 인두 면봉의 상대적 민감도 : 빠른 검토 및 메타 분석Review Published on 2021-07-202022-09-10 Journal: PLoS ONE [Category] SARS, 진단, 치료기술, [키워드] ambulatory patients assessments bioRxiv Chain Reaction Characteristics Confusion diagnosing Diagnosis diagnosis of SARS-CoV-2 Extracted for inclusion gold gold standard greater heterogeneity Infection initial less medRxiv Meta-analysis nare nasal nasal swab nasal swabs nasopharyngeal specimen Nasopharyngeal swab nasopharyngeal swabs Negative predictive value Patient performed Personal protective equipment Polymerase chain reaction testing Population predictive values PROSPERO provided Rapid reduced reference standard Registered relative SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections sensitivity specimen Study design study outcomes subject Swab [DOI] 10.1371/journal.pone.0254559 PMC 바로가기 [Article Type] Review
BCG-induced non-specific effects on heterologous infectious disease in Ugandan neonates: an investigator-blind randomised controlled trial우간다 신생아의 이종 감염성 질환에 대한 BCG- 유도 비특이적 영향 : 조사관 맹인 무작위 대조 시험Articles Published on 2021-07-012022-09-06 Journal: The Lancet. Infectious Diseases [Category] Communicable Disease, [키워드] 1:1 Abstract addition age all-cause mortality Alter analysed analyses assigned BCG BCG vaccination benefit Birth blind block size block sizes blood sample Blood samples change clinically clinician Comparisons computer-generated Concentration Consent contributed Controlled Controlled trial Cord blood discharged Effect Effects eligible enrolled Entebbe Families finding Follow-up for inclusion funding geometric geometric mean geometric mean ratios gestational age group hazard ratio healthy hepcidin Heterologous hospital IFNγ IL-10 IL-1β IL-6 IL1B IL6 immunological incidence increase in Infant Infants infections Infectious disease inhibited Innate immunity international standard investigated investigators life Luganda material medical intervention modified intention-to-treat mononuclear cell morbidity morbidity and mortality mother Neonatal neonatal period no significant difference non-specific number outcome parent parents participant Peripheral blood Peripheral blood mononuclear cells primary clinical outcome promoter promoter region PROTECT randomisation randomised randomised controlled trial Randomly receive recruited reduce reductions reductions in Registered required saturation Standard Standard dose stratified by sex TNF Transferrin translation Trial Tuberculosis Uganda vaccination Wellcome Trust were excluded with HIV withdrawn [DOI] 10.1016/S1473-3099(20)30653-8 PMC 바로가기 [Article Type] Articles