SARS-CoV-2 introduction and lineage dynamics across three epidemic peaks in Southern Brazil: massive spread of P.1브라질 남부의 세 전염병 정점에 걸친 SARS-CoV-2 도입 및 계보 역학: P.1의 대규모 확산Article Published on 2021-12-012022-09-11 Journal: Infection, genetics and evolution : journal of mol [Category] SARS, 변종, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Analysis analyzed B.1 B.1.1 B.1.1.28 B.1.1.33 Brazil circulating Combination contributing to coordination coronavirus COVID-19 dataset Deletion deletions disease disease control dispersion Epidemic epidemic peak Epidemic peaks genetic diversity genomes genomic genomic diversity Genomic surveillance GISAID Health authority highlighting International Lineage lineages Mutation P.1 P.1 lineage P.2 phylogenetic inference Regional reported Rio Grande SARS-CoV-2 SARS-CoV-2 datasets SARS-CoV-2 genome SARS-CoV-2 genomes SARS-CoV-2 lineage sequence sequenced severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 spike mutation Spread Transmission viral dynamics [DOI] 10.1016/j.meegid.2021.105144 PMC 바로가기 [Article Type] Article
Atypical Prolonged Viral Shedding With Intra-Host SARS-CoV-2 Evolution in a Mildly Affected Symptomatic PatientMedicine Published on 2021-11-262022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] acute respiratory syndrome affected Analysis Asymptomatic Atypical B.1.1.28 Brazil caused coronavirus discharge event genetic diversity genomic Host immune response increase in individual infected patients Infection Intervention intra-host evolution knowledge Lineage male Manifestations measure outcome Patient performed prevalent Prolonged prolonged RNA viral shedding respiratory virus RNA SARS-CoV-2 SARS-CoV-2 RNA SARS-CoV-2 virus sgRNA shedding Spread Symptoms the SARS-CoV-2 upper respiratory tract viral clearance Viral RNA viral shedding [DOI] 10.3389/fmed.2021.760170 PMC 바로가기 [Article Type] Medicine
The high diversity of SARS-CoV-2-related coronaviruses in pangolins alerts potential ecological risks천산갑에서 SARS-CoV-2 관련 코로나바이러스의 높은 다양성은 잠재적인 생태학적 위험을 경고합니다Article Published on 2021-11-182022-09-11 Journal: Zoological research [Category] SARS, 유전자 메커니즘, 치료기술, [키워드] Analysis anticipated Asia capture sequencing Chinese coronavirus CoVs Critical Customs Diversity DNA ecological English Evolution Genetic genetic diversity genome sequence Guangxi indicated individual mitochondrial mitochondrial DNA mtDNA muscle muscles Outbreaks pangolin pangolin-CoV pangolins pathogenic phylogenetic analyses phylogeographic analysis positive Recombination reservoir risk SARS-CoV-2 screened Sequencing solution Transmission understanding zoonotic zoonotic origin [DOI] 10.24272/j.issn.2095-8137.2021.334 PMC 바로가기 [Article Type] Article
Human immune diversity: from evolution to modernity Reviews Published on 2021-11-182022-10-05 Journal: Nature Immunology [Category] 변종, 유전자 메커니즘, [키워드] age allele Analysis associations Defense Denisovan develop disease environmental exposure Evolution explain extreme genetic diversity Human Human immune system identify immune Interaction loci maintain mechanism Microbiome Migration Neanderthal Pathogens pathway plethora provide Sex variable Variation [DOI] 10.1038/s41590-021-01058-1 [Article Type] Reviews
Fecal Carriage and Molecular Characterization of Carbapenemase-Producing Enterobacterales in the Pediatric Population in QatarResearch Article Published on 2021-11-102022-10-30 Journal: Microbiology Spectrum [Category] Coronavirus, MERS, SARS, [키워드] Klebsiella pneumoniae Arabian Peninsula Asymptomatic carrier Carbapenemase Care carriage carrier Characteristics characterization characterized children Comorbidity coronavirus disease country CPE dominant E. coli Endemic enzyme Escherichia coli exhibited expressed fecal Genes genetic diversity Genotype Health hospital implementation incidence International introduced isolate Klebsiella pneumoniae knowledge Local molecular Multiple NDM OXA-48 Patient patients pediatric pneumoniae Population produced rectal sequence Sequencing strain swab sample Travel variant was used whole-genome sequencing [DOI] 10.1128/Spectrum.01122-21 PMC 바로가기 [Article Type] Research Article
Genomic diversity of SARS-CoV-2 in MalaysiaBioinformatics Published on 2021-11-032022-10-28 Journal: PeerJ [Category] COVID-19, [키워드] A701V accumulated Algorithm analysed analyses approved Asian association circulating Clustering complexes Consequences Continuous country COVID-19 pandemic D614G distribution Emergency use epidemiological examined Genes Genetic genetic change genetic diversity Genome genomic GISAID Health help immune evasion isolate Lineage lineages Linkage disequilibrium Malaysia massive minimum Mutation mutations new SARS-CoV-2 Non-synonymous nucleotide substitution ORF1ab performed populations Public ranged researchers Result SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 virus sequence sequenced Seven Spread Surveillance tree Vaccine variant viral genome Viral genome sequencing viral nucleotide virus [DOI] 10.7717/peerj.12449 PMC 바로가기 [Article Type] Bioinformatics
Explosive nosocomial outbreak of SARS-CoV-2 in a rehabilitation clinic: the limits of genomics for outbreak reconstruction재활 클리닉에서 SARS-CoV-2의 폭발적인 병원 발병: 발병 재구성을 위한 게놈의 한계Article Published on 2021-11-012022-09-11 Journal: The Journal of hospital infection [Category] SARS, 유전자 메커니즘, [키워드] 95% CI 95% confidence interval acquisition acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus-2 adjusted odds ratio Analysis Bayesian framework case-control study clinical Cluster Coronavirus-2 Coverage COVID-19 epidemiological data events excess expected Explosive fraction genetic diversity Genome genomes genomic greater HCW HCWs healthcare healthcare worker Healthcare workers Healthcare-associated infection highlight implementation index case Infection infection control Infection prevention Infection prevention and control investigated involved isolate likelihood limit Limited Limited genetic diversity Long-term care long-term care facilities Measures nosocomial nosocomial COVID-19 Nosocomial outbreaks outbreak Outbreak investigation pathogen Patient patients peak Phylogenetic tree Phylogeny Prevention and control reconstructed reconstruction rehabilitation Reproduction number resulting risk risk factor Risk factors SARS-CoV-2 SARS-CoV-2 transmission scale Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus-2 significantly statistical Transmission transmission pattern was performed was used WGS Whole-genome sequence [DOI] 10.1016/j.jhin.2021.07.013 PMC 바로가기 [Article Type] Article
Characterization of the emerging B.1.621 variant of interest of SARS-CoV-2SARS-CoV-2의 관심 대상인 새로운 B.1.621 변이체의 특성화Article Published on 2021-11-012022-09-11 Journal: Infection, genetics and evolution : journal of mol [Category] SARS, 변종, 유전자 메커니즘, [키워드] accumulation acute respiratory syndrome acute respiratory syndrome coronavirus affecting Amino acid amino acid change amino acid changes B.1.621 binding characterization circulating coronavirus E484K emergence escape Evolution fixation Frequency genetic diversity Genome sequencing herd immunity identify Immunity insertion Lineage N-terminal domain N501Y Nanopore natural infection Neutralizing antibodies P681H processed Protein protocol rapid increase RBD Receptor binding domain required S1/S2 cleavage site SARS-CoV-2 severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 Spike protein Substitution the Spike variant Variant of interest (VOI). virus transmissibility [DOI] 10.1016/j.meegid.2021.105038 PMC 바로가기 [Article Type] Article
Survey of SARS-CoV-2 genetic diversity in two major Brazilian cities using a fast and affordable Sanger sequencing strategy빠르고 저렴한 Sanger 염기서열분석 전략을 사용하여 브라질의 두 주요 도시에서 SARS-CoV-2 유전적 다양성 조사Article Published on 2021-11-012022-09-11 Journal: Genomics [Category] SARS, 변종, 치료기술, [키워드] amplify approach China circulating detect diagnostic procedures disease severity dissemination dominant followed by fragment fragment of genetic diversity genetic variants genetic variants. immunodeficiency less management measles virus P.2 variant Patient Patient management primer Primers Protein Rapid Sanger sequencing SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 variant SARS-CoV-2 variants spike Spike protein Spread survey the SARS-CoV-2 genome the Spike transmission rates Vaccine variant variants variants of SARS-CoV-2 virus virus genotypes [DOI] 10.1016/j.ygeno.2021.10.015 PMC 바로가기 [Article Type] Article
Plasmodium vivax From Duffy-Negative and Duffy-Positive Individuals Share Similar Gene Pools in East AfricaArticle Published on 2021-10-282024-08-28 Journal: Nanoscale [Category] 말라리아, [키워드] Duffy-negative East Africa genetic diversity Plasmodium vivax transmission pathways.