metabolite – Page 11 – Communicable Diseases Research

Vitamin D regulation of immune function during covid-19

Article

Published on 2022-01-292022-10-28
Journal: Reviews in Endocrine & Metabolic Disorders [Category] Coronavirus, COVID19(2023년), Fulltext, SARS,

[키워드] Activation adaptive Adaptive immunity airway epithelia alveolar Alveolar macrophages calcitriol Cathelicidin Cell chemokine clearance CYP27B1 cytokine Cytokine storm dead demonstrated dysregulation ENhance enzyme epithelia Express expresse help immune immune cells immune function infect Infection innate immune system Innate immunity investigated Ligand Local Lower respiratory tract lung macrophages mechanism metabolite modulating morbidity and mortality pandemic pathogen pathway pneumocyte producing Proinflammatory cytokine Proinflammatory response pulmonary Pulmonary alveolar macrophage reduce Regulation released respiratory pathogen rising SARS-CoV2 shown subsequent VDR viral infection viral neutralization virus Vitamin D Vitamin D receptor
[DOI] 10.1007/s11154-021-09707-4 PMC 바로가기 [Article Type] Article

Integrated histopathological, lipidomic, and metabolomic profiles reveal mink is a useful animal model to mimic the pathogenicity of severe COVID-19 patients

통합된 조직병리학, 지질학 및 대사체 프로필은 밍크가 심각한 COVID-19 환자의 병원성을 모방하는 유용한 동물 모델임을 보여줍니다

Article

Published on 2022-01-282022-09-10
Journal: Signal Transduction and Targeted Therapy [Category] Fulltext, SARS, 바이오마커, 진단, 치료법, 치료제,

[키워드] Absorption accompanied activated Activation acute respiratory syndrome acute respiratory syndrome coronavirus alteration alveolar damage amino acids Analysis animal model Anti-inflammatory characterized cholesterol contributed coronavirus correlated COVID-19 patients demonstrated Diffuse alveolar damage digestion digestive distribution downregulated dysregulation effective Effects Endocrine fatal COVID-19 feature fetal hepatic dysfunction highlight histological histopathological Human immune dysregulation immune systems immunomodulating Infection Infectious diseases Inflammatory response inoculation Kynurenine Kynurenine pathway lesion Lipid lipids Macrophage macrophage activation macrophages melatonin metabolic pathways metabolite metabolites metabolomic observation pathogenicity pathophysiological feature Patient post inoculation potential biomarkers profile Proteins reported Research respiratory SARS-CoV-2 severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 severe COVID-19 patient significantly Steroids transmitted Treatment strategies Vaccine Viral Viral protein vitamins was related widespread
[DOI] 10.1038/s41392-022-00891-6 PMC 바로가기 [Article Type] Article

Chaetomugilins and Chaetoviridins—Promising Natural Metabolites: Structures, Separation, Characterization, Biosynthesis, Bioactivities, Molecular Docking, and Molecular Dynamics

Review

Published on 2022-01-272022-10-30
Journal: Journal of Fungi [Category] COVID-19,

A New Butyrate Releaser Exerts a Protective Action against SARS-CoV-2 Infection in Human Intestine

새로운 부티레이트 방출제는 인간의 장에서 SARS-CoV-2 감염에 대한 보호 조치를 취합니다

Article

Published on 2022-01-272022-09-10
Journal: Molecules [Category] SARS, 유전자 메커니즘, 치료제,

[키워드] ACE2 Action Activation acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 administration alteration angiotensin angiotensin-converting enzyme-2 Antiviral antiviral response butyramide Butyrate carbamoyl Characteristics coronavirus COVID-19 Cytokines Defense defense mechanisms Diseases enterocytes enzyme expression FBA functional Gut gut microbiome Host Human IL-15 infected cells Infection Infectious diseases intestinal models investigated involved limit MCP-1 mechanism metabolite Microbiome modulate monocyte monocyte chemoattractant protein-1 neuropilin Neuropilin-1 New NF-kB NRP1 nuclear oral administration Pathways Patient presenting pro-inflammatory cytokine pro-inflammatory cytokines protease Protective receptor reduce reduced reducing regulate Releaser reported respiratory SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2-infected cells Serine serine 2 several gene several genes severe acute respiratory syndrome Coronavirus small intestinal biopsy small intestine TMPRSS2 TNF-α transmembrane transmembrane protease serine 2 up-regulation viral infection
[DOI] 10.3390/molecules27030862 PMC 바로가기 [Article Type] Article

Crosstalk Between the Gut Microbiota and Epithelial Cells Under Physiological and Infectious Conditions

Cellular and Infection Microbiology

Published on 2022-01-272022-10-31
Journal: Frontiers in Cellular and Infection Microbiology [Category] Coronavirus, SARS,

Disturbed lipid and amino acid metabolisms in COVID-19 patients

COVID-19 환자의 지질 및 아미노산 대사 장애

Original Article

Published on 2022-01-222022-09-10
Journal: Journal of Molecular Medicine (Berlin, Germany) [Category] 바이오마커,

[키워드] alteration Amino acid amino acid metabolism Analysis arachidonic acid arginine Biomarker control patients coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient COVID-19 patients Disturbed GABA gamma-aminobutyric acid Glutamine Healthcare systems hospitalized COVID-19 patient identification impacted indicated Infection information Intervention lead matched controls metabolic disturbance metabolic disturbances metabolic pathway metabolic pathways metabolism metabolisms metabolite metabolomics pandemic pathway Pathways Patient performed plasma plasma sample plasma samples reduced sensitivity severe COVID-19 significantly sphingolipid Stratification supplementary material System systemic reaction systemic reactions therapeutic target therapeutic targets Tryptophan tyrosine Viral viral infection
[DOI] 10.1007/s00109-022-02177-4 PMC 바로가기 [Article Type] Original Article

Metabolic biomarkers related to cardiac dysfunction in metabolic-dysfunction-associated fatty liver disease: a cross-sectional analysis

Article

Published on 2022-01-182022-10-04
Journal: Nutrition & Diabetes [Category] 바이오마커,

Activation of TCA cycle restrains virus-metabolic hijacking and viral replication in mouse hepatitis virus-infected cells

Research

Published on 2022-01-182022-11-01
Journal: Cell & Bioscience [Category] COVID-19,

[키워드] activate Activation acute respiratory syndrome caused Cell cellular coronavirus coronavirus disease COVID-19 Efficacy endogenous Fatty acid fatty acids Glutamine Glycolysis Host Infection inhibitor Intervention introduced investigated metabolism metabolite MHV Mitochondria mitochondrial metabolism mouse hepatitis mouse hepatitis virus NAD+ nicotinamide riboside NR pandemic pyruvate Replication reported Result SARS-CoV-2 significantly supplementary material suppress suppresse suppressed survival TCA cycle therapeutic Therapeutic molecule therapy for COVID-19 Transport viral replication virus virus-infected cell
[DOI] 10.1186/s13578-021-00740-z PMC 바로가기 [Article Type] Research

In Silico Studies on Psilocybin Drug Derivatives Against SARS-CoV-2 and Cytokine Storm of Human Interleukin-6 Receptor

SARS-CoV-2 및 인간 인터루킨-6 수용체의 사이토카인 폭풍에 대한 실로시빈 약물 유도체에 대한 실리코 연구

Immunology

Published on 2022-01-142022-09-11
Journal: Frontiers in Immunology [Category] SARS, 치료제,

Comparative Metabolomics and Proteomics Reveal Vibrio parahaemolyticus Targets Hypoxia-Related Signaling Pathways of Takifugu obscurus

Immunology

Published on 2022-01-132022-11-01
Journal: Frontiers in Immunology [Category] COVID-19,