A highly immunogenic and effective measles virus-based Th1-biased COVID-19 vaccine
면역원성이 높고 효과적인 홍역 바이러스 기반 Th1 편향 코로나19 백신
530
Published on
Journal: Proceedings of the National Academy of Sciences of [Category] MERS, SARS, 변종, 진단, 치료기술,
Journal: Proceedings of the National Academy of Sciences of [Category] MERS, SARS, 변종, 진단, 치료기술,
[키워드] accelerated
acute respiratory syndrome
acute respiratory syndrome coronavirus
acute respiratory syndrome coronavirus-2
adaptive
Adaptive immunity
addition
analyzed
antibody
antiviral efficacy
Arm
backbone
candidate
caused
CD4
CD8
Coronavirus-2
country
COVID-19
COVID-19 pandemic
COVID-19 vaccine
COVID-19 vaccines
death
deaths
effective
effective immunity
Effective vaccines
effort
experiments
expressing
full-length S protein
functional immune response
genomic position
gravity
hamster
identify
IgG antibody
immune
immune responses
Immunity
immunogenic
immunopathology
in vivo
induce
insertion
killing
measles
measles vaccine platform
measles virus
mice
modulated
mouse
mouse-adapted SARS-CoV-2
multifunctional
Neutralizing
Patient
Protective
public health
respiratory
response
S protein
S protein expression
Safe
SARS-CoV-2
SARS-CoV-2 spike glycoprotein
Severe acute respiratory syndrome
severe acute respiratory syndrome Coronavirus
Significance
significantly lower
situation
solution
spike glycoprotein
Spread
Support
T cell
T cell response
T cell responses
Th1 immune bias
the SARS-CoV-2
Threats
vaccination
Vaccine
vaccine candidate
variant
virus
virus load
yielding
[DOI] 10.1073/pnas.2014468117 PMC 바로가기 [Article Type] 530
[DOI] 10.1073/pnas.2014468117 PMC 바로가기 [Article Type] 530