Mesenchymal Stem Cells (MSCs) as a Potential Therapeutic Strategy in COVID-19 Patients: Literature ResearchCell and Developmental Biology Published on 2020-11-192022-10-31 Journal: Frontiers in Cell and Developmental Biology [Category] COVID-19, [키워드] anti-inflammatory activity ARDS Biology cell-based therapies Cell-based therapy Characteristics China coronavirus COVID-19 COVID-19 disease COVID-19 patients Critical Critical case Cytokine storm dimension effective therapy Engineering Health literature lung Medicine mesenchymal stem cell Mesenchymal stem cells MSC MSCs outbreak outcome pandemic Pathologies Pneumonia positive Potential Pulmonary edema pulmonary inflammation raised reported representing respiratory responsible SARS-CoV-2 Secretome shown specific treatment STEM Strategy Symptoms symptoms of COVID-19 therapeutic potential therapeutic strategy these cell Treatment Vaccine were used [DOI] 10.3389/fcell.2020.602647 PMC 바로가기 [Article Type] Cell and Developmental Biology
COVID‐19 therapy with mesenchymal stromal cells (MSC) and convalescent plasma must consider exosome involvement: Do the exosomes in convalescent plasma antagonize the weak immune antibodies?중간엽 기질세포(MSC)와 회복기 혈장을 이용한 코로나19 치료는 엑소좀 침범을 고려해야 한다: 회복기 혈장의 엑소좀은 약한 면역 항체를 길항하는가?Review Published on 2020-11-142022-09-12 Journal: Journal of Extracellular Vesicles [Category] MERS, 진단, [키워드] acting activated Administered affected aggregate antagonistic antibody best biologic Biologic therapy Cell Cell therapy clinically convalescent plasma COVID‐19 COVID‐19 patients COVID‐19 COVID‐19 antibodies COVID‐19 convalescent exosomes cytokine Cytokine storm deficiencies disease Effect Effects Evidence Exosome Exosomes expected extracellular vesicle Extracellular vesicles immune immune resistance immune response in vivo Infection lung dysfunction mechanisms Mesenchymal stromal cells miRNA miRNAs modulating MSC MSCs Nanoparticles parental Patient plasma Pneumonia responsible resulting severe pneumonia shown stromal cell stromal cells T cell tendency the antibody therapeutic therapy transfer treat Vascular vascular insufficiency virus [DOI] 10.1002/jev2.12004 PMC 바로가기 [Article Type] Review
Transplantation of Mesenchymal Stem Cells: A Potential Adjuvant Therapy for COVID-19Bioengineering and Biotechnology Published on 2020-11-052022-10-31 Journal: Frontiers in Bioengineering and Biotechnology [Category] COVID-19, [키워드] acute respiratory syndrome adjuvant ALI/ARDS anti-apoptotic Anti-inflammation Anti-inflammatory antiviral agent approved causative pathogen clinical trial clinical trials coronavirus Coronavirus-2 COVID-19 Cytokine storm Effect Efficacy immunomodulation immunomodulatory mechanisms mesenchymal stem cell Mesenchymal stem cells MSC MSCs Pathogenesis Potential provide public health threat regenerative effect Research Safe SARS-CoV-2 STEM therapeutic effect therapeutic strategy therapy transplantation Treatment Vaccine virus infection [DOI] 10.3389/fbioe.2020.557652 PMC 바로가기 [Article Type] Bioengineering and Biotechnology
New normal: two aspects of adipose tissue in COVID-19-treat and threat?Article Published on 2020-11-012023-07-12 Journal: Expert opinion on biological therapy [Category] SARS, [키워드] ACE2 Adipose tissue ADSC COVID19 hypertrophied MSC stromal cells. [DOI] 10.1080/14712598.2020.1822812
Stem cell therapy for COVID‐19, ARDS and pulmonary fibrosisReview Published on 2020-10-242022-10-31 Journal: Cell Proliferation [Category] COVID-19, MERS, SARS, [키워드] acute respiratory distress acute respiratory syndrome alveolar epithelial cell ARDS cause caused Cell clinical trial clinical trials coronavirus Coronavirus disease 2019 COVID‐19 COVID‐19 patient COVID‐19 CRS Cytokine release syndrome Cytokines derivative Efficacy endothelial Exosomes Factor Factors FGF fibroblast function growth hearts HGF illnesses immune cells immune system KGF lung Mesenchymal stem cells MSC MSCs MSCs therapy Necrosis other organ paracrine Pathogenesis pathogenic Patient potential mechanism Potential treatment preclinical studies preclinical study progression promote PROTECT Protein pulmonary fibrosis quantified Registered regulate respiratory infectious disease SARS‐CoV‐2 secrete secreting secretion shown stem cell Stem cell therapy suggested supportive care syndrome the disease therapeutic therapeutic potential therapy tissue repair TNF‐α Treatment variety Vascular VEGF [DOI] 10.1111/cpr.12939 PMC 바로가기 [Article Type] Review
Potential application of mesenchymal stem cells and their exosomes in lung injury: an emerging therapeutic option for COVID-19 patientsReview Published on 2020-10-152022-10-29 Journal: Stem Cell Research & Therapy [Category] COVID-19, MERS, SARS, [키워드] acute lung injury alveolar fluid clearance applicability approved ARDS characterized clinical study clinical trial clinical trials Consensus correlation COVID-19 COVID-19 pandemic COVID-19 patient COVID-19 patients effective effective therapy Efficacy endothelial ENhance epithelial Exosome global public health highlight impacted Infection International less lung mechanism of action mesenchymal stem cell MSC MSC therapy MSCs Pneumonia Potential promote reduce Registered risk Safe SARS-CoV-2 stem cell stem cells the cytokine storm the SARS-CoV-2 therapeutic therapeutic effect therapeutic option therapy Thromboembolism treat treating COVID-19 patients Treatment unique [DOI] 10.1186/s13287-020-01963-6 PMC 바로가기 [Article Type] Review
Research progress on Mesenchymal Stem Cells (MSCs), Adipose-Derived Mesenchymal Stem Cells (AD-MSCs), Drugs, and Vaccines in Inhibiting COVID-19 DiseaseReview Article Published on 2020-10-012022-10-28 Journal: Aging and Disease [Category] COVID-19, [키워드] acute respiratory distress Adipose Stem Cells administration affected Anti-inflammatory Anti-viral Anti-viral therapy antiviral therapy caused cellular clinically coagulation dysfunction Complication coronavirus 2 coronavirus disease Coronavirus therapy COVID-19 COVID-19 disease COVID-19 patient death drug effective drug ENhance expected homing IMPROVE intravenous lack literature review Mesenchymal stem cells microenvironment microRNA MSC MSCs multiple organ failure Patient patients promote reduce regenerative reported Research respiratory activity risk SARS-CoV-2 Sepsis STEM Stem cell therapy surgical syndrome therapy tissue repair Vaccine virus [DOI] 10.14336/AD.2020.0711 PMC 바로가기 [Article Type] Review Article
Mesenchymal Stem Cells and Their Extracellular Vesicles: A Potential Game Changer for the COVID-19 CrisisCell and Developmental Biology Published on 2020-09-302022-10-31 Journal: Frontiers in Cell and Developmental Biology [Category] COVID-19, [키워드] “cytokine storm” acute respiratory distress ARDS Corona virus COVID-19 COVID-19 patient COVID-19 patients crisis Cytokine storm death dependent on disease Effects ENhance Exosomes Extracellular vesicles game global public health help immune response immune system immunomodulation immunomodulatory effect immunomodulatory property IMPROVE induce infected patients Inflammatory response intervene kill lack mechanism Mesenchymal stem cells MSC MSCs Multi-organ damage organ outbreak outcome Patient Potential preventive measure PROTECT provide regulate responsible resulting SARS-CoV-2 severe cases severity of COVID-19 STEM stem cell syndrome the disease therapeutic tissue-repair Treatment turn virus [DOI] 10.3389/fcell.2020.587866 PMC 바로가기 [Article Type] Cell and Developmental Biology
The Potential Use of Mesenchymal Stem Cells and Their Derived Exosomes as Immunomodulatory Agents for COVID-19 PatientsReview Article Published on 2020-09-242022-10-29 Journal: Stem Cells International [Category] COVID-19, [키워드] acute respiratory disease acute respiratory distress acute respiratory syndrome adhere administration affected agent alveolar inflammation ARDS Bone marrow Cell cell-based therapies clinical trial coronavirus COVID-19 COVID-19 patient COVID-19 patients disease Efficacy epithelia example Exosome highlight lung injuries MSC MSCs pandemic pathological condition patients Pneumonia Potential Quality control respiratory tract risk SARS-CoV-2 shown significantly lower STEM stem cell stem cells Support syndrome therapeutic therapeutic potential therapy treating COVID-19 World Health Organization [DOI] 10.1155/2020/8835986 PMC 바로가기 [Article Type] Review Article
The use of mesenchymal stromal cells in the treatment of coronavirus disease 2019Review Published on 2020-09-212022-10-30 Journal: Journal of Translational Medicine [Category] COVID-19, SARS, [키워드] absence acute respiratory distress acute respiratory distress syndrome acute respiratory syndrome alleviate Antiviral ARDS arise changed clinical trial common condition coronavirus coronavirus disease Coronavirus infections Coronavirus-2 COVID-19 critically ill patients curtail death disease drug Effect Host host-response immune response immunomodulatory properties Infection intensive care Mesenchymal stromal cells Middle East MSC MSCs multiple sclerosis Osteoarthritis outbreak pandemic Patient potential treatments reduce regenerative Safe SARS-CoV-2 SARS-COV-2 infection Seven severity Spread stromal cell syndrome therapy Treatment Vaccine while [DOI] 10.1186/s12967-020-02532-4 PMC 바로가기 [Article Type] Review