Pulmonary Mesenchymal Stem Cells in Mild Cases of COVID-19 Are Dedicated to Proliferation; In Severe Cases, They Control Inflammation, Make Cell Dispersion, and Tissue RegenerationImmunology Published on 2022-01-132022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, [키워드] “cytokine storm” affected Alter Analysis biological function bronchoalveolar lavage sample CD40 Cell cell proliferation Cell therapy cell types chemotaxis clinical conditions Control COVID-19 COVID-19 patient Cytokine storm cytoplasmic Data analysis dispersion FHL2 Genes IFNGR1 IFNGR2 immune individual individuals induce inhibitor involved lung marker MDA5 mesenchymal stem cell Mild mild case mild COVID-19 patients MSC MSCs Necrosis NF-κB NFKBIA not express OPTN overexpression paracrine Patient performed PKR PPP2CB promote inflammation pulmonary receptors regeneration RNA secretion sequence Severe case severe COVID-19 single cell RNA sequencing single-cell RNA-seq STEM stem cell Target genes therapeutic therapeutic potential therapy for COVID-19 these cell tissue tlr-3 TLRs TNFR1 TNFR2 Transcription transcriptionally treat triggered upregulated upregulated gene upstream virus virus load [DOI] 10.3389/fimmu.2021.780900 PMC 바로가기 [Article Type] Immunology
Rapid, simplified whole blood-based multiparameter assay to quantify and phenotype SARS-CoV-2-specific T-cellsSARS-CoV-2-특이적 T 세포를 정량화하고 표현형을 지정하기 위한 신속하고 간소화된 전혈 기반 다중 매개변수 분석Article Published on 2022-01-132022-09-11 Journal: The European Respiratory Journal [Category] Fulltext, SARS, 진단, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 adaptive Adaptive immunity Blood CD4 CD4 T-cell Cell cells convalescent coronavirus COVID-19 detectable Differentiated cells evaluate flow cytometry granzyme healthcare worker IFN-γ Immunity indicated interferon memory MONITOR natural infection Necrosis participant Participants PCR-negative Peripheral blood phenotype protective immunity Rapid Rapid tests reported symptoms representing respiratory response SARS-CoV-2 severe acute respiratory syndrome Coronavirus Symptom T-cell T-cell Response T-cell responses T-cells tested trials tumour necrosis factor tumour necrosis factor-α Vaccine Vaccine-induced immunity Whole blood [DOI] 10.1183/13993003.00285-2021 PMC 바로가기 [Article Type] Article
Acute superior mesenteric artery occlusion associated with COVID-19 pneumonia: a case reportCase Report Published on 2022-01-102022-10-28 Journal: Surgical Case Reports [Category] COVID-19, [키워드] 2019 coronavirus disease abdominal pain activity acute respiratory syndrome addition Asia bowel Case report caused Colon Combination Contrast coronavirus cough COVID-19 daily living deaths demonstrated Diagnosis diarrhea distribution East exploratory ground glass hospital hypercoagulable IMPROVE independent induce Infarction Infection Intervention intestinal intestine intravenous Ischemia Local medical resource Moderate COVID-19 Necrosis necrotic occur Patient patients with COVID-19 performed physician Pneumonia positive postoperative postoperative course Prognosis rehabilitation renal returned SARS-CoV-2 Spread Superior mesenteric artery occlusion surgical Surgical Procedure the patient thrombosis treat treated Treatment treatment for COVID-19 was performed with COVID-19 worsening [DOI] 10.1186/s40792-022-01360-6 PMC 바로가기 [Article Type] Case Report
Pyoderma Gangrenosum Induced by BNT162b2 COVID-19 Vaccine in a Healthy AdultCase Report Published on 2022-01-072022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] adverse event BNT162b2 BNT162b2 vaccine characteristic continuous monitoring Coronavirus disease 2019 COVID-19 COVID-19 vaccine Cutaneous manifestations described develop edema epidermal etiology first dose hospital immunosuppressive induced infiltration Inflammation Inflammatory manifestation mRNA mRNA vaccine mRNA vaccines Necrosis neutrophilic Patient Pfizer/BioNTech pyoderma Pyoderma gangrenosum receiving skin skin lesion Surveillance therapy ulcerative Vaccine variety [DOI] 10.3390/vaccines10010087 PMC 바로가기 [Article Type] Case Report
An Imaging and Computational Algorithm for Efficient Identification and Quantification of Neutrophil Extracellular Traps호중구 세포외 트랩의 효율적인 식별 및 정량화를 위한 이미징 및 계산 알고리즘Article Published on 2022-01-062022-09-11 Journal: Cells [Category] SARS, 진단, 치료기술, 치료제, [키워드] acute respiratory distress acute respiratory distress syndrome Algorithm analyses Analysis Annexin Apoptosis approach Arthritis Asthma Cancer Cell cell death cellomics cells Combination COVID-19 death disease pathology DNA efficient eliminated ELISA ENhance exhibited extracellular trap fixation flow cytometry high content screening identification identify Image imaging immunoblotting impermeable inconsistency increase in Inflammation inhibitor intensities intensity lupus erythematosus Microscopy modulate morphology Multiple Necrosis NET NETosis NETs neutrophil Neutrophil extracellular traps Neutrophils nomenclature non-specific nuclear pathway platform provided quantification respiratory distress rheumatoid arthritis Sepsis single-cell single-cell analysis staining suffered syndrome systemic lupus erythematosus target Therapeutic approach therapeutic approaches [DOI] 10.3390/cells11020191 PMC 바로가기 [Article Type] Article
Pilot Study on the Impact of a Home-Based Exercise Program on Inflammatory Cytokines and Quality of Life in Men with Prostate Cancer Under Active SurveillanceArticle Published on 2022-01-012022-11-15 Journal: Cancer control : journal of the Moffitt Cancer Cen [Category] 바이오마커, [키워드] 6-minute walk test 6MWT 6MWT distance Active surveillance aerobic Alpha baseline Biomarker Biomarkers body mass index collected control group COVID-19 decrease emotional endothelial exercise Exercise intervention functional Future growth factor IL-12 IL-1α IL-5 IL-6 Impact increase in INF-γ Inflammatory biomarker Inflammatory cytokine interferon-γ interleukin-6 Intervention intervention group Isolation life marker men Necrosis parallel group physical Program Prostate Prostate cancer Quality Quality of life Randomized Significant significantly increased TNF-α translation tumor progression Vascular VEGF was used [DOI] 10.1177/10732748221130964 PMC 바로가기
A SARS-CoV-2 Delta Variant Case Manifesting as Extensive Placental Infection and Fetal TransmissionArticle Published on 2022-01-012022-11-15 Journal: Gynecologic and obstetric investigation [Category] SARS, 변종, 치료기술, [키워드] analyzed Apoptosis B.1.167.2 Cell COVID-19 Delta delta variant determine dominant exhibited Extensive Ferroptosis fetal fixed higher infectivity Infection membrane membranes mother Mutation Necrosis Placenta placental Placental infection placental tissue positive Pregnancy Premature Probability receptor-binding motif rupture SAR-CoV-2 SARS-CoV-2 SARS-CoV-2 detection SARS-COV-2 infection Spike protein tested Transmission umbilical variant Vascular endothelium vertical transmission Viral RNA with COVID-19 [DOI] 10.1159/000524905 PMC 바로가기
Endodontics Specialists’ Practice during the Initial Outbreak of Coronavirus Disease 2019Observational Study Published on 2022-01-012022-10-05 Journal: Journal of endodontics [Category] SARS, 임상, [키워드] 95% CI 95% confidence interval Analysis Apical Periodontitis Asymptomatic characteristics of patient collected coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 outbreak demographic diagnose diagnosed diagnostic disease Endodontics Health Infection initial initiated Kidney disease less Logistic regression management multiple logistic regression Necrosis Odds ratio older patient oral systemic disease outbreak Pain Patient Practice practice management public health root canal specialist the United State Treatment variables were used [DOI] 10.1016/j.joen.2021.09.015 PMC 바로가기 [Article Type] Observational Study
Stillbirth and fetal capillary infection by SARS-CoV-2SARS-CoV-2에 의한 사산 및 태아 모세관 감염Article Published on 2022-01-012022-09-11 Journal: American journal of obstetrics & gynecology MFM [Category] SARS, 치료기술, 치료제, [키워드] affected can not Capillaries capillary Cell cell type Chain Reaction consequence COVID-19 cytoplasm electron microscopy electron microscopy image Endothelial cell endothelial cells fetal FIBRIN gross examination Hemorrhagic Infarction Infection intravillous involved Ischemia Ischemic necrosis lesion luminal Microscopy mother Multiple Necrosis Occurrence Particle Placenta placental tissue Platelet polymerase chain reaction predicted real-time reverse transcription-polymerase chain reaction reported SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 RNA Stillbirth subsequent Surveillance synchronous syncytiotrophoblast target cell thrombosis Transmission triggered Vascular vertical transmission vessel virus particles with infection [DOI] 10.1016/j.ajogmf.2021.100523 PMC 바로가기 [Article Type] Article
Postmortem Biopsies of the Lung, Heart, Liver, and Spleen of COVID-19 PatientsRadiology Published on 2021-12-272022-10-31 Journal: Cureus [Category] COVID-19, [키워드] acquisition alteration autopsy studies biopsies biopsy Case series Characteristics Chest computed tomography collected Complete coronavirus disease correlated COVID-19 died Diffuse alveolar damage evaluate examined feasible FIVE Ground-glass opacities heart heart tissue histopathologic histopathological infiltration liver lung lung biopsy Lungs material Microscope mononuclear cell Necrosis neutrophil infiltration nonspecific objective Patient patients performed Postmortem Result SARS-CoV-2 specimens spleen spleen tissue Splenic steatosis the patient tissue Treatment underlying disease were stained [DOI] 10.7759/cureus.20734 PMC 바로가기 [Article Type] Radiology