Neutrophil to Lymphocyte Ratio: An Emerging Marker of the Relationships between the Immune System and Diseases호중구 대 림프구 비율: 면역 체계와 질병 간의 관계에 대한 새로운 지표Review Published on 2022-03-262022-09-11 Journal: International Journal of Molecular Sciences [Category] MERS, 바이오마커, [키워드] adaptive Adaptive immunity Biomarker Cancer concerning coronavirus coronavirus disease coronavirus disease-2019 coronavirus disease-2019 (COVID-19) COVID-19 COVID-19 pneumonia cut-off value disease FLAG General population homeostasis immune system Immunity inflammatory status intensive care intensive care unit intensive care unit (ICU) lymphocyte marker molecular basis Mortality neutrophil Neutrophil-to-lymphocyte ratio neutrophil-to-lymphocyte ratio (NLR) NLR over pathophysiology patients with COVID-19 Pneumonia Prognosis Prognostic value relationship Research Sepsis subset System unique [DOI] 10.3390/ijms23073636 PMC 바로가기 [Article Type] Review
Evaluation of science advice during the COVID-19 pandemic in Sweden Research Published on 2022-03-222022-10-05 Journal: Humanities & Social Sciences Communications [Category] 치료법, [키워드] acting Administered approach asymptomatic individual contagious Control COVID-19 COVID-19 pandemic Culture death rate evaluate Evidence extreme Face mask independent International Karolinska Institute lack media methodology National Norway occurred over oxygen pandemic pandemic of COVID-19 Pandemics Prevent PROTECT Public recommendation responsible resulting SARS-CoV-2 transmission Scientific community Swedish [DOI] 10.1057/s41599-022-01097-5 [Article Type] Research
Associations of statin use with 30-day adverse outcomes among 4 801 406 US Veterans with and without SARS-CoV-2: an observational cohort studyObservational Study Published on 2022-03-182022-10-05 Journal: BMJ Open [Category] SARS, 임상, [키워드] 95% CI Admission adverse outcome association cohort study Comparator group Control controls COVID-19 death Epidemiology examined healthcare hospitalisation ICU ICU admission individual intensity intensive care Interaction internal medicine lab Mortality nasal swab Observational cohort study outcome over performed positive Positive test receiving SARS-CoV-2 significantly specific effects tested veteran [DOI] 10.1136/bmjopen-2021-058363 PMC 바로가기 [Article Type] Observational Study
Identification of Genetic Risk Factors of Severe COVID-19 Using Extensive Phenotypic Data: A Proof-of-Concept Study in a Cohort of Russian Patients광범위한 표현형 데이터를 사용한 심각한 COVID-19의 유전적 위험 요인 식별: 러시아 환자 집단에서 개념 증명 연구Article Published on 2022-03-172022-09-11 Journal: Genes [Category] 변종, [키워드] Analysis association ATXN1 binary trait breadth candidate gene CDH23 circumvent Cohort cohort of patients cohorts conducted COVID-19 COVID-19 pandemic COVID-19 patient COVID-19 patients COVID-19 severity deep phenotyping disease severity Extensive Factor Genetic genetic associations genetic risk factor genetic risk factors Genetic variant genetic variants genome coverage genomes GWAS Hospitalization Host identification identify independent Interaction loci MYH14 NGS outcome over pathogen predict Quantitative quantitative trait quantitative traits replicated researcher risk Russia SCN11A SETX severe COVID-19 severity the disease UK Biobank data utility variant variants variety while [DOI] 10.3390/genes13030534 PMC 바로가기 [Article Type] Article
Clinical Evaluation of a Fully-Automated High-Throughput Multiplex Screening-Assay to Detect and Differentiate the SARS-CoV-2 B.1.1.529 (Omicron) and B.1.617.2 (Delta) Lineage VariantsSARS-CoV-2 B.1.1.529(오미크론) 및 B.1.617.2(델타) 계통 변이체를 감지하고 구별하기 위한 완전 자동화된 고처리량 멀티플렉스 스크리닝 분석의 임상 평가Article Published on 2022-03-152022-09-11 Journal: Viruses [Category] SARS, 변종, 치료기술, 치료제, [키워드] amplification B.1.1.529 B.1.617.2 can be used Cell culture cell culture supernatant circulating clinical clinical samples Delta delta variant discrimination evaluated Healthcare system Healthcare systems high risk immunized large sample Lineage monoclonal antibody multiplex Multiplex assay NGS no interaction normalized omicron Omicron variant over P681H P681R patient treatment Population positive sample Primers probe probes public health measures qPCR RT-PCR RT-qPCR SARS-CoV-2 sensitivity sequence sequence variation Sequencing Spread target the SARS-CoV-2 Therapies variant variant screening variants of concern VoC VOCs was determined whole genome Whole genome sequencing [DOI] 10.3390/v14030608 PMC 바로가기 [Article Type] Article
Monitoring the impact of COVID-19 in France on cancer care: a differentiated impactArticle Published on 2022-03-102022-10-04 Journal: Scientific Reports [Category] MERS, 치료기술, 치료법, [키워드] activity Cancer Care Chemotherapy conducted conserved COVID-19 COVID-19 pandemic database diagnostic digestive France French Health Health care healthcare individual limit lockdown medium MONITOR monitoring oncology over patients Radiotherapy remains uncertain returned Safeguarding surgical survival therapeutic activity [DOI] 10.1038/s41598-022-07984-w PMC 바로가기 [Article Type] Article
Severe Post-COVID-19 dysautonomia: a case reportCase Report Published on 2022-03-032022-10-28 Journal: BMC Infectious Diseases [Category] COVID-19, MERS, SARS, [키워드] activity acute respiratory syndrome Anxiety autonomic blood pressure body aches Brain Case report Cognitive impairment coronavirus COVID-19 COVID-19 infection daily living develop Dysautonomia dysfunction Effect Evidence fatigue FIVE headache Headaches healthy help include increasingly infection with COVID-19 initial Insomnia Laboratory Mild orthostatic over pathophysiology Patient Post-acute sequalae of COVID-19 (PASC) Postural orthostatic tachycardia syndrome (POTS) prevalent progressed Research seated sodium sweating Symptom Symptoms Tachycardia the patient Treatment Variability weakness [DOI] 10.1186/s12879-022-07181-0 PMC 바로가기 [Article Type] Case Report
Immune Responses to the ChAdOx1 nCoV-19 and BNT162b2 Vaccines and to Natural Coronavirus Disease 2019 Infections Over a 3-Month Period3개월 동안의 ChAdOx1 nCoV-19 및 BNT162b2 백신과 2019년 천연 코로나바이러스 감염에 대한 면역 반응Article Published on 2022-03-022022-09-12 Journal: The Journal of Infectious Diseases [Category] MERS, SARS, 진단, [키워드] analyzed antibody Antibody Response BNT162b2 BNT162b2 vaccine ChAdOx1 ChAdOx1 nCoV-19 ChAdOx1 nCoV-19 vaccine ChAdOx1 vaccine coronavirus disease COVID-19 enrolled healthcare worker IgG immune response Immunoglobulin infections natural natural infection neutralizing antibody Neutralizing antibody titer of BNT162b2 over Patient Period response S1 IgG second dose second dose. significantly T cells T-cell Response T-cell responses Vaccine vaccinee vaccinees [DOI] 10.1093/infdis/jiab579 PMC 바로가기 [Article Type] Article
Evaluation of a rapid-antigen test for COVID-19 in an asymptomatic collective : A prospective study무증상 집단에서의 코로나19 신속항원검사 평가 : 전향적 연구Article Published on 2022-03-012022-09-11 Journal: Wiener medizinische Wochenschrift (1946) [Category] SARS, 치료기술, [키워드] Antigen antigen detection Asymptomatic average carried Chain Reaction confidence interval COVID-19 COVID-19 patient COVID-19 patients cycle threshold District early stage early stages evaluate hospital mass Mass screening over performed point of care point-of-care testing polymerase chain polymerase chain reaction positive positive result Prospective Study Rapid Rapid antigen tests Real-Time Reverse Transcription Polymerase Chain Reaction Real-time reverse transcription polymerase chain reaction. resource reverse transcription reverse transcription polymerase chain reaction Roche Diagnostics RT-PCR RT-PCR tests SARS-CoV‑2 sensitivity Sensitivity and specificity significant increase specificity Swab Symptom tested the mean treated Viral load viral loads was done [DOI] 10.1007/s10354-021-00883-1 PMC 바로가기 [Article Type] Article
Computational investigation reveals that the mutant strains of SARS-CoV2 have differential structural and binding properties전산 조사에 따르면 SARS-CoV2의 돌연변이 균주는 차등적인 구조 및 결합 특성을 가지고 있습니다Article Published on 2022-03-012022-09-11 Journal: Computer methods and programs in biomedicine [Category] SARS, 변종, 유전자 메커니즘, [키워드] approaches binding binding affinity caused computational method Computational methods Course docking exhibited functional genetic variants host protein Infection manifested MD simulation mechanism molecular molecular basis molecular dynamics mutant mutant strain Mutant strains network network analysis over pandemic Pathogenesis persistent infection Protein protein structure protein-protein interaction RBD Receptor binding domain reveal SARS-CoV2 Scientific community Severe acute respiratory syndrome strain Structure Transmission utility V367F V483A variant variants virus wildtype [DOI] 10.1016/j.cmpb.2021.106594 PMC 바로가기 [Article Type] Article