SARS-CoV-2 Genome-Based Severity Predictions Correspond to Lower qPCR Values and Higher Viral LoadSARS-CoV-2 게놈 기반 심각도 예측은 더 낮은 qPCR 값 및 더 높은 바이러스 부하에 해당Article Published on 2022-05-312022-09-11 Journal: Global health, epidemiology and genomics [Category] COVID19(2023년), SARS, 변종, [키워드] 2019 coronavirus disease Algorithm average Clinical severity clinically coronavirus disease correlation COVID-19 cycle threshold demonstrated diagnostic diagnostic test evaluate global pandemic identifying load Lower Mutation pandemic PCR predicted prediction Predictive Probability qPCR quartiles resulting SARS-CoV-2 several variant several variants severity surpassed surrogate Transmissibility value viral genome viral genomes Viral load [DOI] 10.1155/2022/6499217 PMC 바로가기 [Article Type] Article
CMV seropositivity is a potential novel risk factor for severe COVID-19 in non-geriatric patientsCMV 혈청 양성은 비노인 환자에서 심각한 COVID-19에 대한 잠재적인 새로운 위험 요소입니다Article Published on 2022-05-252022-09-11 Journal: PLoS ONE [Category] COVID19(2023년), MERS, SARS, 변종, 진단, 치료기술, [키워드] absence advanced age affected Analysis Biomarker CMV co-morbidities Cohort cohorts Comorbidities confirmation COVID-19 Critical cross-reactivity cytomegalovirus deaths detectable disease disease severity distribution finding herpes simplex herpes simplex virus higher risk Hypothesis ICU IgG individual individuals intensive care investigated Mild Mild disease moderate morbidities occur older patients Patient performed prediction Prevalence representing risk factor SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants serology Seropositivity serostatus severe COVID-19 severe disease statistical Support T cell T cells were used with mild disease [DOI] 10.1371/journal.pone.0268530 PMC 바로가기 [Article Type] Article
Development and evaluation of a machine learning-based in-hospital COVID-19 disease outcome predictor (CODOP): A multicontinental retrospective study기계 학습 기반 병원 내 COVID-19 질병 결과 예측기(CODOP) 개발 및 평가: 다대륙 후향적 연구Article Published on 2022-05-172022-09-11 Journal: eLife [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] allocation AUROC breakthrough infections calibrated Clinical outcome clinical parameter clinical utility clinically Cohort cohort of patient Computational biology country COVID-19 COVID-19 disease COVID-19 patient deaths development disperse effective heterogeneous hospital Hospital admission hospital resources Hospitalization hospitalizations hospitalized COVID-19 patients Human In-hospital Latin Latin America machine-learning maintain Medicine New offer outcome pandemic patient cohort patient cohorts prediction Predictive Retrospective study risk stratification SARS-CoV-2 variants sensitivity Spain specificity Systems biology tested Triage USA vaccination vaccination rate Vaccination Status variant virus waning immunity [DOI] 10.7554/eLife.75985 PMC 바로가기 [Article Type] Article
Human-to-dog transmission of SARS-CoV-2, Colombia콜롬비아, SARS-CoV-2의 사람에서 개 전염Article Published on 2022-05-122022-09-11 Journal: Scientific Reports [Category] COVID19(2023년), SARS, 변종, 치료제, [키워드] ACE2 protein acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 causative agent clade close contact Complete conservation contribute coronavirus 2 COVID-19 pandemic docking E484K E484K mutation events Genome help hosts Human Latin America Lineage Localization molecular analysis Mutation non-human primates Phylogenetic prediction Prevent Protein protein structure public health RBD receptor Receptor-binding domain respiratory SARS-CoV-2 sequenced Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus Spike protein symptomatic the receptor-binding domain the Spike Transmission transmission of SARS-CoV-2 viral infection viral sequence viral sequences virus [DOI] 10.1038/s41598-022-11847-9 PMC 바로가기 [Article Type] Article
A Robust Framework for Epidemic Analysis, Prediction and Detection of COVID-19COVID-19의 전염병 분석, 예측 및 탐지를 위한 강력한 프레임워크Article Published on 2022-05-062022-09-11 Journal: Frontiers in Public Health [Category] COVID19(2023년), SARS, 치료기술, [키워드] Accuracy Affect Analysis center central limit theorem Chain Reaction circulation composed Coronavirus - COVID-19 country COVID COVID case COVID cases COVID-19 COVID-19 disease COVID-19 infection dataset detect detection disease disease control distribution doubling dry cough Epidemic epidemic spreading algorithm estimate estimation Evolution extreme False-positive feature Features feeble Fever flu Frame framework gaussian gaussian distribution generate Gradient histogram immune systems India individual Infection infections Infectious disease Italy Johns Hopkin Johns Hopkins limit lung mandatory mathematical mathematical model outcome pandemic parameter parameters polymerase chain polymerase chain reaction predict prediction Prevent real-time polymerase chain reaction regulated robust RT-PCR Saudi Arabia scale Spread statistical Symptom the disease thickness time evolution Time-series (TS) model Viral pneumonia widespread [DOI] 10.3389/fpubh.2022.805086 PMC 바로가기 [Article Type] Article
Fast and Effective Prediction of the Absolute Binding Free Energies of Covalent Inhibitors of SARS-CoV-2 Main Protease and 20S ProteasomeSARS-CoV-2 주요 프로테아제 및 20S 프로테아좀의 공유 억제제의 절대 결합 자유 에너지의 빠르고 효과적인 예측Article Published on 2022-05-042022-09-11 Journal: Journal of the American Chemical Society [Category] COVID19(2023년), SARS, 변종, 치료제, [키워드] accelerated activities Amino acid applicability approach binding affinities binding affinity binding free energy cause computational method covalent bond COVID-19 COVID-19 pandemic Degradation drug Effect effective electrophilic energetics energy enzyme evaluate exploration Free globe inhibitor inhibitors inhibitors of SARS-CoV-2 interactions M pro modulation powerful tool prediction protease proteasome Protein protocol public health emergency reaction reservation robust SARS-CoV-2 shown significantly target Therapeutic strategies variant warhead water [DOI] 10.1021/jacs.2c00853 PMC 바로가기 [Article Type] Article
In Silico Prediction of New Mutations That Can Improve the Binding Abilities Between 2019-nCoV Coronavirus and Human ACE22019-nCoV 코로나바이러스와 인간 ACE2 간의 결합 능력을 향상시킬 수 있는 새로운 돌연변이의 실리코 예측Article Published on 2022-05-012022-09-11 Journal: IEEE/ACM transactions on computational biology and [Category] COVID19(2023년), SARS, 변종, 유전자 메커니즘, 치료기술, [키워드] 2019-nCoV Ability ACE2 Amino acid Analysis binding binding ability binding free energies binding free energy calculate Can change conducted coronavirus coronavirus disease Coronavirus disease 2019 coronavirus spike protein COVID-19 drug drug and vaccine development dynamic ENhance Epidemic Health help Human human ACE2 IMPROVE Interaction international public health mechanism molecular dynamic simulations mutant Mutation mutations nCoV New pathogenic prediction Protein Research selected Simulation Spike protein susceptible The 2019-nCoV Vaccine development virus transmission was obtained [DOI] 10.1109/TCBB.2021.3058265 PMC 바로가기 [Article Type] Article
Socio-demographic, lifestyle and health characteristics as predictors of self-reported Covid-19 history among older adults: 2006-2020 Health and Retirement StudyResearch article Published on 2022-05-012022-10-05 Journal: American journal of infection control [Category] 바이오마커, [키워드] Adults Analysis analyzed blood pressure cardiometabolic cardiometabolic risk factor Characteristics chronic condition coronavirus coronavirus disease depressive symptom Epidemiology female group Health Hispanic ethnicity identify Logistic Logistic regression logistic regression models Longitudinal data number of household Older Older adults physical activity prediction predictor preliminary findings Result retirement Sex socio-demographic statistically significant trajectory United State [DOI] 10.1016/j.ajic.2022.02.021 [Article Type] Research article
On the prediction of isolation, release, and decease states for COVID-19 patients: A case study in South KoreaArticle Published on 2022-05-012023-07-06 Journal: ISA transactions [Category] COVID19(2023년), [키워드] classification COVID-19 Decease Decision tree Isolation multinomial logistic regression prediction Random forest Release [DOI] 10.1016/j.isatra.2020.12.053 PMC 바로가기
Linear and non-linear dynamics of the epidemics: System identification based parametric prediction models for the pandemic outbreaksArticle Published on 2022-05-012023-07-06 Journal: ISA transactions [Category] COVID19(2023년), [키워드] Casualties COVID-19 Linear dynamics Model non-linear dynamics pandemic prediction [DOI] 10.1016/j.isatra.2021.08.008 PMC 바로가기