Predicting the recombination potential of severe acute respiratory syndrome coronavirus 2 and Middle East respiratory syndrome coronavirusResearch Article Published on 2020-12-092022-10-30 Journal: The Journal of General Virology [Category] COVID-19, SARS, [키워드] ACE2 acute respiratory syndrome analysed analyses anatomical cause cellular receptor co-expression Co-infection coronavirus develop diagnostic DPP4 emergence facilitate Fatality rate genomic region high-risk area homologous humans identify Infection interacting residues investigated Kingdom Laboratory MERS-CoV MERS-CoV RNA Middle East ORF1ab outbreak Patient predictions public health Recombination recombination event reported respiratory syndrome coronavirus S gene SARS-CoV-2 SARS-COV-2 infection Saudi Arabia susceptibility Virus spike widespread [DOI] 10.1099/jgv.0.001491 PMC 바로가기 [Article Type] Research Article
Deletion in the S1 Region of Porcine Epidemic Diarrhea Virus Reduces the Virulence and Influences the Virus-Neutralizing Activity of the Antibody InducedArticle Published on 2020-12-022022-10-28 Journal: Viruses [Category] Coronavirus, MERS, [키워드] activity Amino acid antibody antigenicity cause caused Clinical sign Complete cross-neutralize Deletion diarrhea distribution domain Epidemic epidemic diarrhea Genome induced induces influence lower mortality Mortality neutralizing active occurred PEDV reduce Region S gene spike gene Spike protein Strains variant virulence virus virus-neutralizing [DOI] 10.3390/v12121378 PMC 바로가기 [Article Type] Article
First proof of the capability of wastewater surveillance for COVID-19 in India through detection of genetic material of SARS-CoV-2Short communication Published on 2020-12-012022-10-05 Journal: The Science of the total environment [Category] SARS, 치료기술, [키워드] aquatic environment assist carried change changes in China collected comparable Concentration coronavirus COVID-19 COVID-19 pandemic COVID-19 patient detect effort Environmental surveillance Epidemiology explicit France Genetic genetic material Gujarat increase increase in India ORF1ab pandemic Pandemic monitoring Perspective plant receive reported S gene sampling SARS-CoV-2 SARS-CoV-2 RNA SARS-CoV-2 virus Spain Surveillance treating COVID-19 patients Turkey USA waste wastewater based epidemiology water while [DOI] 10.1016/j.scitotenv.2020.141326 [Article Type] Short communication
In-silico nucleotide and protein analyses of S-gene region in selected zoonotic coronaviruses reveal conserved domains and evolutionary emergence with trajectory course of viral entry from SARS-CoV-2 genomic data선택된 동물성 코로나바이러스에서 S-유전자 영역의 인-실리코 뉴클레오티드 및 단백질 분석은 SARS-CoV-2 게놈 데이터에서 바이러스 진입의 궤적 과정과 함께 보존된 도메인 및 진화적 출현을 나타냅니다Research Published on 2020-11-302022-09-10 Journal: The Pan African Medical Journal [Category] Fulltext, MERS, SARS, 유전자 메커니즘, 조류인플루엔자, [키워드] 229E Affect Analysis analyzed ancestors antagonistic action Antiviral cellular mechanism clades conserved conserved domains coronavirus Course COVID-19 dating domain domains effective Evolution FIVE genomic genomic data Host host cells human coronavirus human population human populations include management Migration Multiple sequence alignment multiple sequence alignments Mutation nucleotide outbreak Outbreaks pandemic pathway Phylogeny Population Profiling Protein Racial respiratory Respiratory Coronavirus Result S gene S-gene SARS-CoV-2 SARS-CoV-2 genomic data SARS-CoV-2 phylogeny selected sequence alignments severe acute respiratory coronavirus spike gene target the SARS-CoV-2 therapeutic trajectory Viral viral entry virus viruses Wuhan zoonotic Zoonotic coronavirus zoonotic coronaviruses zoonotic CoVs [DOI] 10.11604/pamj.2020.37.285.24663 PMC 바로가기 [Article Type] Research
Nucleic acid amplification tests on respiratory samples for the diagnosis of coronavirus infections: a systematic review and meta-analysisSystematic Review Published on 2020-11-112022-11-01 Journal: Clinical microbiology and infection : the official [Category] COVID-19, SARS, [키워드] Accuracy acute respiratory syndrome acute respiratory tract infection affecting amplification assessment average can be used clinical samples Cochrane Library confidence coronavirus coronavirus disease Coronavirus infection Coronavirus infections COVID-19 defined diagnosed Diagnosis diagnostic eligibility eligible evaluate evaluated Grey high risk isothermal amplification Lower respiratory tract Meta-analysis meta-regression NAAT nucleic acid amplification nucleic acid amplification tests objective participant Patient PCR PCR assay PCR tests pooling Quality RdRP real-time RT-PCR reference reference standard Region reported respiratory sample Result RNA-dependent RNA polymerase RT-LAMP S gene SARS-CoV-2 sensitivity Sensitivity and specificity significantly higher significantly lower specificity systematic review transcriptase variable Web of Science [DOI] 10.1016/j.cmi.2020.11.002 PMC 바로가기 [Article Type] Systematic Review
The novel coronavirus SARS-CoV-2: From a zoonotic infection to coronavirus disease 2019신종 코로나바이러스 SARS-CoV-2: 인수공통전염병에서 코로나바이러스 질병 2019까지Article Published on 2020-11-012022-09-11 Journal: Journal of medical virology [Category] SARS, 변종, 유전자 메커니즘, 조류인플루엔자, [키워드] acute respiratory syndrome adaptation Analysis animals bat coronaviruses carried Chinese Cluster Complete coronavirus disease correlated CoV CoV genome demonstrated facilitate Genome genomic region Host hosts Human human cells human host Infection intermediate host intermediate hosts international public health isolate mechanism Modification Mutation Novel coronavirus pangolin pangolin CoV pangolins Phylogenetic Phylogenetic analysis Phylogenetic tree Phylogeny Protein RaTG13 reconstructed respiratory S gene S protein SARS-CoV-2 Severe acute respiratory syndrome strain Strains Substitution suggested the S protein virus was performed zoonotic zoonotic infection [DOI] 10.1002/jmv.26072 PMC 바로가기 [Article Type] Article
A Founder Effect Led Early SARS-CoV-2 Transmission in Spain스페인에서 초기 SARS-CoV-2 전파를 주도한 파운더 효과Genetic Diversity and Evolution Published on 2020-10-302022-09-10 Journal: Journal of Virology [Category] MERS, 변종, 유전자 메커니즘, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus analyses Analysis Bayesian characterized clade clades Cluster coronavirus country COVID-19 COVID-19 case D614 variant D614G D614G substitution diffusion displaying dissemination Effect Europe European country explosion FIVE founder effect higher infectivity independent majority maximum-likelihood MOST Multiple occurred ORF8 pandemic phylodynamic phylodynamics Phylogenetic phylogenetic analyses phylogeography Prevalence prevalent pseudotyped virion pseudotyped virions Region replaced REPLACED BY respiratory S gene SARS-CoV-2 SARS-CoV-2 pandemic SARS-CoV-2 spike protein sequence sequences severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 Spain Spike protein the epidemic the SARS-CoV-2 the spike protein transmitted variant virus viruses whole-genome Whole-genome sequence Wuhan Wuhan, China [DOI] 10.1128/JVI.01583-20 PMC 바로가기 [Article Type] Genetic Diversity and Evolution
Re-emergence of porcine epidemic diarrhea virus in a piglet-producing farm in northwestern Germany in 2019Case Report Published on 2020-09-102022-10-28 Journal: BMC veterinary research [Category] Coronavirus, [키워드] addition Affect affected age Analysis analyzed Asia Case report change circulating Cluster country disease England epidemic diarrhea Europe European country fecal France Genetic Germany Hungary identity initial investigated less metagenomic metagenomics Next-generation sequencing outbreak PEDV Phylogenetic analysis Picobirnavirus porcine epidemic diarrhea virus (PEDV) real-time RT-PCR Relevance reported S gene sequence small intestine Spread strain the disease the spike protein the United State virulent virus while [DOI] 10.1186/s12917-020-02548-4 PMC 바로가기 [Article Type] Case Report
Genetic variations in S gene of porcine epidemic diarrhoea virus from 2018 in Sichuan Province, ChinaOriginal Article Published on 2020-09-042022-10-28 Journal: Veterinary medicine and science [Category] Coronavirus, [키워드] Amino acid amino acid insertion amino acid sequence amplified Analysis China COE coronavirus Deletion diarrhoea disease downloaded Epidemic epitope Evolution GenBank Genetic Genetic evolution genogroup indicated intestinal Laboratory Mutation pathogen PEDV Phylogenetic analysis Prevalence Research S gene S protein sequence Spread strain the S protein Variation virus [DOI] 10.1002/vms3.326 PMC 바로가기 [Article Type] Original Article
Evaluation of three commercial assays for SARS-CoV-2 molecular detection in upper respiratory tract samples상기도 샘플에서 SARS-CoV-2 분자 검출을 위한 3가지 상용 분석 평가Comparative Study Published on 2020-09-042022-09-10 Journal: European Journal of Clinical Microbiology & Infect [Category] MERS, SARS, 진단, 치료기술, [키워드] 2019-nCoV 2019-nCoV assay Accuracy association Clinical practice comparable Consensus COVID-19 criterion diagnostic Diagnostic accuracy Direct eight False negative introduced molecular Molecular assay N gene ORF1ab gene patients with COVID-19 PCR performed positive positive sample quantified RdRP RdRp gene reference standard respiratory Respiratory samples respiratory tract samples RT-PCR S gene SARS-CoV-2 SARS-CoV-2 RNA detection Seven strength supplementary material swab sample upper respiratory tract Viral viral RNA load widespread [DOI] 10.1007/s10096-020-04025-0 PMC 바로가기 [Article Type] Comparative Study