supportive care – Page 11 – Communicable Diseases Research

A two-arm, randomized, controlled, multi-centric, open-label phase-2 study to evaluate the efficacy and safety of Itolizumab in moderate to severe ARDS patients due to COVID-19

COVID-19로 인한 중등도에서 중증 ARDS 환자에서 이톨리주맙의 효능과 안전성을 평가하기 위한 2군, 무작위, 대조, 다중 중심, 공개 라벨 2상 연구

Clinical Trial

Published on 2021-05-012022-09-12
Journal: Expert opinion on biological therapy [Category] MERS, SARS, 임상, 진단,

[키워드] 95% CI acute respiratory distress acute respiratory distress syndrome anti-CD6 ARDS Complete coronavirus COVID-19 COVID-19 patient COVID-19 patients cytokine release Cytokine release syndrome death effective Efficacy and safety Enrollment evaluate evaluated events FiO2 FIVE IL-6 immune immune hyperactivation immunomodulatory immunomodulatory therapy Immunotherapy itolizumab lymphopenia mAb moderate necrotic objective Open-label outcome PaO2 Patient patients Randomized reaction receiving reduction in reduction in mortality replaced reported Result Safe screened severe ARDS SpO2 supportive care survival syndrome Transient treated Treatment Two patient Two-arm
[DOI] 10.1080/14712598.2021.1905794 PMC 바로가기 [Article Type] Clinical Trial

Multiple system inflammatory syndrome associated with SARS-CoV-2 infection in an adult and an adolescent

성인 및 청소년의 SARS-CoV-2 감염과 관련된 다계통 염증 증후군

Case Reports

Published on 2021-05-012022-09-12
Journal: Rheumatology International [Category] SARS, 진단,

Therapeutic Potentials of Antiviral Plants Used in Traditional African Medicine With COVID-19 in Focus: A Nigerian Perspective

Pharmacology

Published on 2021-04-262022-10-31
Journal: Frontiers in Pharmacology [Category] COVID-19,

[키워드] 2019-nCoV acute respiratory syndrome addition adopted African anti-SARS-CoV-2 Antiviral antiviral drug approach available data carried caused Chinese Combination Community coronavirus coronavirus disease country COVID-19 drug Drug discovery effort Evidence global public health herb-drug interaction herbal immuno-stimulants in silico In vitro assay in vivo experiment increasingly information Interaction Intervention knowledge lethal disease management Medicine non-specific pandemic Phytomedicines plant Potential preventive measures provided recorded reported Research Respiratory disease risk SARS-CoV-2 supportive care TAM Traditional Traditional African Medicine Treatment Vaccines World War II
[DOI] 10.3389/fphar.2021.596855 PMC 바로가기 [Article Type] Pharmacology

Posterior Reversible Leukoencephalopathy Syndrome in a Patient after Acute COVID-19 Infection

Case Report

Published on 2021-04-232022-10-31
Journal: Case Reports in Neurological Medicine [Category] COVID-19,

The Society for Integrative Oncology Practice Recommendations for online consultation and treatment during the COVID-19 pandemic

Special Article

Published on 2021-04-142022-10-28
Journal: Supportive Care in Cancer [Category] Coronavirus, MERS, SARS,

Newly Diagnosed Acute Myeloid Leukemia in a Patient With Severe SARS-CoV-2 Infection

Infectious Disease

Published on 2021-04-142022-10-31
Journal: Cureus [Category] COVID-19,

Mortality Benefit of Convalescent Plasma in COVID-19: A Systematic Review and Meta-Analysis

Medicine

Published on 2021-04-092022-10-31
Journal: Frontiers in Medicine [Category] COVID-19,

[키워드] 95% CI 95% confidence interval adverse event Analysis article benefit Care classical Clinical symptoms clinically concomitant treatment conducted convalescent convalescent plasma COVID-19 COVID-19 patient defined discharge drugs effective Efficacy and safety Evidence exploratory study Future Health heterogeneity highest hospital Intervention lower mortality Meta-analysis Mortality mortality rate nine observational study outcomes Patient patients patients died patients treated plasma plasma therapy Primary outcome quantitative synthesis Randomized controlled trial RCTs receive reduced researcher review SARS-CoV 2 secondary outcome sensitivity analysis significantly lower statistical statistically significant reduction Steroids subgroup analysis supportive care Systemic review systemic review and meta-analysis the timing therapeutic option therapy Treatment
[DOI] 10.3389/fmed.2021.624924 PMC 바로가기 [Article Type] Medicine

Convalescent Plasma for the Prevention and Treatment of COVID-19: A Systematic Review and Quantitative Analysis

Review

Published on 2021-04-072022-10-31
Journal: JMIR Public Health and Surveillance [Category] COVID-19, MERS,

[키워드] administration adverse events antibodies antibody Antibody titers Antiviral antiviral activity articles benefit Case report Case series Case-control caused Clinical studies clinical study conducted convalescent plasma COVID-19 COVID-19 infection COVID-19 pandemic CP antibody criteria Critically ill data extraction demographics directive Donor dose effective Efficacy eligible Evidence Future generate Guidance heterogeneity identify immunology Immunotherapy in vitro incidence independent item knowledge literature mechanically ventilated Meta-analysis MOST nonrandomized Novel coronavirus objective offer Patient patients with COVID-19 performed plasma poor quality prevention Prophylactic protocols Quality Quantitative Quantitative analysis random-effects model Randomized controlled trial RCT RCTs recommendation reduce mortality reported Reporting Research Result review robust SARS-CoV-2 screening process searched Spread Support supportive care systematic review therapeutic Therapeutic treatment therapy therapy for COVID-19 Treatment viral clearance virus Web of Science
[DOI] 10.2196/25500 PMC 바로가기 [Article Type] Review

COVID-19 Mortality Rates Among Nursing Home Residents Declined From March To November 2020

2020년 3월부터 11월까지 요양원 거주자의 COVID-19 사망률 감소

Article

Published on 2021-04-012022-09-11
Journal: Health affairs (Project Hope) [Category] 유전자 메커니즘,

Precision therapeutic targets for COVID-19

COVID-19에 대한 정밀 치료 표적

Review

Published on 2021-03-292022-09-10
Journal: Virology Journal [Category] SARS, 치료제,

[키워드] acute respiratory distress acute respiratory distress syndrome acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Administered antiviral drug antiviral drugs approved benefit caused convalescent plasma coronavirus coronavirus disease Coronavirus disease 2019 cough COVID-19 deaths demonstrated develop Dexamethasone disease domains drug drugs Dyspnea Effect Efficacy evaluate fatigue Fever General population Glucocorticoids High-dose Hospitalization hospitalized patients hypercoagulability individual infected with SARS-CoV-2 inhibiting less limitation M pro M^Pro main protease management multi-organ failure mutate myocarditis Pneumonia Pro protease proteolytic activation RdRP reducing mortality Remdesivir Replication respiratory respiratory distress RNA-dependent RNA polymerase SARS-CoV-2 SARS-CoV-2 replication severe acute respiratory syndrome Coronavirus Severe case severe cases Spike protein Spread subset supplementary material supportive care Symptom syndrome the SARS-CoV-2 the spike protein therapeutic target therapy Transcription Viral viral replication
[DOI] 10.1186/s12985-021-01526-y PMC 바로가기 [Article Type] Review