Synthetic flavonoids as potential antiviral agents against SARS-CoV-2 main protease
SARS-CoV-2 주요 프로테아제에 대한 잠재적인 항바이러스제로서의 합성 플라보노이드
Article
Published on
Journal: Journal of biomolecular structure & dynamics [Category] COVID19(2023년), SARS, 신약개발, 치료제,
Journal: Journal of biomolecular structure & dynamics [Category] COVID19(2023년), SARS, 신약개발, 치료제,
[키워드] 3-benzyloxyflavones
3-O-flavonol glycosides
antiviral agent
antiviral drug
antiviral drugs
binding
binding affinity
binding free energy
catalytic dyad
causative agent
claimed
complex
Compound
computational studies
Computational study
conserved
COVID-19
COVID-19 pandemic
crystal structure
demonstrated
docking
Drug discovery
effective
facilitated
filtered
flavonoids
flavonols
free energy
Free energy calculations
healthcare providers
in silico
In silico methods
in-silico
Infection
inhibit
inhibitor
Interaction
iterative
M pro
molecular
molecular docking
molecules
oxoaurones
Panic
performed
protease
protein-ligand
reproduction
residue
resulting
SARS-CoV-2
SARS-CoV-2 main protease
stability
substrate binding site
synthetic
targeting
thioaurones
thioflavonols.
Treatment
treatment of COVID-19
unavailability
Vaccine
Virtual screening
[DOI] 10.1080/07391102.2020.1850359 PMC 바로가기 [Article Type] Article
[DOI] 10.1080/07391102.2020.1850359 PMC 바로가기 [Article Type] Article