Challenge Trials: What Are the Ethical Problems?도전 시도: 윤리적 문제는 무엇입니까?Article Published on 2021-01-252022-09-11 Journal: The Journal of medicine and philosophy [Category] Coronavirus, 임상, [키워드] benefit challenge challenge trials claimed comparable COVID-19 expected human subjects individual kidney limit pandemic researcher risk SARS-CoV-2 Trial trials Vaccine vaccine trials Volunteer volunteers [DOI] 10.1093/jmp/jhaa028 PMC 바로가기 [Article Type] Article
Reduction of Physical Activity Levels During the COVID-19 Pandemic Might Negatively Disturb Sleep PatternPsychology Published on 2020-12-102022-10-31 Journal: Frontiers in Psychology [Category] COVID-19, [키워드] 95% CI activity added affecting Analysis association Binary logistic regression BMI Care caused changes in confounder COVID-19 Depression Disruption Effect exercise Google form Health influence information Insufficient lack Level mental health Model Mortality novel coronavirus disease objective outbreak Panic parameter pattern physical activity physical activity level quarantine reduction reported Result risk factor Sleep sleep quality statistical volunteers was used [DOI] 10.3389/fpsyg.2020.586157 PMC 바로가기 [Article Type] Psychology
The effect of constitutive pigmentation on the measured emissivity of human skinResearch Article Published on 2020-11-252022-10-28 Journal: PLoS ONE [Category] Coronavirus, MERS, SARS, [키워드] Affect ANOVA applied Body body temperature calculated Clinical practice COVID-19 pandemic diagnostic difference electrical group Human Infrared camera initial investigated not affect participant Pigmentation provided quantified Radiation Research Result Safe significant difference skin pigmentation tape temperature Variation volunteers were assessed [DOI] 10.1371/journal.pone.0241843 PMC 바로가기 [Article Type] Research Article
From research to rapid response: mass COVID-19 testing by volunteers at the Centre for Genomic Regulation연구부터 신속한 대응까지: 유전체규제센터 자원봉사자들의 대규모 코로나19 검사Opinion Article Published on 2020-11-162022-09-11 Journal: F1000Research [Category] MERS, SARS, 유전자 메커니즘, [키워드] Barcelona collaboration Community contribute COVID-19 pandemic COVID-19 testing Critical cure develop Government Health help Infection Research risk Spain the epidemic Vaccine Volunteer volunteers [DOI] 10.12688/f1000research.27497.1 PMC 바로가기 [Article Type] Opinion Article
Seroprevalence of anti‐SARS‐CoV‐2 antibodies in COVID‐19 patients and healthy volunteers up to 6 months post disease onset질병 발병 후 최대 6개월까지 COVID-19 환자 및 건강한 지원자에서 항-SARS-CoV-2 항체의 혈청유병률Clinical Trial Published on 2020-11-102022-08-13 Journal: European Journal of Immunology [Category] MERS, SARS, 임상, 진단, 치료기술, [키워드] age Anti‐SARS‐CoV‐2 antibody response Anti‐SARS‐CoV‐2 antibody responses anti‐SARS‐CoV‐2 IgG antibody antibody antibody production Antibody Response Antibody titer Asymptomatic circulating classic Clinical signs COVID‐19 COVID‐19 patient COVID‐19 described detect detectable disease onset Fever healthcare Healthcare workers healthy volunteer highlight hospital human pathogen humoral immune response IgA antibodies IgA antibody IgG IgG antibodies IgM immune response immunological information initial longitudinal analysis men Mild MONITOR neutralising antibody neutralization activity Neutralizing antibodies Patient peaking proportion protective immunity Protein provide quantified rapid increase RBD receptor‐binding domain recognizing reduce remained robust SARS‐CoV‐2 SARS‐CoV‐2 screened Seroprevalence setup Severity of disease Spread subject subjects Symptoms tested the Spike titre titres university virus volunteers were infected [DOI] 10.1002/eji.202048970 PMC 바로가기 [Article Type] Clinical Trial
Sample adequacy controls for infectious disease diagnosis by oral swabbing구강 면봉으로 감염병 진단을 위한 샘플 적합성 관리Research Article Published on 2020-10-302022-09-10 Journal: PLoS ONE [Category] MERS, SARS, 진단, 치료기술, 치료제, [키워드] applied can not cell type collected Control COVID-19 Cq values Cutoff detect diagnosing Diagnosis DNA Ebola evaluated exhibited expected healthy human cell human cells Infectious disease Infectious diseases mitochondrial mitochondrial DNA mouth negative control negative controls Non-invasive not used oral oral cavity oral microbiota oral swab oral swabs Paired analysis PCR qPCR quantification quantitative PCR representing SACs Sample Sensitivity and specificity South Africa Streptococcus species Streptococcus specy subjects Swab swabbing swabs target cell TB patient TB patients tongue Tuberculosis volunteers [DOI] 10.1371/journal.pone.0241542 PMC 바로가기 [Article Type] Research Article
Seroprevalence of Antibodies against SARS-CoV-2 among the Personnel and Students of the National and Kapodistrian University of Athens, Greece: A Preliminary ReportCommunication Published on 2020-09-212022-10-29 Journal: International Review of Cell and Molecular Biology [Category] COVID-19, [키워드] anti-SARS-CoV-2 antibody Asymptomatic category collected continuous monitoring COVID-19 Donor female FIVE Greece hospitalized patients implementation Infection involved knowledge male National and Kapodistrian University of Athens no statistical difference pandemic participant plasma sample positive Prevalence progression provide public health public health measures Randomly remained report response SARS-CoV-2 SARS-CoV-2 antibodies SARS-COV-2 infection School Science selected Seroepidemiological study Seroprevalence Serosurvey student tested university volunteers [DOI] 10.3390/life10090214 PMC 바로가기 [Article Type] Communication
A Systematic, Unbiased Mapping of CD8 + and CD4 + T Cell Epitopes in Yellow Fever VaccineesImmunology Published on 2020-08-312022-11-01 Journal: Frontiers in Immunology [Category] Coronavirus, MERS, SARS, [키워드] Analysis approach binding blood sample CD4 CD4+ and CD8+ T cell epitope discovery CD8 Cohort Combination confounding effect convalescent Coverage demonstrated diagnostic epitope Evidence Ex vivo Examining false discovery rate flanking regions forward-reverse immunology HLA HLA class I HLA haplotype humans identify immunodominance and immunodomination immunodominant immunogenicity include information isotypes magnitude mapping overlapping pathogen patients peptide peptide epitopes peptide-MHC predictors peptide-MHC tetramers predictor prevalent protein antigen proteome reduce representing required response responses Restricted risk SARS-CoV-2 specificity staining Support Survivors T cell T cell epitope T cell epitopes T cell response T cell responses therapeutic vaccination virus volunteers yellow yellow fever vaccination [DOI] 10.3389/fimmu.2020.01836 PMC 바로가기 [Article Type] Immunology
Viewpoint of a WHO Advisory Group Tasked to Consider Establishing a Closely-Monitored Challenge Model of COVID-19 in Healthy VolunteersViewpoints Published on 2020-08-282022-10-31 Journal: Clinical Infectious Diseases: An Official Publicat [Category] COVID-19, MERS, SARS, [키워드] adult volunteers Adults challenge Challenge model COVID-19 doses Efficacy Establishing experimental challenge feasibility group healthy lack limitation Model predict Prevent progression SARS-CoV-2 SARS-COV-2 infection Transmissibility Transmission vaccination Vaccine virus volunteers WHO [DOI] 10.1093/cid/ciaa1290 PMC 바로가기 [Article Type] Viewpoints
A COVID‐19 human viral challenge model. Learning from experienceInvited Review Article Published on 2020-08-122022-10-30 Journal: Influenza and Other Respiratory Viruses [Category] COVID-19, MERS, SARS, [키워드] accelerate clinical trial contagious Controlled human infection model COVID‐19 COVID‐19 determine develop effective Efficacy evaluate experience help human infection human viral challenge model infect Infection learning pathogenic potential benefit potential therapy respiratory syncytial virus RSV SARS‐CoV‐2 virus SARS‐CoV‐19 the vaccine Treatment Vaccine viral challenge virus volunteers [DOI] 10.1111/irv.12797 PMC 바로가기 [Article Type] Invited Review Article