Age, sex, and comorbidities predict ICU admission or mortality in cases with SARS-CoV2 infection: a population-based cohort studyResearch Letter Published on 2020-07-282022-11-01 Journal: Critical Care [Category] COVID-19, [키워드] Comorbidity ICU admission Mortality population-based cohort predict SARS-CoV2 Sex [DOI] 10.1186/s13054-020-03173-1 PMC 바로가기 [Article Type] Research Letter
Gossip, Rumors, and the COVID-19 CrisisLetter to the Editor Published on 2020-07-272023-06-13 Journal: Disaster Medicine and Public Health Preparedness [Category] MERS, [키워드] COVID-19 gossip rumor SARS-CoV2 social media [DOI] 10.1017/dmp.2020.272 PMC 바로가기 [Article Type] Letter to the Editor
Phosphodiesterase Inhibitors: Could They Be Beneficial for the Treatment of COVID-19?Review Published on 2020-07-272022-10-29 Journal: International Journal of Molecular Sciences [Category] COVID-19, SARS, [키워드] acute respiratory syndrome adopted CAMP cellular cGMP China clinical manifestations Clinical sign Combination condition conserved coronavirus COVID-19 Cytokine storm disorder distribution drug drugs effective fibrosis function Health highlighting hydrolyzing enzymes Hypothesis identify Infection Inflammation inhibitor inhibitors knowledge limit measure modulating nucleotide organ outcomes overlapping pan-selective inhibitors pandemic pandemic disease pathology PDE phosphodiesterase Pneumonia post infection reduce SARS-CoV-2 SARS-CoV2 SARS-CoV2 infection severe complication similarity Spread Support Symptom targets the epidemic thrombosis treated Treatment urgency virus World Health Organization [DOI] 10.3390/ijms21155338 PMC 바로가기 [Article Type] Review
Novel coronavirus and trauma surgery: successful infection control from a level I trauma centreOriginal Article Published on 2020-07-252022-11-01 Journal: European Journal of Trauma and Emergency Surgery [Category] COVID-19, MERS, SARS, [키워드] absence adjusted Care Contamination coronavirus COVID-19 effective element Health healthcare personnel help Hungary infected patient Infection infection control involved novel pandemic Patient care Patient care protocol protocol public health crisis recommendation reducing Result SARS-CoV2 Spread supplementary material surgeon trauma Treatment [DOI] 10.1007/s00068-020-01435-9 PMC 바로가기 [Article Type] Original Article
Patients with immune-mediated inflammatory diseases receiving cytokine inhibitors have low prevalence of SARS-CoV-2 seroconversionArticle Published on 2020-07-242022-10-04 Journal: Nature Communications [Category] 진단, [키워드] anti-SARS-CoV-2 antibody coronavirus disease COVID-19 COVID19 Crohn's disease cytokine cytokine inhibitor Epidemiology Gut healthy control Immune-mediated inflammatory disease incidence Inflammatory cytokines inflammatory disease inhibitor involved jak inhibitors joints observé Pathogenesis pathology Patient patients treated populations Prevalence PROTECT Protective receiving reduced response rheumatoid arthritis Safe SARS-CoV-2 SARS-COV-2 infection SARS-CoV2 Seroconversion severe COVID-19 treated Treatment viral infection [DOI] 10.1038/s41467-020-17703-6 PMC 바로가기 [Article Type] Article
Flavonoids Activation of the Transcription Factor Nrf2 as a Hypothesis Approach for the Prevention and Modulation of SARS-CoV-2 Infection SeverityHypothesis Published on 2020-07-242022-10-28 Journal: The Cochrane database of systematic reviews [Category] COVID-19, [키워드] ACE2 ACE2 receptors activate Activation acute respiratory syndrome age angiotensin-converting enzyme 2 antioxidant Antiviral Cell conditions coronavirus COVID-19 decrease disease pathogenesis downregulating EGCG ENhance expression Factor flavonoid flavonoids Genes high affinity Hypothesis immune response increase infections Inflammation inflammatory process Innate immunity modulate modulated Nrf2 obesity oxidative stress pathway Prevent prevention priming PROTECT Proteins receptor reduce reducing respiratory epithelial cells respiratory viral infections ROS SARS-CoV-2 SARS-COV-2 infection SARS-CoV2 severity spike glycoprotein thymoquinone transcription factor viral entry viral infection viral life cycle Vitamin D3 [DOI] 10.3390/antiox9080659 PMC 바로가기 [Article Type] Hypothesis
HLA-B*44 and C*01 Prevalence Correlates with Covid19 Spreading across ItalyCommunication Published on 2020-07-232022-10-29 Journal: International Journal of Molecular Sciences [Category] COVID-19, [키워드] allele alleles Analysis analyzed Anti-viral Antigen approach case-control studies Clinical management coefficient confounding factors coronavirus correlation COVID-19 Department ecological examined fixed growth HLA HLA allele HLA allele prevalence HLA class I immune response incidence incidence rate increase in infections involved Italian Italy leukocyte limit multiple regression model National outbreak P -value positive Prevalence protection provided registry retrieved risk SARS-COV-2 infection SARS-CoV2 service spread of COVID-19 spreading to define underlie vaccination viral infection susceptibility with COVID-19 [DOI] 10.3390/ijms21155205 PMC 바로가기 [Article Type] Communication
What we may learn – and need – from pandemic fictionEditorial Published on 2020-07-212022-10-29 Journal: Philosophy, Ethics, and Humanities in Medicine : P [Category] Coronavirus, SARS, [키워드] Cognition COVID-19 pandemic SARS-CoV2 Science fiction [DOI] 10.1186/s13010-020-00089-0 PMC 바로가기 [Article Type] Editorial
COVID-19: A Review on Diagnosis, Treatment, and ProphylaxisReview Published on 2020-07-212022-10-29 Journal: International Journal of Molecular Sciences [Category] COVID-19, SARS, [키워드] ACE2 addition Affect angiotensin Anti-inflammatory drugs antibody attenuate binding CD4+ T cell CD8+ clinical trial common cold contribute coronavirus 2 correlated country CoV COVID-19 infection develop diffusion drug Efficacy enzymatic activity Frequency functional healthcare identify immune immune system immunization in viral infect Infection involved measure Neutralizing antibodies outbreak outcome pandemic Patient Perspective Pneumonia positive prevention receptor Replication resources respiratory review SARS-CoV2 SARS-CoV2 infection severe respiratory syndrome severity single-stranded RNA virus Symptom the disease Tocilizumab Transcription Treatment turn Vaccine virus [DOI] 10.3390/ijms21145145 PMC 바로가기 [Article Type] Review
SARS-CoV-2 Entry Receptor ACE2 Is Expressed on Very Small CD45 − Precursors of Hematopoietic and Endothelial Cells and in Response to Virus Spike Protein Activates the Nlrp3 InflammasomeArticle Published on 2020-07-202022-10-28 Journal: Stem cell reviews and reports [Category] COVID-19, MERS, [키워드] ACE2 ACE2 receptor activate Ang II CD133 CD34 CD45 Cell cell death cell lysis cells COVID19 Cytokine storm damaged described Effect endothelial entry receptor enzyme Express expressed functional Genes hematopoietic Hematopoietic stem cell hematopoietic stem cells human cells hyperactivate indicate induce infect Inflammasome Interaction murine NLRP3 inflammasome progenitor cell protease TMPRSS2 protective effect pyroptosis RAAS raise receptor response SARS-CoV-2 SARS-CoV2 shown spike Spike protein stem cell stem cells the SARS-CoV-2 these cell tissue transmembrane umbilical cord blood viral spike protein virus VSELs [DOI] 10.1007/s12015-020-10010-z PMC 바로가기 [Article Type] Article