Immunization with SARS Coronavirus Vaccines Leads to Pulmonary Immunopathology on Challenge with the SARS VirusResearch Article Published on 2012-04-202022-10-28 Journal: PLoS ONE [Category] Coronavirus, [키워드] acute respiratory syndrome antibody C57BL/6 candidate vaccine caution challenge change changes in China component control group country dosage eosinophil evaluated exhibited ferret Histopathology Human hypersensitivity immunopathology inactivated indicated Infection infiltration Influenza initiated led to Live virus lung Lung disease mice NHP occurred Occurrence pathologic PBS pulmonary responses Result S protein SARS Coronavirus SARS-CoV SARS-CoV vaccine serum antibody Serum neutralizing antibody severe Significant reduction significantly spread to Th2-type the vaccine Vaccine Vaccine development virus VLP [DOI] 10.1371/journal.pone.0035421 PMC 바로가기 [Article Type] Research Article
Ready, Set, Fuse! The Coronavirus Spike Protein and Acquisition of Fusion CompetenceReview Published on 2012-04-122022-10-28 Journal: Viruses [Category] Coronavirus, [키워드] activate angiotensin converting enzyme 2 antiviral therapies Carcinoembryonic antigen cathepsin cofactor competence coronavirus Coronavirus infection endocytosis Endosomes fusion highlight Interaction interactions membrane fusion other protease protease Proteins receptor response S protein S proteins spike Spike protein transmembrane protease transmembrane serine protease triggers TTSPs viral pathogenesis viral spike virus virus entry virus-cell membrane fusion [DOI] 10.3390/v4040557 PMC 바로가기 [Article Type] Review
Pathogenesis and Tissue Distribution of Avian Infectious Bronchitis Virus Isolate IRFIBV32 (793/B Serotype) in Experimentally Infected Broiler ChickensResearch Article Published on 2012-04-012022-10-29 Journal: The Scientific World Journal [Category] Coronavirus, [키워드] age Antibody titer Broiler bronchitis chicken Clinical sign collected control group demonstrated Depression detected digestive distribution exhibited experimental group indicated Infected Infectious Bronchitis Virus inoculated intranasally isolate kidney lung mild respiratory number of infected oviduct Randomly RNA serotype tissue Trachea two group various tissue viral disease Viral RNA virus virus detection was reduced [DOI] 10.1100/2012/402537 PMC 바로가기 [Article Type] Research Article
The Coronavirus E Protein: Assembly and BeyondReview Published on 2012-03-082022-10-28 Journal: Viruses [Category] Coronavirus, [키워드] assembly coronavirus coronavirus assembly E protein envelope protein function Golgi complex highlight Host host proteins indicated Infection interact ion channel membrane membrane protein membrane protein topology recent related Stress topologies virions virus [DOI] 10.3390/v4030363 PMC 바로가기 [Article Type] Review
Reverse Genetics of SARS-Related Coronavirus Using Vaccinia Virus-Based RecombinationResearch Article Published on 2012-03-072022-10-28 Journal: PLoS ONE [Category] Coronavirus, [키워드] absence acute respiratory syndrome Analysis antiviral drug approach caused cDNA Cell characterization classical cloned Comparative analysis culture supernatant dendritic cell effective expressing facilitate Gene Expression generate Genome HCoV-229E Health Heterologous human coronavirus 229E in vitro transcription infectious Infectious virus led to less original form outbreak parental pathogenic plaque produced public health measures released Renilla luciferase Renilla luciferase gene Replication replication kinetics reporter reverse genetic system risk RNA transcript RNA transcripts robust SARS-CoV SARS-CoV Frankfurt-1 SARS-related coronavirus severe transfection Vaccines vaccinia vaccinia virus vectors virulent virus zoonotic disease [DOI] 10.1371/journal.pone.0032857 PMC 바로가기 [Article Type] Research Article
Etiology and Clinical Characterization of Respiratory Virus Infections in Adult Patients Attending an Emergency Department in BeijingResearch Article Published on 2012-02-282022-10-28 Journal: PLoS ONE [Category] Coronavirus, [키워드] addressed Adult assay Attending Beijing characterization checked China clinical clinical symptom conducted Department detected determine different dominant effective Emergency epidemiological finding HCoV-229E Health highlight human coronavirus Influenza virus métapneumovirus nose parainfluenza pathogen Patient picornavirus polymerase chain positive Prevalence profile real-time RT-PCR reported respiratory respiratory syncytial virus respiratory tract infection respiratory virus Respiratory virus infection respiratory viruses reverse transcription RSV Safe significantly tested Therapeutic approach throat swab virus virus infection viruses [DOI] 10.1371/journal.pone.0032174 PMC 바로가기 [Article Type] Research Article
Emerging Viruses in the Felidae: Shifting ParadigmsReview Published on 2012-02-072022-10-28 Journal: Viruses [Category] Coronavirus, [키워드] cancers concerning disease Diseases emerging virus FCoV Felidae Feline infectious peritonitis FeLV FIV Genetic HIV/AIDS human disease immune impairment infectious agent Interpretation paradigm Pathogenesis pathogenic Transmission virulence virulent virus [DOI] 10.3390/v4020236 PMC 바로가기 [Article Type] Review
Pandemic (H1N1) 2009 in Captive CheetahDispatch Published on 2012-02-012023-05-31 Journal: Emerging Infectious Diseases [Category] Fulltext, 신종인플루엔자, 조류인플루엔자, [키워드] Acinonyx jubatus cheetahs China H1N1 subtype Influenza influenza A virus Pandemic (H1N1) 2009 Pandemics virus zoonoses [DOI] 10.3201/eid1802.111245 PMC 바로가기 [Article Type] Dispatch
Oseltamivir-Resistant Pandemic (H1N1) 2009 Virus Infections, United States, 2010–11Article Published on 2012-02-012023-06-08 Journal: Emerging Infectious Diseases [Category] Fulltext, 신종인플루엔자, [키워드] antiviral drug resistance H1N1 virus Influenza influenza A oseltamivir Oseltamivir resistance pandemic Pandemic (H1N1) 2009 United States virus [DOI] 10.3201/eid1802.111466 PMC 바로가기
The Murine Coronavirus Hemagglutinin-esterase Receptor-binding Site: A Major Shift in Ligand Specificity through Modest Changes in ArchitectureResearch Article Published on 2012-01-262022-10-29 Journal: PLoS Pathogens [Category] Coronavirus, [키워드] absence architecture Author Bacteria Betacoronavirus binding binding site cell tropism change changed changes in complex consequence coronavirus Coronaviruses domain domains Evolution example Factor glycan glycoprotein Hemagglutinin-esterase Interaction Ligand Lineage living cell Major MHV modifications MOST mouse hepatitis virus murine organ Pathogenesis Protein Protozoa receptor resolved shift sialic acid specificity sugar Topology vertebrates virion virus [DOI] 10.1371/journal.ppat.1002492 PMC 바로가기 [Article Type] Research Article