Self-Assembling Nanoparticle Vaccines Displaying the Receptor Binding Domain of SARS-CoV-2 Elicit Robust Protective Immune Responses in Rhesus MonkeysSARS-CoV-2의 수용체 결합 도메인을 표시하는 자가 조립 나노입자 백신은 붉은털 원숭이에서 강력한 보호 면역 반응을 이끌어냅니다Article Published on 2021-05-192022-09-11 Journal: Bioconjugate chemistry [Category] SARS, 비임상, 진단, [키워드] Analysis Antigen benefit breath candidate vaccine caused Cell Clinical trial design COVID-19 pandemic cross-neutralize domain effective effective vaccine Efficiency elicit eukaryotic expression ferritin Focusing Humoral immunity immune response immunization immunization program immunized Infection inhibited isolates Monkey nanoparticle nasal Neutralizing antibodies neutralizing antibody new SARS-CoV-2 observation pathology platform protection test purified RBD respiratory response Rhesus monkey Rhesus monkeys Safe SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 spike protein SARS-CoV-2 strain SARS-CoV-2 virus significantly specific antigen Spike protein T cell the vaccine Vaccine vaccine candidate vaccine platform virus replication [DOI] 10.1021/acs.bioconjchem.1c00208 PMC 바로가기 [Article Type] Article
COVID-19 vaccines: progress and understanding on quality control and evaluationPerspective Published on 2021-05-182022-10-04 Journal: Signal Transduction and Targeted Therapy [Category] Fulltext, SARS, 변종, 임상, [키워드] accelerate accelerated approval authority biologics Candidates center China countermeasure COVID-19 COVID-19 vaccine COVID-19 vaccines drug Drug regulation effective Emergency use FIVE Guidance Health involved Laboratory National organization outbreak progression Quality control Research supported the vaccine Travel Vaccine vaccine candidates vaccine platform Vaccines with COVID-19 [DOI] 10.1038/s41392-021-00621-4 PMC 바로가기 [Article Type] Perspective
Knowledge, Attitudes and Perceptions of COVID-19 Vaccination among Healthcare Workers of an Inner-City Hospital in New YorkArticle Published on 2021-05-172022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] affected age approach approval Attitude Community conducted contracting the virus correlated COVID-19 COVID-19 pandemic COVID-19 vaccination demographics effective Factor Gender healthcare worker Healthcare workers high risk hospital IMPROVE information knowledge Multivariate analysis New York New York City Perception Personal protective equipment Predictive reduction in risk Risk perception significantly The United States the vaccine Vaccine Vaccine attitudes Vaccine hesitancy virus worker [DOI] 10.3390/vaccines9050516 PMC 바로가기 [Article Type] Article
Factors Affecting COVID-19 Vaccine Acceptance: An International Survey among Low- and Middle-Income CountriesArticle Published on 2021-05-172022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] Africa African age Bangladesh Brazil chronic disease conducted country Coverage COVID-19 COVID-19 pandemic COVID-19 vaccine cross-sectional develop effective Effectiveness Factor female gender FIVE healthcare worker highest identify individual Intervention knowledge lack LMICs Malaysia nine Prevalence PROTECT Psychological distress reduced refusal Research Side effect survey Thailand the vaccine Uganda vaccination Vaccine Vaccine acceptance Vaccine hesitancy with COVID-19 [DOI] 10.3390/vaccines9050515 PMC 바로가기 [Article Type] Article
Willingness to Be Vaccinated against COVID-19 in Spain before the Start of Vaccination: A Cross-Sectional StudyArticle Published on 2021-05-152022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, SARS, [키워드] Cancer Consensus COVID-19 COVID-19 vaccine disinformation Effectiveness evaluate Factor Factors greater Health hypertension identify Immunity immunization program information lack Logistic regression male multivariate logistic regression offer Older Participants Patient Probability questionnaire reduce Respiratory disease resulting SARS-CoV-2 Sociodemographic Spain Spanish the vaccine vaccination Vaccination campaign Vaccine Vaccine acceptance Vaccine hesitancy Vaccines was performed [DOI] 10.3390/ijerph18105272 PMC 바로가기 [Article Type] Article
Impact and effectiveness of mRNA BNT162b2 vaccine against SARS-CoV-2 infections and COVID-19 cases, hospitalisations, and deaths following a nationwide vaccination campaign in Israel: an observational study using national surveillance data이스라엘의 전국적인 예방접종 캠페인에 따른 SARS-CoV-2 감염 및 COVID-19 사례, 입원 및 사망에 대한 mRNA BNT162b2 백신의 영향 및 효과: 국가 감시 데이터를 사용한 관찰 연구Observational Study Published on 2021-05-152022-09-11 Journal: Lancet (London, England) [Category] Fulltext, SARS, 변종, 임상, [키워드] 95% CI adjusted age all age group all age groups Analysis Asymptomatic asymptomatic infection authorisation B.1.1.7 B.1.1.7 SARS-CoV-2 variant B.1.1.7 variant BNT162b2 calculated caused Coverage COVID-19 COVID-19 cases COVID-19 vaccination COVID-19 vaccine COVID-19-related death Critical death Decline declined defined dose effective Effectiveness Emergency use estimate evaluate help hospitalisation hospitalisations Impact incidence incidence rate incidence rates individual International laboratory-confirmed SARS-CoV-2 infection Ministry of Health MoH mRNA mRNA BNT162b2 vaccine National non-proprietary name of BNT162b2 Older outcome outcomes pandemic PCR test Pfizer-BioNTech Prevalence prevelance proportion receiving Regression model SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections SARS-CoV-2-positive specimen second dose second dose of vaccine severe disease Sex spike gene surveillance data sustained symptomatic symptomatic and asymptomatic symptomatic COVID-19 symptomatic infection tested the vaccine vaccinated individual vaccinated individuals vaccination Vaccine was used widespread [DOI] 10.1016/S0140-6736(21)00947-8 PMC 바로가기 [Article Type] Observational Study
Strategies for Vaccine Prioritization and Mass DispensingArticle Published on 2021-05-142022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] Analysis attack rate biological-behavior-logistics-queueing computational framework combating COVID-19 pandemic determine disease Dispensing Effect effective Efficacy effort healthcare help highlight human behavior Infectious disease Intervention mass mass vaccination medical resource mixed vaccination strategy mortality rate mortality rates Mutation Outbreaks pandemic parameter platform protective effect real time reduce resource robust significantly Strategy Support switch trigger switching the vaccine vaccination Vaccination strategy Vaccine vaccine efficacy vaccine prioritization Vaccines Variation virus [DOI] 10.3390/vaccines9050506 PMC 바로가기 [Article Type] Article
Public attitudes toward COVID-19 vaccination: The role of vaccine attributes, incentives, and misinformationArticle Published on 2021-05-142022-10-04 Journal: NPJ Vaccines [Category] 임상, [키워드] acute respiratory syndrome American attributes authorization Community coronavirus COVID-19 COVID-19 treatment COVID-19 vaccine Efficacy effort Emergency Evidence examined had no Health care implication incidence Intervention Lucid pandemic platform preferences Public public health receive recruited Side effects significantly increased the vaccine Translational research vaccinate vaccination Vaccine Vaccine hesitancy while [DOI] 10.1038/s41541-021-00335-2 PMC 바로가기 [Article Type] Article
Effectiveness of the Pfizer-BioNTech and Oxford-AstraZeneca vaccines on covid-19 related symptoms, hospital admissions, and mortality in older adults in England: test negative case-control study화이자-바이오엔텍 및 옥스포드-아스트라제네카 백신이 영국 노인의 코로나19 관련 증상, 입원 및 사망률에 미치는 효과: 음성 사례 대조 연구 테스트Observational Study Published on 2021-05-132022-09-11 Journal: The BMJ [Category] Fulltext, SARS, 변종, 임상, [키워드] 95% confidence interval Admission Admissions Adults B.1.1.7 B.1.1.7 variant baseline BNT162b2 case-control study ChAdOx1 ChAdOx1-S Chain Reaction Combined commenced COVID-19 symptoms death deaths dose duration of follow-up Effect effective Effectiveness Effects England higher odd higher odds hospital Hospital admission Hospital admissions immunisation individuals Mortality nine Odds ratio of BNT162b2 Older outcome Oxford-AstraZeneca participant Pfizer-BioNTech polymerase chain polymerase chain reaction positive Primary outcomes protection reached reduced risk reduction in reported symptom risk risk of infection SARS-CoV-2 infections second dose severe disease single dose Symptom symptomatic symptomatic COVID-19 symptomatic disease Symptoms System Test test negative the vaccine vaccination Vaccine variant [DOI] 10.1136/bmj.n1088 PMC 바로가기 [Article Type] Observational Study
The safety and immunogenicity of an inactivated SARS-CoV-2 vaccine in Chinese adults aged 18-59 years: A phase I randomized, double-blinded, controlled trial18-59세 중국 성인을 대상으로 한 비활성화된 SARS-CoV-2 백신의 안전성 및 면역원성: 1상 무작위, 이중 맹검, 대조 시험Clinical Trial Published on 2021-05-122022-09-12 Journal: Vaccine [Category] MERS, SARS, 비임상, 임상, 진단, [키워드] Administered Adverse reaction antibody Chinese Controlled trial CTL cytokine cytotoxic T lymphocyte dose double-blinded evaluated examined fatigue genetic diversity geometric mean titer GMTs healthy Immune cell immune response immunogenic immunopathology inactivated Inactivated vaccine injection intervals intramuscularly Mild N protein occurred Pain phase Phase I Placebo placebo-controlled trial Randomized Safe SARS-CoV-2 SARS-CoV-2 vaccine seroconversion rate subjects synchronous the S protein the vaccine transcriptome analysis Trial upregulation virion [DOI] 10.1016/j.vaccine.2021.04.006 PMC 바로가기 [Article Type] Clinical Trial