Comparison of viral load between saliva and nasopharyngeal swabs for SARS-CoV2: the role of days of symptoms onset on diagnosisOriginal Article Published on 2021-04-162022-10-29 Journal: Memórias do Instituto Oswaldo Cruz [Category] COVID-19, MERS, SARS, [키워드] acute respiratory syndrome Ageusia Anosmia collected coronavirus Coronavirus disease 2019 cough COVID-19 COVID-19 diagnosis death decrease Diagnosis evaluate fatigue Fever FIVE Headaches healthcare mild symptoms myalgia Nasopharyngeal swab nasopharyngeal swabs nine no significant difference presenting reduce reported rhinorrhea risk of infection RT-PCR Saliva saliva specimen SARS-CoV-2 sensitivity significant changes in sore throat specimen subject Swab symptoms onset Viral load was performed [DOI] 10.1590/0074-02760210018 PMC 바로가기 [Article Type] Original Article
When lockdown policies amplify social inequalities in COVID-19 infections: evidence from a cross-sectional population-based survey in FranceResearch Article Published on 2021-04-122022-10-28 Journal: BMC Public Health [Category] COVID-19, MERS, [키워드] activity affected Ageusia amplify Anosmia chronic disease Cohort Comorbidities conditions conducted cough country COVID-19 COVID-19 incidence COVID-19 infection COVID-19 infections COVID-19 related mortality COVID-19 symptoms Critical cross-sectional cross-sectional survey defined Dyspnea effective Evidence Factor Fever First wave France French Gender General population Health highest identify individual less lockdown lockdown policy Measures multinomial regression National Occurrence outcome participant populations Prevalence PROTECT recorded reduce reducing Region remained reported Result Risk factors shown Significant Social inequalities supplementary material [DOI] 10.1186/s12889-021-10521-5 PMC 바로가기 [Article Type] Research Article
Efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine against SARS-CoV-2 variant of concern 202012/01 (B.1.1.7): an exploratory analysis of a randomised controlled trial우려되는 SARS-CoV-2 변이체에 대한 ChAdOx1 nCoV-19(AZD1222) 백신의 효능 202012/01(B.1.1.7): 무작위 대조 시험의 탐색적 분석Clinical Trial Published on 2021-04-102022-08-13 Journal: Lancet (London, England) [Category] MERS, SARS, 변종, 임상, 진단, [키워드] 1:1 95% CI adenoviral vector vaccine Ageusia analysed Anosmia assigned AstraZeneca AZD1222 B.1.1.7 B.1.1.7 lineage B.1.1.7 variant booster dose booster doses calculated canonical ChAdOx1 ChAdOx1 nCoV-19 Clinical research Clinical vaccine efficacy Coalition collected cough COVID-19 COVID-19 disease disease dominant Efficacy efficacy analysis efficacy cohort enrolled Exploratory analysis female Fever finding funding Genomics geometric mean geometric mean ratio groups in vitro Infection Innovation ISRCTN Lineage lineages MenACWY microneutralisation assay NAAT NAAT positive NAAT positive swab network neutralisation activity neutralising antibody response Neutralising antibody responses NIHR NIHR Oxford Biomedical Research Centre non-B.1.1.7 variant nose and throat nucleic acid nucleic acid amplification nucleic acid amplification test Oxford participant phase 2/3 Poisson regression model positive sample post-hoc analysis provided randomised controlled trial Randomly receive recruited reduced Registered Relative risk risk robust SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 variant second dose second dose of vaccine sequenced seronegative participant seronegative participants Shortness of breath South Swab swabs symptomatic symptomatic COVID-19 symptoms of COVID-19 tested the vaccine throat swabs Trial upper airway upper airway swab Vaccine vaccine efficacy vaccine-induced antibodies vaccine-induced antibody Valley variant variant of SARS-CoV-2 Victoria Victoria lineage virus neutralisation activity were measured [DOI] 10.1016/S0140-6736(21)00628-0 PMC 바로가기 [Article Type] Clinical Trial
Virtualized clinical studies to assess the natural history and impact of gut microbiome modulation in non-hospitalized patients with mild to moderate COVID-19 a randomized, open-label, prospective study with a parallel group study evaluating the physiologic effects of KB109 on gut microbiota structure and function: a structured summary of a study protocol for a randomized controlled study입원하지 않은 경증에서 중등도의 COVID-19 환자에서 장내 미생물군유전체 조절의 자연사 및 영향을 평가하기 위한 가상화된 임상 연구 장내 미생물군 구조에 대한 KB109의 생리학적 효과를 평가하는 병렬 그룹 연구와 함께 무작위, 공개, 전향적 연구 및 기능: 무작위 대조 연구를 위한 연구 프로토콜의 구조화된 요약Letter Published on 2021-04-022022-09-10 Journal: Trials [Category] MERS, SARS, 임상, [키워드] 1:1 24 hours Ability absence addition adhere Affect age Ageusia allergy analysed Anosmia Anosmia/ageusia Antacid Antibiotics Antiviral assessment assigned Autoimmune disease Bariatric surgery baseline bilevel positive airway pressure Biomarker Biomarkers biomarkers of inflammation BiPAP Blinding blocker Blood blood sample Blood samples both groups bowel bowel resection breath Care care provider Cell change Chest chest tightness chills chronic lung disease cirrhosis clinical clinical study clinical trial Cold collected Community Comorbidity comparator Patients completion Compliance component computer Concomitant medication concomitant medications concurrent condition conducted contraindications coronavirus disease Coronavirus disease 2019 cough COVID-19 COVID-19 in patient COVID-19 symptom COVID-19 symptoms COVID-19 testing COVID-19-related symptom COVID-19-related symptoms COVID-19–related symptom COVID-19–related symptoms CPAP Cytokines D-dimer daily dose Day defined diarrhea dissemination drug duration of symptom Effect element eligible Enrollment evaluate evaluate the effect evaluated exacerbated exclusion criteria exploratory fatigue fatty Fatty acid feasible Female patients Fever fiber Follow-up follow-up period following group Gut gut microbiome gut microbiome composition gut microbiota headache Health Health care Health Care Utilization Health status healthcare Histamine history hospital Hospital admission Hospital admissions Hospitalization Hospitalized hypoxia Identifier IgM/IgG Immunity immunomodulatory immunosuppressive immunosuppressive therapy in both group include Infection Inflammation Inflammatory biomarker Inflammatory bowel disease information Informed consent inhibitors intake Interaction investigational agent irritable bowel syndrome KB109 Laboratory laboratory measures lactating library life Liver disease Lung disease magnitude malignancy management measure Measures medication medications Medicine metabolite Microbiome microbiota Mild mild to moderate Mild to moderate COVID-19 mild to moderate disease moderate Moderate COVID-19 moderate disease modulate modulation muscle pain nasal congestion neutralization assays not limited nucleic acid number objective Open-label opinion other compound other compounds outcome outcome measure Outpatient outpatients oxygen oxygen saturation Oxygen therapy Pain parallel group participant Participation Patient patient population Period Physical examination positive airway pressure Positive test Potential pre-symptomatic pregnant Primary outcome progression proportion proportions Prospective Study PROTECT protocol protocols proton pump provided pulse Pulse oximeter Quality of life Quantitative question randomisation randomised randomised controlled study randomization Randomized randomized controlled study receive recruitment reduction Registered reported response resting position risk risk of infection Sample size screened selected self-care sensitivities Sequencing serological serology shaking short-chain fatty acids Shortness of breath Sleep sleep apnea Smartphone sore throat specific biomarker specific biomarkers Spread SSC Standard Stool stratified Study design Study protocol study visit supplementary material Swab Symptom symptomatic patient Symptomatic patients Symptoms syndrome Tablet TEAEs Telemedicine telephone temperature the patient The United States therapy time Tolerability Treatment treatment-emergent adverse event undergo United States unlikely Viral Viral load water website worsening [DOI] 10.1186/s13063-021-05157-0 PMC 바로가기 [Article Type] Letter
Coronavirus disease 2019 and first-trimester spontaneous abortion: a case-control study of 225 pregnant patients2019년 코로나바이러스 질병 및 임신 초기 자연유산: 225명의 임산부를 대상으로 한 사례 대조 연구Article Published on 2021-04-012022-09-11 Journal: American journal of obstetrics and gynecology [Category] MERS, SARS, 진단, 치료기술, [키워드] 2019 abortion acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Ageusia Anosmia antibody appear arthralgia blood sample case-control study caused collected conducted confidence interval Control control group coronavirus coronavirus disease Coronavirus disease 2019 cough Course COVID-19 cumulative cumulative incidence current demographics determined by diarrhea disease early pregnancy evaluated Evidence fetus Fever first trimester global public health global public health emergency groups Hospital admission Immunoglobulin Immunoglobulin G immunoglobulin M incidence independent Infection Logistic regression analysis miscarriage Nasopharyngeal swab no difference not differ Odds ratio Pneumonia positive test result Pregnancy pregnancy loss pregnant patient pregnant women Preterm birth regression analysis respiratory risk factor SARS-CoV-2 Seroprevalence Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus spontaneous abortion Symptom Symptoms test result Transmission Turin vertical transmission Viral viral infection viral infections was determined were recorded women [DOI] 10.1016/j.ajog.2020.10.005 PMC 바로가기 [Article Type] Article
The importance of anosmia, ageusia and age in community presentation of symptomatic and asymptomatic SARS-CoV-2 infection in Louisiana, USA; a cross-sectional prevalence study미국 루이지애나 주에서 증상 및 무증상 SARS-CoV-2 감염의 지역 사회 표현에서 후각, 노인성 및 연령의 중요성; 횡단면 유병률 연구Article Published on 2021-04-012022-09-12 Journal: Clinical microbiology and infection : the official [Category] MERS, SARS, 진단, [키워드] 95% CI acute respiratory syndrome age Ageusia Analysis Anosmia Anosmia/ageusia antibody Asymptomatic Asymptomatic individuals asymptomatic infection blood draw can be used change Cluster co-morbidities Community Contact tracing coronavirus cross-sectional Frequency help highest IgG illnesses incidence include Infection linear mitigate Nasopharyngeal swab New Orlean PCR performed positive Positive test prevalence study Probability quantification quantity Regular reporting symptom Rouge SARS-CoV-2 SARS-COV-2 infection Severe acute respiratory syndrome coronavirus 2 prevalence Spread Symptom Symptom incidence. symptom status symptomatic symptomatic and asymptomatic tested USA virus were given were used while without symptoms [DOI] 10.1016/j.cmi.2020.12.029 PMC 바로가기 [Article Type] Article
Self-reported smell and taste alteration as the sole clinical manifestation of SARS-CoV-2 infectionSARS-CoV-2 감염의 유일한 임상 징후로서 자가 보고된 냄새 및 미각 변화Case Reports Published on 2021-04-012022-09-11 Journal: Oral surgery, oral medicine, oral pathology and or [Category] SARS, 치료기술, [키워드] absence acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Ageusia alteration Analysis Anosmia chemosensory clinical manifestation coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19-related symptom dentist develop Diagnostic Criteria dysfunction Early detection Evidence facilitate Gustatory had no healthy Hypogeusia Hyposmia Inclusion increasingly Infection knowledge olfactory Patient positive test result Radiographic reported respiratory symptom SARS-CoV-2 SARS-COV-2 infection severe acute respiratory syndrome Coronavirus sinusitis Support symptoms of COVID-19 Taste test result the disease [DOI] 10.1016/j.oooo.2020.11.016 PMC 바로가기 [Article Type] Case Reports
Predicting Severity and Intrahospital Mortality in COVID-19: The Place and Role of Oxidative StressCOVID-19의 중증도 및 병원 내 사망률 예측: 산화 스트레스의 위치와 역할Observational Study Published on 2021-03-262022-09-10 Journal: Oxidative Medicine and Cellular Longevity [Category] MERS, SARS, 바이오마커, 임상, [키워드] acute respiratory syndrome Admission Ageusia Anosmia approved biochemical blood cell cause Clinical Center Clinical Center Kragujevac Clinical signs clinical study Committee Comorbidity conducted COVID-19 COVID-19 infection COVID-19 mortality COVID-19 severity cross-sectional determine diagnosed Dyspnea ethical committee global pandemic group heart rate hematological Hospital admission hypertension ICU Infection inflammatory markers Laboratory laboratory procedures LDH Linear regression model Mild moderate Mortality nitric oxide on admission outcome Patient predictor respiratory Result role SARS-CoV-2 SARS-CoV-2 disease SARS-CoV-2 virus Serum level serum levels Severe acute respiratory syndrome severe COVID-19 severe disease severity significantly higher significantly lower Superoxide Symptoms Viral viral infection White blood cell white blood cell count [DOI] 10.1155/2021/6615787 PMC 바로가기 [Article Type] Observational Study
Symptoms and symptom clusters associated with SARS-CoV-2 infection in community-based populations: Results from a statewide epidemiological study지역 사회 기반 인구에서 SARS-CoV-2 감염과 관련된 증상 및 증상 클러스터: 주 전체 역학 연구 결과Research Article Published on 2021-03-242022-09-12 Journal: PLoS ONE [Category] SARS, 진단, [키워드] Ageusia Anosmia Asymptomatic calculated Care chest pain clinical trials Cluster Combination combinations Community Community-based cohort cough disease spread EFA Epidemiological study Exploratory factor analysis Fever flu help Hispanic Hospitalized identify IMPROVE individual individual symptom individual symptoms individuals infected individuals Infection Mitigation multivariable logistic regression Negative predictive value NPV Older Other respiratory viruses outcome Population positive Positive predictive value PPV Predictive value prevalence study primary symptom public health respiratory viruses Result robust RT-PCR SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 positivity screened sensitivity Shortness of breath specificity Support Symptom Symptom Cluster symptom clusters Symptoms symptoms of COVID-19 therapeutic these symptoms understanding urban area Vaccine with infection [DOI] 10.1371/journal.pone.0241875 PMC 바로가기 [Article Type] Research Article
Concomitant Guillain-Barre syndrome with COVID-19: a case reportCase Report Published on 2021-03-232022-10-27 Journal: BMC Neurology [Category] COVID-19, [키워드] Admission Ageusia Analysis Anosmia association bacterial pathogen Barranquilla Case report case-control study cerebrospinal fluid clinical evolution Clinical improvement Concomitant Coronavirus disease 2019 COVID-19 determine Diagnosis diagnostic diaphragmatic discharged facial Factor Guillain-barrè syndrome headache hospital hospitalisation Hospitalization hypertensive Immune-mediated induce intensive care investigated lower limb Medical Research Council muscular nerve tissue neurological manifestation pandemic Patient positive result reported SARS-CoV-2 SARS-COV-2 infection subtype supportive care Symptom syndrome the patient upper limb was performed weakness with COVID-19 [DOI] 10.1186/s12883-021-02162-3 PMC 바로가기 [Article Type] Case Report