Bronchoalveolar lavage – Page 12 – Communicable Diseases Research

Fatal outcome of anti-MDA5 juvenile dermatomyositis in a paediatric COVID-19 patient: a case report

소아 코로나19 환자에서 발생한 항MDA5 소아 피부근염의 치명적 결과: 증례 보고

Case Reports

Published on 2021-01-012022-09-11
Journal: Modern rheumatology case reports [Category] 진단, 치료제,

Compartmental immunophenotyping in COVID-19 ARDS: A case series

Clinical Trial

Published on 2021-01-012022-10-05
Journal: The Journal of Allergy and Clinical Immunology [Category] SARS, 임상,

[키워드] Activation acute respiratory distress acute respiratory distress syndrome ARDS Blood bronchoalveolar Bronchoalveolar lavage Bronchoalveolar lavage fluid case sery CD4 CD8 T cell CD8 T-cell Cell coronavirus disease COVID-19 Critically ill patient cytokine Cytokines Deleterious distress evaluated exhibit expressed flow cytometry fraction hyperinflammation Hyperinflammatory IL-1ra IL-6 IL-8 immunopathology intubation IP-10 less leukocyte lung Lungs lymphopenia Macrophage manifestation marker mechanically ventilated patient moderate-to-severe COVID-19 monocyte multiplex neutrophil Patient phenotype Regulatory T cell Stage subpopulation syndrome upregulation were assessed were expressed with COVID-19
[DOI] 10.1016/j.jaci.2020.09.009 PMC 바로가기 [Article Type] Clinical Trial

Responses to acute infection with SARS-CoV-2 in the lungs of rhesus macaques, baboons and marmosets

붉은털원숭이, 개코원숭이 및 마모셋 폐의 SARS-CoV-2 급성 감염에 대한 반응

Article

Published on 2021-01-012022-09-12
Journal: Nature Microbiology [Category] MERS, SARS, 진단,

[키워드] acute infection acute respiratory syndrome adaptive age antibody Baboon Bronchoalveolar lavage bystander Cellular immune response Clinical sign clinical trials Computed tomography coronavirus coronavirus disease COVID-19 cytokine production cytokine response distress group humans Immune cell immunohistochemical analyses Infection interferon response lung Lung inflammation Lungs macaque macaques memory Mild moderate Non-human Pathologies progression response rhesus macaques SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2-specific IgG T-cell Therapies titre Vaccine viral infection Viral RNA shedding was increased
[DOI] 10.1038/s41564-020-00841-4 PMC 바로가기 [Article Type] Article

Detection of SARS-CoV-2 pneumonia: two case reports

SARS-CoV-2 폐렴 진단: 2건의 사례 보고

Case Reports

Published on 2020-12-112022-09-10
Journal: Journal of Medical Case Reports [Category] MERS, SARS, 진단, 치료기술,

Usefulness of bronchoalveolar lavage in suspect COVID-19 repeatedly negative swab test and interstitial lung disease

반복적으로 음성 면봉 검사 및 간질성 폐 질환이 의심되는 COVID-19에서 기관지 폐포 세척의 유용성

Article

Published on 2020-12-012022-09-12
Journal: Journal of global antimicrobial resistance [Category] MERS, SARS, 진단,

[키워드] Abstract Bronchoalveolar lavage bronchoscopy coronavirus COVID-19 Interstitial lung disease interstitial pneumonia SARS-CoV-2 Swab test
[DOI] 10.1016/j.jgar.2020.07.030 PMC 바로가기 [Article Type] Article

A randomized, multicentre, open-label phase II proof-of-concept trial investigating the clinical efficacy and safety of the addition of convalescent plasma to the standard of care in patients hospitalized with COVID-19: the Donated Antibodies Working against nCoV (DAWn-Plasma) trial

COVID-19로 입원한 환자의 표준 치료에 회복기 혈장 추가의 임상 효능과 안전성을 조사하는 무작위, 다기관, 공개 라벨 2상 개념 증명 시험: nCoV에 대항하는 기증된 항체(DAWn- 플라즈마) 시험

Clinical Trial

Published on 2020-11-272022-08-13
Journal: Trials [Category] SARS, 임상, 진단,

[키워드] absence active treatment addition administration Belgium Bronchoalveolar lavage Clinical efficacy clinical status convalescent plasma COVID-19 infection COVID-19 pandemic defined diagnosed with COVID-19 Diagnosis diagnosis of COVID-19 died Effect eligible feature Health care Health care system health care systems Hospitalized hospitalized patient hospitalized patients Immunity include Infection Influenza information Intervention mechanical ventilation Mortality multicentre nCoV novel SARS-CoV-2 virus Open-label Ordinal Scale past Patient patients hospitalized PCR primary endpoint proof-of-concept clinical trial proportion radiological randomization Randomized receive recruit Registered Safe SARS-CoV-2 virus secondary endpoint Standard of care study inclusion supplementary material Support Swab symptomatic the disease the WHO Treatment treatment group Trial Trial registration with COVID-19 working
[DOI] 10.1186/s13063-020-04876-0 PMC 바로가기 [Article Type] Clinical Trial

An integrative analysis identifying transcriptional features and key genes involved in COVID-19

COVID-19와 관련된 전사적 특징과 핵심 유전자를 식별하는 통합 분석

Research Article

Published on 2020-11-262022-09-11
Journal: Epigenomics [Category] SARS, 유전자 메커니즘, 진단,

Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques

SARS-CoV-2에 감염된 붉은털 원숭이의 혈관 질환 및 혈전증

Case Reports

Published on 2020-11-252022-09-11
Journal: Cell [Category] MERS, SARS, 유전자 메커니즘, 진단,

[키워드] Analysis Bronchoalveolar lavage C-reactive protein clinical Clinical features Coagulation collagen complement COVID-19 COVID-19 pandemic Critical endothelial feature Human IFNα IL-1 IL-6 IL-8 include infected with SARS-CoV-2 Inflammation Inflammatory Interaction lead lung Lungs macaque macaques Macrophage molecular morbidity and mortality MX1 NF-κB pathway performed Peripheral blood Platelet platelet activation potential therapeutic target potential therapeutic targets proinflammatory proteomic rhesus macaque rhesus macaques SARS-CoV-2 SARS-CoV-2 pathogenesis serum thrombosis TNFα transcriptomic Transcriptomic analyses upregulation Vascular vascular disease vascular thrombosis vWF
[DOI] 10.1016/j.cell.2020.10.005 PMC 바로가기 [Article Type] Case Reports

Broncho-alveolar inflammation in COVID-19 patients: a correlation with clinical outcome

Research Article

Published on 2020-11-162022-10-28
Journal: BMC Pulmonary Medicine [Category] COVID-19, Fulltext, SARS,

[키워드] Activation acute respiratory syndrome alveolar alveolitis Anti-viral antibodies Antiviral BAL Bronchoalveolar lavage Care Cell cell count Clinical outcome Concentration conducted coronavirus correlation COVID-19 Cytokines effector feature fraction groups Hyperactivation ICU ICU patient IL10 IL6 IL8 immunostaining increase in Infection Inflammation inflammatory cascade inflammatory status interleukin intermediate lung lymphocyte Macrophage Medicine Microscopy mononuclear cell Nasopharyngeal swab neutrophil pandemic Patient patients treated patients with moderate patients with SARS-CoV-2 pro-inflammatory cytokine proportions Prospective Study reached Real-time PCR Result SARS-CoV-2 severe COVID-19 severe pneumonia significantly higher steroid supplementary material Survivors sustained Tocilizumab Transmission treated Treatment ultrastructure Variation viral particle ward was performed with COVID-19
[DOI] 10.1186/s12890-020-01343-z PMC 바로가기 [Article Type] Research Article

Comparison of SARS-CoV-2 RT-PCR on a high-throughput molecular diagnostic platform and the cobas SARS-CoV-2 test for the diagnostic of COVID-19 on various clinical samples

Comparative Study

Published on 2020-11-112023-07-12
Journal: Pathogens and disease [Category] SARS,

[키워드] anal swab anorectal swab bronchial aspirate Bronchoalveolar lavage Cobas 6800 COVID-19 Nasopharyngeal swab RT-PCR, molecular diagnostic SARS-CoV-2
[DOI] 10.1093/femspd/ftaa061 PMC 바로가기 [Article Type] Comparative Study