Comparison of the clinical signs, pathological and immuohistochemical findings in visceral organs of chickens experimentally infected with Salmonella Zega through three routesarticle Published on 2019-12-312024-09-01 Journal: Family process [Category] 살모넬라증, [키워드] chickens Clinical signs Immunohistochemical findings pathology Salmonella Zega [Article Type] article
Effect of Pullet Vaccination on Development and Longevity of ImmunityArticle Published on 2019-02-022022-10-28 Journal: Viruses [Category] Coronavirus, [키워드] Administered administration age Antibody Response Antibody titer cause ciliostasis Clinical signs determine development disease Effect evaluated group Histopathology homologous IBV Immunity Infectious Bronchitis Virus Infectious laryngotracheitis virus information interfere Live attenuated vaccine Longevity newcastle disease virus occur pathogen PROTECT protective immunity Respiratory disease respiratory pathogen respiratory tract serum tracheal vaccination Vaccination program Vaccine Vaccines variety Viral load virus [DOI] 10.3390/v11020135 PMC 바로가기 [Article Type] Article
The Characterization of Immunoprotection Induced by a cDNA Clone Derived from the Attenuated Taiwan Porcine Epidemic Diarrhea Virus Pintung 52 StrainArticle Published on 2018-10-042022-10-28 Journal: Viruses [Category] Coronavirus, [키워드] antigenicity attenuation cDNA characterization Clinical signs clone comparable detectable determinant effective Effective vaccines elicited epidemic diarrhea facilitate fecal full-length cDNA Host immune response IgA immunogenic immunoprotection in vitro in vivo induced infectious clone inoculated less Modification neutralizing antibody titers parental PEDV plasma IgG replication kinetics reverse genetics strain Taiwan Vaccine vaccine platform Vero cells viral genome Viral load viral pathogenesis viral shedding virulent virus [DOI] 10.3390/v10100543 PMC 바로가기 [Article Type] Article
First retrospective studies with etiological confirmation of porcine transmissible gastroenteritis virus infection in ArgentinaResearch Article Published on 2018-09-242022-10-28 Journal: BMC veterinary research [Category] Coronavirus, MERS, [키워드] animal Antibiotics Antigen case sery characterized circulating Clinical diagnosis Clinical signs Complete coronavirus criteria detect determine Diagnosis diarrhea distribution Endemic epidemiological etiological evaluated Final gastroenteritis granular histological immunohistochemistry increase in Infection intestine lesion Microscopy monoclonal morbidity Mortality mRNA neonatal diarrhea Neonatal Mortality organization Particle pathogen PEDV Piglets Porcine transmissible gastroenteritis virus Region respond Result Retrospective study serological service Spike protein supplementary material TGEV viral infection virus virus infection was performed watery [DOI] 10.1186/s12917-018-1615-9 PMC 바로가기 [Article Type] Research Article
Recombinant Infectious Bronchitis Viruses Expressing Chimeric Spike Glycoproteins Induce Partial Protective Immunity against Homologous Challenge despite Limited Replication In VivoVaccines and Antiviral Agents Published on 2018-09-122022-10-30 Journal: Journal of Virology [Category] Coronavirus, MERS, [키워드] avian infectious bronchitis virus BeauR bronchitis cause cellular challenge Characteristics characterized chimeric ciliary Clinical sign Clinical signs conducted conformational contagious coronavirus cross-protection determine expressing glycoprotein Heterologous homologous IBV IMPROVE in vitro in vivo induce Limited Live attenuated vaccines M41 mucosal tissue Partial partial protection PROTECT protective immunity recombinant recombinant vaccine reduction in reductions in replicated Replication Respiratory disease responsible rIBV S1 S1 and S2 S2 subunit serotype serum serum antibody single vaccination spike strain surface protein the S1 subunit tracheal Trial vaccination Vaccine Viral load viral RNA load virulent virus [DOI] 10.1128/JVI.01473-18 PMC 바로가기 [Article Type] Vaccines and Antiviral Agents
Display of Porcine Epidemic Diarrhea Virus Spike Protein on Baculovirus to Improve Immunogenicity and Protective EfficacyArticle Published on 2018-06-272022-10-28 Journal: Viruses [Category] Coronavirus, [키워드] Asia baculovirus baculovirus display system Clinical signs clinical symptom complex control group control groups demonstrated disease display displaying effective elicited epidemic diarrhea exhibited experiment fecal full-length S protein generate Genotype IgG immune response immunization immunized immunogen immunogenicity Infection Intramuscular injection killing less mice Mild mimicking Modification Neonatal neutralizing antibody North America PEDV Protein robust Safe significantly significantly higher spike spike vaccine Taiwan the S1 protein vaccine candidate variant viral shedding virulent virus [DOI] 10.3390/v10070346 PMC 바로가기 [Article Type] Article
Clinical signs in cornea and ocular surfaceReview Article for Residents Published on 2018-02-012024-09-04 Journal: Indian journal of ophthalmology [Category] 대상포진, [키워드] Clinical signs Cornea corneal diagram Follicles papillae tear film [DOI] 10.4103/ijo.IJO_716_17 PMC 바로가기 [Article Type] Review Article for Residents
Enhanced inflammation in New Zealand white rabbits when MERS-CoV reinfection occurs in the absence of neutralizing antibodyResearch Article Published on 2017-08-172022-10-29 Journal: PLoS Pathogens [Category] Coronavirus, [키워드] absence accompanied acute respiratory disease antibody Asymptomatic case asymptomatic infection Betacoronavirus Clinical signs complement confirmed case Contact tracing deaths develop dose-dependent elicited enhanced Human implication increase in individual Infection Inflammation Inflammatory response inoculated intranasal Lung disease Lung inflammation lung lobe MERS-CoV Middle East Mild naïve Neutralizing activity neutralizing antibody Neutralizing antibody response Neutralizing antibody titer New non-neutralizing antibody occur perivascular inflammation Primary infection PROTECT Protein Proteins Pulmonary infection pulmonary inflammation recruitment Reinfection reported respiratory syndrome coronavirus risk serum subsequent transfer Viral antigen viral challenge Viral protein Viral RNA waned while zoonotic [DOI] 10.1371/journal.ppat.1006565 PMC 바로가기 [Article Type] Research Article
Isolation and characterization of porcine epidemic diarrhea virus associated with the 2014 disease outbreak in Mexico: case reportResearch Article Published on 2016-06-292022-10-28 Journal: BMC veterinary research [Category] Coronavirus, [키워드] acute infection amplification Analysis Case report caused characterization characterized clinical sample Clinical sign Clinical signs Culture Cytopathic effect disease epidemic diarrhea histological homology identify initial interest isolate Isolation lesion Mexico Microscopy molecular Mortality mortality rate necropsy nucleotide sequence observation outbreak PEDV Porcine epidemic diarrhea virus Protein Result RT-PCR S glycoprotein Sequencing staining state TCID the United State trypsin USA Vero Cell Virological virus virus particle was determined was performed [DOI] 10.1186/s12917-016-0763-z PMC 바로가기 [Article Type] Research Article
Bovine coronavirus in naturally and experimentally exposed calves; viral shedding and the potential for transmissionResearch Published on 2016-06-132022-10-28 Journal: Virology Journal [Category] Coronavirus, [키워드] analyzed antibodies BCoV BCV biosecurity Blood Clinical signs concerning conducted Contact coronavirus correlated cough Depression detectable disease euthanized experiment Experimental infection fecal group Hypothesis Infection information investigated knowledge lack lymphatic tissue Mild naïve nasal nasal swabs occur pathogen potential for transmission prevention producing Prolonged provide rectal respiratory rate Respiratory system Result RNA RT-qPCR secretion seropositive supplementary material swabs temperature tissue tissue sample transmission potential Viral RNA viral shedding Viremia virus virus isolation Virus quantification Virus shedding virus spread was performed [DOI] 10.1186/s12985-016-0555-x PMC 바로가기 [Article Type] Research