Pharmacokinetics and pharmacodynamics of hydroxychloroquine in hospitalized patients with COVID-19
COVID-19 입원 환자에서 하이드록시클로로퀸의 약동학 및 약력학
Observational Study
[키워드] 95% confidence interval
Administered
Analysis
Bioavailability
C-reactive protein
circulating
clearance
Concentration
covariates
COVID-19
COVID-19 patient
COVID-19 patients
daily dose
distribution
dosage
dose
e parameters
effective
elimination half-life
estimate
followed by
half-life
HCQ
hospitalized patient
hospitalized patients
Hydroxychloroquine
in vitro
Inflammation
inhibit
intensive care units
Liquid chromatography
Loading doses
Lupus
median
nasopharyngeal swabs
Non-COVID-19 patients
parameter
Patient
performed
Pharmacodynamics
pharmacokinetic
pharmacokinetic analysis
pharmacokinetic data
pharmacokinetics
plasma
plasma concentration
ranged
reported
required
reverse transcription-PCR
SARS-CoV-2
SARS-CoV-2 viral
severe COVID-19 patient
severe COVID-19 patients
tested
Variability
viral clearance
Volume
volume of distribution
were measured
with COVID-19
[DOI] 10.1016/j.therap.2021.01.056 PMC 바로가기 [Article Type] Observational Study
[DOI] 10.1016/j.therap.2021.01.056 PMC 바로가기 [Article Type] Observational Study